Difference between revisions of "Team:Toulouse France"

<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that cause colored spots on the frescoes. Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency. <br>

<br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> bacterium that develops from bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about our environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.

<div style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px;">The project <b>Paleotilis</b> is composed of three modules: <b>Predation</b>, <b>Antifungals</b>, and <b>Confinement</b>. By following this link you will learn more about these constructions.</div>

<div  style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">The different biobricks we have constructed have been tested to measure their efficiency. There you can have an overview of the results.</div>

<div  style="position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">Lot of projects and events have been done by the iGEM Toulouse team. We aimed <b>to explain synthetic biology, to debate about the use of GMO and to transmit what we have learnt</b>.</div>

<li>Register the team to iGEM, have fun during the summer and attend the Giant Jamboree with smile</li>

<li>Submit successfully <a target="blank" href="https://igem.org/2016_Judging_Form?id=1937"> the Judging form</a></li>

<li>Create a page in the wiki with attributions to every people that helped us in different ways</li>

<li>Document a new BioBrick and add it to the registry parts: <a href="http://parts.igem.org/Part:BBa_K1937002">pSB1C3-OriKan (BBa_K1937002)</a> corresponds to a shuttle vector between <i>E.coli</i> and <i>B.subtilis</i>

<li>Create and share a complete description of the team’s project in the Wiki</li>

<li><a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Attributions"> Attributions:</a> our project could be

possible thanks to several persons who helped us in different ways and we are very grateful</li>

<li>Plan to present a beautiful poster and a pleasant Prezi presentation at the Giant Jamboree</li>