Team:Nanjing-China/Model
Overview
Modeling plays an increasingly vital role in the research of synthetic biology. Then, what is modeling? Modeling aims to build and use a model which provides a theoretical explanation for a phenomenon in simpler fashion than real situation. The procedure of modeling consists of observing a phenomenon, identifying influential parameters and filtering decisive ones. According to the results of modeling, you may predict what would happen under different conditions.
In the modeling part, we have now completed two models:
In the first model, we have constructed a hydrogen production system through the diffusion equation of gas. In this system, we obtained the steady state solution of hydrogen-oxygen, and obtained the hydrogen-oxygen concentration, which is consistent with the experimental data.
In the second model, we used the Logistics equation and the Gompertz equation to fit the data of the growth phase of E. coli, and compared the correlation parameters, which proved the stability of the encapsulation.
Through modeling, we know hydrogen bio-production system better and are given an essential guidance to our project. Besides, we can also find out whether our wet lab results conform to the modeling results.
Here comes our modeling.
Model 1: Simulation of hydrogen production system
Model 2: Growth Curve Fitting
Reference
[1] Matsunaga N, Sakai G, Shimanoe K, et al. Formulation of gas diffusion dynamics for thin film semiconductor gas sensor based on simple reaction–diffusion equation[J]. Sensors and Actuators B: Chemical, 2003, 96(1): 226-233.
[2] Tsoularis A, Wallace J. Analysis of logistic growth models[J]. Mathematical Biosciences, 2002, 179(1):21-55.
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CONTACT
Address
- Life Science Department
- #163 Xianlin Blvd, Qixia District
- Nanjing University
- Nanjing, Jiangsu Province
- P.R. of China
- Zip: 210046
- nanjing_china@163.com
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南京大学
生命科学学院
SCHOOL OF LIFE SCIENCES
NANJING UNIVERSITY
南京大学
NANJING UNIVERSITY
南京大学
化学化工学院
SCHOOL OF CHEMISTRY AND CHEMICAL ENGINEERING
NANJING UNIVERSITY
