Difference between revisions of "Team:Toulouse France"

Latest revision as of 20:11, 19 October 2016

iGEM Toulouse 2016

iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave

Back to the origins

What if iGEM stepped 18,000 years back?

At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency.

At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered Bacillus subtilis strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.

Project

Discover the context of the Paleotilis project, and the three modules of its design: Predation, Antifungals, and Confinement. Click on the link to learn more about these constructions.

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 		<div style="background-color:rgba(1,1,1,0.9); float:bottom;">
 			<center>
-			<br><br><br>
+			<br>
 				<font color="white"><p style="text-align:center; font-size:18px; vertical-align:middle;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i>
 				<br><br> Back to the origins<br><br><p></font>
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 	<div class="column full_size">
 			<article align="justify;"  style="margin:10px 30px;">
-				<br>What if iGEM stepped 18,000 years back?
+				<br><b style="font-size:18px;">What if iGEM stepped 18,000 years back? </b>
-				<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency.	<br>
+				<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency.	<br>
 				<br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.
 			</article>
@@ Line 42: / Line 42: @@
 		<div class="line-gallerie-project">
 			<a href="https://2016.igem.org/Team:Toulouse_France/Context" class="part-little-projet">
-				 <div class="title-part-projet">Project</div>
+				 <div class="title-part-projet" style="text-align:center;">Project</div>
-				 <div style="text-align:justify; word-wrap: break-word;position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px;">Discover the context of the <b>Paleotilis</b> project, and the three modules of its design: <b>Predation</b>, <b>Antifungals</b>, and <b>Confinement</b>. Click on the link to learn more about these constructions.<br></div>
+				 <div style="text-align:justify; word-wrap: break-word;position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px;">Discover the context of the <b>Paleotilis</b> project, and the three modules of its design: <b>Predation</b>, <b>Antifungals</b>, and <b>Confinement</b>. Click on the link to learn more about these constructions.<br><br></div>
 				 <div style="border-bottom: 1px solid #fff; color:white; font-family:'Open Sans'; position:absolute; bottom:25px; right:22px; font-size:16px;">Read more</div>
 			</a>
@@ Line 60: / Line 60: @@
 			<a href="https://2016.igem.org/Team:Toulouse_France/Experiments" class="part-little-projet">
-				<div class="title-part-projet">Results</div>
+				<div class="title-part-projet" style="text-align:center;">Results</div>
-				<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">The different biobricks we constructed have been tested to measure their efficiency. There you will have an overview of the results.<br></div>
+				<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px">The different biobricks we constructed have been tested to measure their efficiency. There you will have an overview of the results.<br></div>
 				<div style="border-bottom: 1px solid #fff; color:white; font-family:'Open Sans'; position:absolute; bottom:28px; left:34px; font-size:16px;">Read more</div>
 			</a>
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 		<div class="line-gallerie-project">
 			<a href="https://2016.igem.org/Team:Toulouse_France/Human_Practices" class="part-little-projet">
-				<div class="title-part-projet">Human Practices</div>
+				<div class="title-part-projet" style="text-align:center;">Human Practices</div>
-				<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:200px; line-height:24px">Lot of projects and events have been done by the iGEM Toulouse team. We aimed <b>to explain synthetic biology, to debate about the use of GMOs and to transmit what we have learnt</b>.<br></div>
+				<div  style="text-align:justify;  word-wrap: break-word; position:absolute; top:90px; left:34px; color:white; font-family:'Open Sans'; font-size:16px; width:80%; line-height:24px">Lot of projects and events have been done by the iGEM Toulouse team. We aimed <b>to explain synthetic biology, to debate about the use of GMOs and to transmit what we have learnt</b>.<br><br></div>
 				<div style="border-bottom: 1px solid #fff; color:white; font-family:'Open Sans'; position:absolute; bottom:25px; right:34px; font-size:16px;">Read more </div>
 			</a>
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-	<div class="page" style="height:1500px; background-image:url('https://static.igem.org/mediawiki/2016/4/43/Toulouse_France_PanneauEmpreinte.jpg');">
-		<div class="column full_size" style="width:80%; margin:40px 10%; background-color:rgba(255,255,255,0.7);">
-			<center>
-				<div class="title" id="achievements">
-					<h3><strong>Achievements</strong></h3>
-				</div>
-			</center>
-			<table>
-				<tbody>
-					<tr>
-						<td style="width:50px">
-							<center>
-								<img src="https://static.igem.org/mediawiki/2016/8/88/Toulouse_France_MedBronze.png" style="width:100%;" />
-							</center>
-						</td>
-						<td colspan="3">
-							<ul><h3><strong>Bronze medal</strong></h3></ul>
-						</td>
-					</tr>
-				</tbody>
-			</table>
-			<ul><ul><ul>
-				<ul align="justify" style="font-size:15px;">
