iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave
Back to the origins
Difference between revisions of "Team:Toulouse France"
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| − | + | <p style="text-align:center; font-size:18px;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i></p> | |
| − | + | <p style="text-align:center; font-size:18px;">Back to the origins<br><br><p> | |
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| − | + | <br>What if iGEM stepped 18,000 years back? | |
| − | + | <br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that cause colored spots on the frescoes.Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency. <br> | |
| − | + | <br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> bacterium that develops from bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about our environment, an inducible riboswitch-based double toxin/antitoxin system was created to preventDNA transmission and a physical device was designed to confine our strain. | |
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| − | + | <a href="https://2016.igem.org/Team:Toulouse_France/Description" class="part-little-projet"> | |
| − | + | <div class="title-part-projet">Project</div> | |
| − | + | <div style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px;">The project <b>Paleotilis</b> is composed of three modules: <b>Predation</b>, <b>Antifungals</b>, and <b>Confinement</b>. By following this link you will learn more about these constructions.</div> | |
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| − | + | <a class="part-large-projet" style="background: url('https://static.igem.org/mediawiki/2016/4/4b/Toulouse_France_LascauxFresqueTaureaux.png') no-repeat center;-webkit-background-size: cover;-moz-background-size: cover;-o-background-size: cover;background-size: cover;"> | |
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| − | + | <a href="https://2016.igem.org/Team:Toulouse_France/Demonstrate" class="part-little-projet"> | |
| − | + | <div class="title-part-projet">Results</div> | |
| − | + | <div style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">The different biobricks we have constructed have been tested to measure their efficiency. There you can have an overview of the results.</div> | |
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| − | + | <a href="https://2016.igem.org/Team:Toulouse_France/Human_Practices" class="part-little-projet"> | |
| − | + | <div class="title-part-projet">Human Practices</div> | |
| − | + | <div style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">Lot of projects and events have been done by the iGEM Toulouse team to complete our objective to <b>be nominated among the best Human Practice part</b>. Our work can be evaluated by following this link.</div> | |
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| + | To virtually visit the Lascaux cave ! | ||
| + | http://www.lascaux.culture.fr/#/fr/00.xml | ||
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| + | <center><a class="button-home" href="http://www.ladepeche.fr/article/2016/07/10/2382301-une-bacterie-toulousaine-au-chevet-des-fresques-de-lascaux.html" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 140px;">Read more</a></center> | ||
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| + | <center><img href="http://www.sudouest.fr/2016/08/09/comment-des-etudiantes-veulent-sauver-lascaux-avec-des-ogm-2461559-1980.php" class="thirteenth-slide" src="https://static.igem.org/mediawiki/2016/d/d3/Toulouse_France_SudOuest1.jpg" alt="sixth slide" style="max-height:450px; width:60%;"></center> | ||
| + | <center><a class="button-home" href="http://www.sudouest.fr/2016/08/09/comment-des-etudiantes-veulent-sauver-lascaux-avec-des-ogm-2461559-1980.php" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 140px;">Read more</a></center> | ||
</div> | </div> | ||
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| − | + | <center><a class="button-home" href="http://www.sudouest.fr/2016/09/20/lascaux-elles-veulent-sauver-ses-peintures-2506542-6204.php" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 140px;">Read more</a></center> | |
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| − | + | <!-- Left and right controls--> | |
| − | + | <a class="left carousel-control" href="#cover" role="button" data-slide="prev"> | |
| − | + | <p style="vertical-align: middle; margin: 80% 10%; font-size:30px; color:rgb(255,255,255);"><b><</b></p> | |
| − | + | <span class="sr-only">Previous</span> | |
| + | </a> | ||
| + | <a class="right carousel-control" href="#cover" role="button" data-slide="next"> | ||
| + | <p style="vertical-align:middle; margin: 80% 10%; float:right; font-size:30px; color:rgb(255,255,255);"><b>></b></p> | ||
| + | <span class="sr-only">Next</span> | ||
| + | </a> | ||
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| + | <style> | ||
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| + | <div class="column full_size" style="width:80%; margin:10px 10%;"> | ||
| + | |||
| + | <center> | ||
| + | <div class="title" id="achievements"> | ||
| + | <h3><strong>Achievements</strong></h3> | ||
| + | </div> | ||
| + | </center> | ||
| + | |||
| + | <table> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td style="width:50px"> | ||
| + | <center> | ||
| + | <img src="https://static.igem.org/mediawiki/2015/4/41/TLSE_Home_Medals_Bronze.PNG" style="width:100%;" /> | ||
| + | </center> | ||
| + | </td> | ||
| + | |||
| + | <td colspan="3"> | ||
