Difference between revisions of "Team:NJU-China"

 
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         <ul id="dropdown1" class="dropdown-content">
 
         <ul id="dropdown1" class="dropdown-content">
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Target_Module">Target Module</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Targeting_Module">Targeting Module</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
         </ul>
 
         </ul>
 
         <ul id="dropdown2" class="dropdown-content">
 
         <ul id="dropdown2" class="dropdown-content">
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             <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vitro">in vitro</a></li>
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            <li><a href="https://2016.igem.org/Team:NJU-China/Results">Parts</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vivo">in vivo</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Validations">Validations</a></li>
 +
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Safety">Safety</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
         </ul>
 
         </ul>
 
         <ul id="dropdown3" class="dropdown-content">
 
         <ul id="dropdown3" class="dropdown-content">
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Methods">Methods</a></li>
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             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
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            <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">protocol</a></li>
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                    <a href="#" data-activates="nav-mobile" class="button-collapse"><i class="material-icons">menu</i></a>
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                <ul class="right hide-on-med-and-down">
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                    <ul class="right hide-on-med-and-down">
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Background">Background</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Background">Background</a></li>
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                    <li><a class="dropdown-button" href="#!" data-activates="dropdown1">Project Design</a></li>
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                        <li><a class="dropdown-button" href="#!" data-activates="dropdown1">Project Design</a></li>
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                        <!-- Dropdown Trigger -->
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Modeling">Modeling</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Modeling">Modeling</a></li>
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                    <li><a class="dropdown-button" href="#!" data-activates="dropdown2">Results</a></li>
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                        <li><a class="dropdown-button" href="#!" data-activates="dropdown2">Results</a></li>
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Human_Practices">Human Practice</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Human_Practices">Human Practice</a></li>
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Team">Team</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Team">Team</a></li>
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Attributions">Attributions</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Attributions">Attributions</a></li>
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                    <li><a href="https://2016.igem.org/Team:NJU-China/Collaborations">Collaborations</a></li>
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                        <li><a href="https://2016.igem.org/Team:NJU-China/Collaborations">Collaborations</a></li>
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                    <li><a class="dropdown-button" href="#!" data-activates="dropdown3">Notebook</a></li>
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                        <li><a class="dropdown-button" href="#!" data-activates="dropdown3">Notebook</a></li>
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                </ul>
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                        <a href="https://2016.igem.org/Team:NJU-China"><img class="background responsive-img" src="https://static.igem.org/mediawiki/2016/c/c8/NJU_China_2016_iGEM_logo.png" alt="NJU-China LOGO"></a>
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                            <img class="background responsive-img" src="https://static.igem.org/mediawiki/2016/c/c8/NJU_China_2016_iGEM_logo.png" alt="NJU-China LOGO"> </li>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Background" class="waves-effect waves-teal">Background</a></li>
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                                <li class="bold"> <a class="collapsible-header waves-effect waves-teal">Project Design</a>
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                            <li class="bold"> <a class="collapsible-header waves-effect waves-teal">Project Design</a>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design">RNAi Module</a></li>
−
                                            <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Target_Module">Target Module</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Targeting_Module">Targeting Module</a></li>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
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                                        </ul>
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                                    </ul>
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                            </ul>
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                        </li>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Modeling" class="waves-effect waves-teal">Modeling</a></li>
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                    <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Modeling" class="waves-effect waves-teal">Modeling</a></li>
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                                <li class="bold"> <a class="collapsible-header waves-effect waves-teal">Results</a>
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                            <li class="bold"> <a class="collapsible-header waves-effect waves-teal">Results</a>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vitro">in vitro</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Results">Parts</a></li>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vivo">in vivo</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Results#Validations">Validations</a></li>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Results#Safety">Safety</a></li>
−
                                        </ul>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
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                                    </div>
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                                    </ul>
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                                </li>
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                            </ul>
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                        </li>
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                        </ul>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Human_Practices" class="waves-effect waves-teal">Human Practices</a></li>
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                    </li>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Team" class="waves-effect waves-teal">Team</a></li>
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                    <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Human_Practices" class="waves-effect waves-teal">Human Practices</a></li>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Attributions" class="waves-effect waves-teal">Attributions</a></li>
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                    <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Team" class="waves-effect waves-teal">Team</a></li>
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                        <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Collaborations" class="waves-effect waves-teal">Collaborations</a></li>
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                    <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Attributions" class="waves-effect waves-teal">Attributions</a></li>
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                        <li class="bold no-padding">
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                    <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Collaborations" class="waves-effect waves-teal">Collaborations</a></li>
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                                <li class="bold"> <a class="collapsible-header waves-effect waves-teal">Notebook</a>
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                                <div class="collapsible-body">
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
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                                    <ul>
−
                                            <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Methods">Methods</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
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                                            <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
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                                        <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
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                                        </ul>
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                                    </ul>
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                 <li onclick="$('html, body').animate({ scrollTop: 0 }, 'fast');"><a class="btn-floating green tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Top"><i class="material-icons">arrow_upward</i></a></li>
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                 <li onclick="$('html, body').animate({scrollTop: $('html').height()-$(window).height()}, 'fast')"><a class="btn-floating yellow darken-2 tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Bottom"><i class="material-icons">arrow_downward</i></a></li>
 
