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− | <tspan x="500" y="600">Inflamed area of colon epithelium - in case of ulcerative </tspan>
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− | <tspan x="500" y="630">colitis parts of colon and rectum are inflamed because </tspan>
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− | <tspan x="500" y="660">of an autoimmune reaction.</tspan>
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− | <title
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− | id="title5229">zellen</title>
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− | <tspan x="500" y="660">them a perfect target for our project. </tspan>
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− | <tspan x="500" y="600">Carrier - Using the endospores of Bacillus subtilis as a</tspan>
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− | <tspan x="500" y="630">carrier we receive a tool with multivalency. This increases</tspan>
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− | <tspan x="500" y="660"> the specificity of binding to diseased tissue in comparison</tspan>
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− | <tspan x="500" y="690">to healthy tissue where CEA is expressed in low concentration.</tspan>
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− | <tspan x="500" y="720">To gain multivalency a carrier is used.</tspan>
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| |
− | <tspan x="500" y="600">Drug Delivery - Glutathione-S-Transferase is an</tspan>
| |
− | <tspan x="500" y="630">enzyme that is responsible for several detoxification reactions</tspan>
| |
− | <tspan x="500" y="660">in the liver. We use it locally to convert an inactive prodrug</tspan>
| |
− | <tspan x="500" y="690">into the active drug. </tspan>
| |
| | | |
| + | <a target="_blank" style="color: #66ccff" href="https://2016.igem.org/Team:Freiburg/Binding">Roses are red violets are blue I am just a nanobody waiting for you</a> |
| + | <br> |
| + | <br> |
| + | |
| + | <a target="_blank" style="color: #66ccff" href="https://2016.igem.org/Team:Freiburg/Delivery">They call themselves the "Delivery Boys"</a> |
| + | <br> |
| + | <br> |
| + | |
| + | <a target="_blank" style="color: #66ccff" href="https://2016.igem.org/Team:Freiburg/Production_Nanocillus"> A new hope </a> |
| + | <br> |
| + | <br> |
| + | |
| + | <a target="_blank" style="color: #66ccff" href="https://2016.igem.org/Team:Freiburg/Biobricks"> |
| + | Not just another brick in the wall </a> |
| + | <br> |
| + | <br> |
| + | |
| + | <a target="_blank" style="color: #66ccff" href="https://2016.igem.org/Team:Freiburg/Shampoo"> Click for a frothy surprise </a> |
| + | <br> |
| + | <br> |
| | | |
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