Difference between revisions of "Team:Toulouse France"

 
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<font color="white"><p style="text-align:center; font-size:18px; vertical-align:middle;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i>
 
<font color="white"><p style="text-align:center; font-size:18px; vertical-align:middle;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i>
 
<br><br> Back to the origins<br><br><p></font>
 
<br><br> Back to the origins<br><br><p></font>
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<br>What if iGEM stepped 18,000 years back?  
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<br><b style="font-size:18px;">What if iGEM stepped 18,000 years back? </b>
<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency. <br>
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<br><br>At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency. <br>
 
<br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.
 
<br><br>At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered <i>Bacillus subtilis</i> strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.
 
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<h3><strong>Achievements</strong></h3>
 
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<img src="https://static.igem.org/mediawiki/2016/8/88/Toulouse_France_MedBronze.png" style="width:100%;" />
 
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<td colspan="3">
 
<ul><h3><strong>Bronze medal</strong></h3></ul>
 
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<li>We registered the team to iGEM, had fun during the all summer and attended the Giant Jamboree with smiles</li>
 
<li>We successfully submitted<a target="blank" href="https://igem.org/2016_Judging_Form?id=1937"> the Judging form</a></li>
 
<li>A page in the wiki with attributions to every people that helped us in any ways have been created</li>
 
<li>We documented 10 new BioBricks and added it to the registry
 
<br>Registry (from <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Composite_parts"> See Parts</a>)</li>
 
<li>We created and shared a complete description of the team’s project in the Wiki</li>
 
<li>In the <a target="blank" href="https://2016.igem.org/Team:Toulouse_France/Attributions"> attributions:</a> section, we thank all the persons who made
 
this project possible by helping us in different ways and we are very grateful</li>
 
<li>And for sure, we will present to you a beautiful poster and our most pleasant Prezi presentation at the Giant Jamboree!</li>
 
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<td style="width:50px">
 
<center>
 
<img src="https://static.igem.org/mediawiki/2016/1/15/Toulouse_France_MedArgent.png" style="width:100%;" />
 
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</td>
 
 
<td colspan="3">
 
<ul><h3><strong>Silver medal</strong></h3></ul>
 
</td>
 
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</tbody>
 
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<ul><ul><ul>
 
<ul align="justify" style="font-size:15px;">
 
<li>During this project, our commitment for the Human Practices was very strong as we participated in different events in France for <b>Science Popularization</b>, in <b>Education</b> we developed an education kit and protocol videos, we minimized the risks of incidents in the lab for <b>Safety</b>, and in <b>Ethics</b> we created a theatre play</li>
 
<li>We experimentally validated eight new BioBricks and three of them worked successfully as expected</li>
 
<li>We also took part to active collaborations for the scientific community with the initiation and piloting of a seven iGEM teams joined in an effort to create a <b>Multilanguage protocol videos</b></li>
 
</ul>
 
 
<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/HP/Silver" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">HP/Silver</a></center>
 
 
</ul></ul></ul>
 
<br><br>
 
 
 
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<tbody>
 
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<td style="width:50px">
 
<center>
 
<img src="https://static.igem.org/mediawiki/2016/8/87/Toulouse_France_MedOr.png" style="width:100%;" />
 
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</td>
 
 
<td colspan="3">
 
<ul><h3><strong>Gold medal</strong></h3></ul>
 
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<li>Integrated innovative human practices: we soon realized that using GMOs in such an unstable ecosystem as the Lascaux cave was a risky challenge. Our project was therefore designed from the many discussions we had with the cave curators, scientists working in laboratory caves, policy makers and the public</li>
 
<li>We successfully took-up the challenge to improve the only replicative plasmid for <i>B. subtilis</i> mentioned in the registry, pSBBS0K-P <a href="http://parts.igem.org/Part:BBa_K823026">(Biobrick BBa_K823026)</a>, to create a lighter version. We even went further from this plasmid by creating and validating a part to turn any pSB1C3 plasmid in a replicative plasmid for <i>B. subtilis</i>: : <a href="http://parts.igem.org/Part:BBa_K1937002">pSB1C3-OriKan (BBa_K1937002)</a></li>
 
 
</ul>
 
<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/HP/Gold" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">HP/Gold</a></center>
 
<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/Integrated_Practices" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">Integrated Pracices</a></center>
 
<center><a class="button-home" href="https://2016.igem.org/Team:Toulouse_France/Engagement" style="border: 1px solid #282828;-webkit-border-radius: 5px;-moz-border-radius: 5px;border-radius: 5px; padding: 5px 15px; color: #282828; text-decoration: none; font-size: 17px; background: none; display: block; width: 200px;">Public Engagement</a></center>
 
 
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Latest revision as of 20:11, 19 October 2016

iGEM Toulouse 2016


iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave

Back to the origins


What if iGEM stepped 18,000 years back?

At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that causes colored spots on the frescoes. Nowadays, mechanical and chemical solutions are monthly used and the cave is still in danger due to their limited efficiency.


At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an engineered Bacillus subtilis strain which grow on bacterial organisms present in the cave. It releases antifungals when in close viscinity of fungi. Since we care about environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent DNA transmission and a physical device was designed to confine our strain.




Contacts