| + | <ul><h3><strong>Bronze medal</strong></h3></ul> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
| + | |||
| + | <ul><ul><ul> | ||
| + | <ul align="justify" style="font-size:15px;"> | ||
| + | <li>Register to iGEM </li> | ||
| + | <li>Complete <a target="blank" href="https://igem.org/2016_Judging_Form?id=1937"> judging form</a></li> | ||
| + | <li>Wiki & Registry (from <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Composite_parts">?????????</a>)</li> | ||
| + | <li>Participate to Giant Jamboree </li> | ||
| + | <li><a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Attributions"> Attributions:</a> our project could be | ||
| + | possible thanks to several persons who helped us in different ways and we are very grateful</li> | ||
| + | <li>Add new BioBrick to the Registry: <a target="blank" href="http://parts.igem.org/#"> name of part</a> corresponds to <a target="blank" href=""> role</a> </li> | ||
| + | </ul> | ||
| + | </ul></ul></ul> | ||
| + | <br><br> | ||
| + | |||
| + | |||
| + | <table> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td style="width:50px"> | ||
| + | <center> | ||
| + | <img src="https://static.igem.org/mediawiki/2015/2/2c/TLSE_Home_Medals_Silver.PNG" style="width:100%;" /> | ||
| + | </center> | ||
| + | </td> | ||
| + | |||
| + | <td colspan="3"> | ||
| + | <ul><h3><strong>Silver medal</strong></h3></ul> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
| + | |||
| + | |||
| + | <ul><ul><ul> | ||
| + | <ul align="justify" style="font-size:15px;"> | ||
| + | <li>New BioBrick validated experimentally: <a target="blank" href="http://parts.igem.org/#"> ??</a> corresponds to <a target="blank" href="">???</a> </li> | ||
| + | <li>BioBrick <a target="blank" href="http://parts.igem.org/Part:#"> ???</a> submitted to the Registry</li> | ||
| + | <li>Strong commitment to <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Human_Practices">Practices:</a> Ethics, Safety, Education </li> | ||
| + | </ul> | ||
| + | </ul></ul></ul> | ||
| + | <br><br> | ||
| + | |||
| + | |||
| + | <table> | ||
| + | <tbody> | ||
| + | <tr> | ||
| + | <td style="width:50px"> | ||
| + | <center> | ||
| + | <img src="https://static.igem.org/mediawiki/2015/b/b0/TLSE_Home_Medals_Gold.PNG" style="width:100%;" /> | ||
| + | </center> | ||
| + | </td> | ||
| + | |||
| + | <td colspan="3"> | ||
| + | <ul><h3><strong>Gold medal</strong></h3></ul> | ||
| + | </td> | ||
| + | </tr> | ||
| + | </tbody> | ||
| + | </table> | ||
| + | |||
| + | |||
| + | <ul><ul><ul> | ||
| + | <ul align="justify" style="font-size:15px;"> | ||
| + | |||
| + | <li>Innovative human practices: </li> | ||
| + | <ul> | ||
| + | <strong>-</strong> Active participating in <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Engagement">ExpoScience international</a>??? <a target="blank" href="">exciting perspectives</a><br> | ||
| + | <strong>-</strong> Our project is based on a <b>deep</b><a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Human_Practices#Ethics"> Ethical reflection</a><br> | ||
| + | <strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Attributions#Media">Discussions with people</a> to fit the best with real issue<br> | ||
| + | <strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Engagement">Communication with kids</a><br> | ||
| + | </ul> | ||
| + | <li><a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Collaborations#collab">Collaborations:</a> </li> | ||
| + | <ul> | ||
| + | <strong>-</strong> Myhuyhuiujio <a target="blank" href=""> ednfhjzel <a target="blank" href=""> <br> | ||
| + | <strong>-</strong> <a target="blank" href="">Imperial College team:</a> dvjiofrekfoepln <br> | ||
| + | </ul> | ||
| + | |||
| + | </ul> | ||
| + | </ul></ul></ul> | ||
| + | <br><br> | ||
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Revision as of 20:02, 13 October 2016
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What if iGEM stepped 18,000 years back?
At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that cause colored spots on the frescoes.Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency.
At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered Bacillus subtilis bacterium that develops from bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about our environment, an inducible riboswitch-based double toxin/antitoxin system was created to preventDNA transmission and a physical device was designed to confine our strain.
Project
The project Paleotilis is composed of three modules: Predation, Antifungals, and Confinement. By following this link you will learn more about these constructions.
Read more
To virtually visit the Lascaux cave !
http://www.lascaux.culture.fr/#/fr/00.xml
Achievements
|
Bronze medal |
||
- Register to iGEM
- Complete judging form
- Wiki & Registry (from ?????????)
- Participate to Giant Jamboree
- Attributions: our project could be possible thanks to several persons who helped us in different ways and we are very grateful
- Add new BioBrick to the Registry: name of part corresponds to role
|
Silver medal |
||
- New BioBrick validated experimentally: ?? corresponds to ???
- BioBrick ??? submitted to the Registry
- Strong commitment to Practices: Ethics, Safety, Education
|
Gold medal |
||
- Innovative human practices:
- Collaborations:
-
- Active participating in ExpoScience international??? exciting perspectives
- Our project is based on a deep Ethical reflection
- Discussions with people to fit the best with real issue
- Communication with kids
-
- Myhuyhuiujio ednfhjzel
- Imperial College team: dvjiofrekfoepln
Website by Team iGEM Toulouse 2016