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                 <li><a class="btn-floating blue button-collapse hide-on-large-only tooltipped" data-position="left" data-delay="50" data-tooltip="Show Navigation" data-activates="nav-mobile"><i class="material-icons">menu</i></a></li>
 
                 <li><a class="btn-floating blue button-collapse hide-on-large-only tooltipped" data-position="left" data-delay="50" data-tooltip="Show Navigation" data-activates="nav-mobile"><i class="material-icons">menu</i></a></li>
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                     <div class="card red lighten-2 z-depth-3">
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                         <div class="card-content white-text">
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                         <div class="card-content">
 
                             <span class="card-title">
 
                             <span class="card-title">
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                                 Say goodbye to Mr. Tumor: targeted therapy for cancer based on siRNA-exosome drug system
+
                                 Goodbye, Mr. Tumor
 
                             </span>
 
                             </span>
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                            <div class="divider"></div>
 
 
                             <p>Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.</p>
 
                             <p>Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.</p>
 
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         </div>
 
     </main>
 
     </main>
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    <footer class="page-footer">
 
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        <div class="container">
 
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−
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                    <h5 class="white-text">Acknowledgement</h5>
 
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                    <p class="grey-text text-lighten-4">We would like to express our most sincere gratitude to every person and institute that helped us during this whole project.</p>
 
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                </div>
 
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                    <h5 class="white-text">Links</h5>
 
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        </div>
 
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        <div class="footer-copyright">
 
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−
    <!-- 理论上应用 2.1.4 版本的 jQuery，但是iGEM官方提供 1.11.1 -->
 
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    <!-- <script src="https://2016.igem.org/Team:NJU-China/mdlib/jquery214?action=raw&amp;ctype=text/javascript"></script> -->
 
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    <!-- 自己上传的jQuery 1.11.1 -->
 
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    <!-- <script src="https://2016.igem.org/Team:NJU-China/lib/jquery?action=raw&amp;ctype=text/javascript"></script> -->
 
 
     <script src="https://2016.igem.org/Team:NJU-China/mdlib/mdjs?action=raw&amp;ctype=text/javascript"></script>
 
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        // Initialize collapsible (uncomment the line below if you use the dropdown variation)
 
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        $('.collapsible').collapsible();
 
 
         // Initialize carousel
 
         // Initialize carousel
 
         $('.carousel.carousel-slider').carousel({
 
         $('.carousel.carousel-slider').carousel({
 +
            time_constant: 400,
 
             full_width: true,
 
             full_width: true,
 
             indicators: true,
 
             indicators: true,
 
         });
 
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        // auto play the carousel
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        let x = 9 * $('.carousel').width() / 16;
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        // Initialize collapse button
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        // Initialize collapsible (uncomment the line below if you use the dropdown variation)
 +
        $('.collapsible').collapsible();
 
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Latest revision as of 03:33, 20 October 2016

add
Goodbye, Mr. Tumor

Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.