Difference between revisions of "Team:SDU-Denmark/Parts"

Line 20: Line 20:
 
<h3><strong>Composite</strong></h3>
 
<h3><strong>Composite</strong></h3>
 
<p><a href="http://parts.igem.org/Part:BBa_K2018010" target="blank"><strong>BBa_K2018010</strong></a></p>
 
<p><a href="http://parts.igem.org/Part:BBa_K2018010" target="blank"><strong>BBa_K2018010</strong></a></p>
<p><span style="font-weight: 400;">This BioBrick contain the coding region of </span><strong>Laterosporulin, </strong><span style="font-weight: 400;">a bacteriocin </span><span style="font-weight: 400;">produced by </span><em><span style="font-weight: 400;">Brevibacillus </span></em><span style="font-weight: 400;">sp. strain, and exhibit a broad spectrum of antibacterial activity against bacterias like: B. subtilis , S. aureus, E. coli, P. aeruginosa, &nbsp;and L. monocytogenes.</span></p>
+
<p><span style="font-weight: 400;">This part is a functional BioBrick contain the coding region of </span><strong>Laterosporulin, </strong><span style="font-weight: 400;">, with promoter, RBS and terminator. Laterosporulin is a bacteriocin produced by </span><em><span style="font-weight: 400;">Brevibacillus </span></em><span style="font-weight: 400;">sp. strain, and exhibit a broad spectrum of antibacterial activity against bacterias like:</span><em><span style="font-weight: 400;"> B. subtilis , S. aureus, E. coli, P. aeruginosa, &nbsp;and L. monocytogenes.</span></em><span style="font-weight: 400;"></span></p>
  
 
<p><a href="http://parts.igem.org/Part:BBa_K2018011" target="blank"><strong>BBa_K2018011</strong></a></p>
 
<p><a href="http://parts.igem.org/Part:BBa_K2018011" target="blank"><strong>BBa_K2018011</strong></a></p>

Revision as of 10:07, 12 October 2016

Parts


Basic

Composite

BBa_K2018010

This part is a functional BioBrick contain the coding region of Laterosporulin, , with promoter, RBS and terminator. Laterosporulin is a bacteriocin produced by Brevibacillus sp. strain, and exhibit a broad spectrum of antibacterial activity against bacterias like: B. subtilis , S. aureus, E. coli, P. aeruginosa,  and L. monocytogenes.

BBa_K2018011

This BioBrick contain the coding region of, Thuricin S, a bacteriocin produced by Bacillus thuringiensis. Thuricin S target a broad spectrum of pathogens, including Pseudonoas aeruginosa and Enterobactoer Cloacae which is often found in correlation to burn and wound infection.

BBa_K2018012

This BioBrick contain the coding region of Lacticin Q, a bacteriocin  produced by Lactococcus lactis QU5  and has shown bactericidal activity against Staphylococcus aureus [http://www.ncbi.nlm.nih.gov/pubmed/22538663]. It function by forming large toroidal pores by distributing membrane lipid organization.

BBa_K2018014

This BioBrick contain the coding region of Laterosporulin-Thuricin S, which is a hybrid bacteriocin with  Laterosporulin and Thuricin S we had designed.  

BBa_K2018015

This BioBrick contain the coding region of Lacticin Q-Lacticin Z, which is a hybrid bacteriocin with Lacticin Q and Lacticin Z we had designed.  

BBa_K2018019

This BioBrick contain the coding region of Pyocin S5, a bacteriocin produced by  a specific strain of P. aeruginosa and elicit its effect against other strains of P. aeruginosa. Pyocin causes the cell membrane of target cells to be permeable and thereby causing leakage of intracellular materials, which cause cell death [http://www.sciencedirect.com/science/article/pii/S0014579310005120].

BBa_K2018024

This BioBrick contains the coding region of our biofused phasin with a hemolysin A tag, so it is recognized for secretion by the type II hemolysin secretion pathway. This biobrick is designed to work with hemolysin B (K2018027) and hemolysin D (K2018029). This BioBrick will simply bid to PHA granules in the cytoplasm  and reduce the size of these.

Existing BioBrick parts