-					<li>We registered the team to iGEM, had fun during the all summer and attended the Giant Jamboree with smiles</li>
-					<li>We successfully submitted<a target="blank" href="https://igem.org/2016_Judging_Form?id=1937"> the Judging form</a></li>
-					<li>A page in the wiki with attributions to every people that helped us in any ways have been created</li>
-					<li>We documented 10 new BioBricks and added it to the registry: <a href="http://parts.igem.org/Part:BBa_K1937002">pSB1C3-OriKan (BBa_K1937002)</a> corresponds to a shuttle vector between <i>E.coli</i> and <i>B.subtilis</i>
-					<br>Registry (from <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Composite_parts"> See Parts</a>)</li>
-					<li>We created and shared a complete description of the team’s project in the Wiki</li>
-					<li>In the <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Attributions"> attributions:</a> section, we thank all the persons who made
-						this project possible by helping us in different ways and we are very grateful</li>
-					<li>And for sure, we will present to you a beautiful poster and our most pleasant Prezi presentation at the Giant Jamboree!</li>
-				</ul>
-			</ul></ul></ul>
-			<br><br>
-			<table>
-				<tbody>
-					<tr>
-						<td style="width:50px">
-							<center>
-								<img src="https://static.igem.org/mediawiki/2016/1/15/Toulouse_France_MedArgent.png" style="width:100%;" />
-							</center>
-						</td>
-						<td colspan="3">
-							<ul><h3><strong>Silver medal</strong></h3></ul>
-						</td>
-					</tr>
-				</tbody>
-			</table>
-			<ul><ul><ul>
-				<ul align="justify" style="font-size:15px;">
-					<li>Present strong commitment to Human Practices for <b>Science Popularization</b> by
-					participating to different events in France, for <b>Education</b> by developing an education
-					kit, for <b>Safety</b> by minimizing the risk of incidents in the lab and for <b>Ethics</b> by creating
-					a theatre play</li>
-					<li>Experimentally validate three new BioBricks: <a href="http://parts.igem.org/Part:BBa_K1937002">pSB1C3-OriKan (BBa_ K1937002)</a>, <a href="http://parts.igem.org/Part:BBa_K1937001">pSB(BS)0K-mini (BBa_ K1937001)</a> and <a href="http://parts.igem.org/Part:BBa_K1937003">PnagA (BBa_K1937003)</a> worked successfully as expected</li>
-					<li>Take part to active collaborations for the scientific community: creation of <b>Multilanguage protocol videos</b> thanks to 7 others teams</li>
-				</ul>
-				<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/HP/Silver" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">HP/Silver</a></center>
-			</ul></ul></ul>
-			<br><br>
-			<table>
-				<tbody>
-					<tr>
-						<td style="width:50px">
-							<center>
-								<img src="https://static.igem.org/mediawiki/2016/8/87/Toulouse_France_MedOr.png" style="width:100%;" />
-							</center>
-						</td>
-						<td colspan="3">
-							<ul><h3><strong>Gold medal</strong></h3></ul>
-						</td>
-					</tr>
-				</tbody>
-			</table>
-			<ul><ul><ul>
-				<ul align="justify" style="font-size:15px;">
-					<li>Innovative human practices: </li>
-						<ul>
-							<strong>-</strong> Active participating in <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Engagement">ExpoScience international</a>??? <a target="blank" href="">exciting perspectives</a><br>
-							<strong>-</strong> Our project is based on a <b>deep</b><a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Human_Practices#Ethics"> Ethical reflection</a><br>
-							<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Attributions#Media">Discussions with people</a> to fit the best with real issue<br>
-							<strong>-</strong> <a target="blank" href="https://2015.igem.org/Team:Toulouse_France/Engagement">Communication with kids</a><br>
-						</ul>
-					<li>Integrated innovative human practices: integration of discussions with Lascaux Cave experts and deep ethical reflection helped by an ethicist into our project</li>
-					<li>Improve the function of the existing pSB0K-mini plasmid <a href="http://parts.igem.org/Part:BBa_K823026">(Biobrick BBa_K823026)</a>, from the 2012 Munich team, in a smaller plasmid pSB0K-mini <a href="http://parts.igem.org/Part:BBa_K1937001">(Biobrick BBa_ K1937001)</a> and enter it in the Registry</li>
-					<li><a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Collaborations">Collaborations:</a> </li>
-					<ul>
-						<strong>-</strong> Creation on our own initiative of <b>Multilanguage protocol videos</b> with the help of 7 iGEM teams for the soundtracks<a target="blank" href=""> ednfhjzel <a target="blank" href=""> <br>
-						<strong>-</strong> <a target="blank" href="https://2016.igem.org/Team:Imperial_College/Software#mainContent">Imperial College team:</a> we studied the optimal growth conditions of <i>B. subtilis</i> and <i>E. coli</i> strains to document their software <b>A.L.I.C.E.</b><br>
-					</ul>
-				</ul>
-				<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/HP/Gold" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">HP/Gold</a></center>
-				<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/Integrated_Practices" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">Integrated Pracices</a></center>
-				<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/Engagement" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">Public Engagement</a></center>
-			</ul></ul></ul>
-			<br><br>
-		</div>
-	</div>
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