Difference between revisions of "Team:NJU-China"

m
 
(39 intermediate revisions by the same user not shown)
Line 21: Line 21:
 
     nav ul li.active {
 
     nav ul li.active {
 
         background-color: unset;
 
         background-color: unset;
 +
    }
 +
   
 +
    nav>div>ul.right>li>a:visited {
 +
        color: white;
 
     }
 
     }
 
     </style>
 
     </style>
Line 30: Line 34:
 
         <ul id="dropdown1" class="dropdown-content">
 
         <ul id="dropdown1" class="dropdown-content">
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
−
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Target_Module">Target Module</a></li>
+
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Targeting_Module">Targeting Module</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
         </ul>
 
         </ul>
 
         <ul id="dropdown2" class="dropdown-content">
 
         <ul id="dropdown2" class="dropdown-content">
−
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vitro">in vitro</a></li>
+
            <li><a href="https://2016.igem.org/Team:NJU-China/Results">Parts</a></li>
−
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vivo">in vivo</a></li>
+
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Validations">Validations</a></li>
 +
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Safety">Safety</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
         </ul>
 
         </ul>
 
         <ul id="dropdown3" class="dropdown-content">
 
         <ul id="dropdown3" class="dropdown-content">
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
 
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
−
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Methods">Methods</a></li>
+
             <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
−
            <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">protocol</a></li>
+
 
         </ul>
 
         </ul>
 
         <nav>
 
         <nav>
Line 63: Line 67:
 
                 <ul id="nav-mobile" class="side-nav">
 
                 <ul id="nav-mobile" class="side-nav">
 
                     <li class="logo">
 
                     <li class="logo">
−
                         <img class="background responsive-img" src="https://static.igem.org/mediawiki/2016/c/c8/NJU_China_2016_iGEM_logo.png" alt="NJU-China LOGO"> </li>
+
                         <a href="https://2016.igem.org/Team:NJU-China"><img class="background responsive-img" src="https://static.igem.org/mediawiki/2016/c/c8/NJU_China_2016_iGEM_logo.png" alt="NJU-China LOGO"></a>
 +
                    </li>
 
                     <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Background" class="waves-effect waves-teal">Background</a></li>
 
                     <li class="bold"><a href="https://2016.igem.org/Team:NJU-China/Background" class="waves-effect waves-teal">Background</a></li>
 
                     <li class="bold no-padding">
 
                     <li class="bold no-padding">
Line 70: Line 75:
 
                                 <div class="collapsible-body">
 
                                 <div class="collapsible-body">
 
                                     <ul>
 
                                     <ul>
−
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#RNAi_Module">RNAi Module</a></li>
+
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design">RNAi Module</a></li>
−
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Target_Module">Target Module</a></li>
+
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Targeting_Module">Targeting Module</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Project_Design#Assembly">Assembly</a></li>
 
                                     </ul>
 
                                     </ul>
Line 84: Line 89:
 
                                 <div class="collapsible-body">
 
                                 <div class="collapsible-body">
 
                                     <ul>
 
                                     <ul>
−
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vitro">in vitro</a></li>
+
                                        <li><a href="https://2016.igem.org/Team:NJU-China/Results">Parts</a></li>
−
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#in_vivo">in vivo</a></li>
+
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#Validations">Validations</a></li>
 +
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#Safety">Safety</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Results#Conclusions">Conclusions</a></li>
 
                                     </ul>
 
                                     </ul>
Line 102: Line 108:
 
                                     <ul>
 
                                     <ul>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Calendar">Calendar</a></li>
−
                                        <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Methods">Methods</a></li>
 
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
 
                                         <li><a href="https://2016.igem.org/Team:NJU-China/Notebook/Protocol">Protocol</a></li>
 
                                     </ul>
 
                                     </ul>
Line 120: Line 125:
 
             </a>
 
             </a>
 
             <ul>
 
             <ul>
−
                 <li onclick="$('html, body').animate({ scrollTop: 0 }, 'slow');"><a class="btn-floating green tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Top"><i class="material-icons">vertical_align_top</i></a></li>
+
                 <li onclick="$('html, body').animate({ scrollTop: 0 }, 'fast');"><a class="btn-floating green tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Top"><i class="material-icons">arrow_upward</i></a></li>
−
                 <li onclick="$('html, body').animate({scrollTop: $('html').height()-$(window).height()}, 'slow')"><a class="btn-floating yellow darken-2 tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Bottom"><i class="material-icons">vertical_align_bottom</i></a></li>
+
                 <li onclick="$('html, body').animate({scrollTop: $('html').height()-$(window).height()}, 'fast')"><a class="btn-floating yellow darken-2 tooltipped" data-position="left" data-delay="50" data-tooltip="Scroll to Bottom"><i class="material-icons">arrow_downward</i></a></li>
 
                 <li onclick="$(this).parent().parent().hide('slow')"><a class="btn-floating purple darken-3"><i class="close material-icons tooltipped" data-position="left" data-delay="50" data-tooltip="Hide FAB">close</i></a></li>
 
                 <li onclick="$(this).parent().parent().hide('slow')"><a class="btn-floating purple darken-3"><i class="close material-icons tooltipped" data-position="left" data-delay="50" data-tooltip="Hide FAB">close</i></a></li>
 
                 <li><a class="btn-floating blue button-collapse hide-on-large-only tooltipped" data-position="left" data-delay="50" data-tooltip="Show Navigation" data-activates="nav-mobile"><i class="material-icons">menu</i></a></li>
 
                 <li><a class="btn-floating blue button-collapse hide-on-large-only tooltipped" data-position="left" data-delay="50" data-tooltip="Show Navigation" data-activates="nav-mobile"><i class="material-icons">menu</i></a></li>
Line 130: Line 135:
 
             <div class="section">
 
             <div class="section">
 
                 <div class="carousel carousel-slider z-depth-1">
 
                 <div class="carousel carousel-slider z-depth-1">
−
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/a/a2/NJU_China_2016_test_1.jpg"></a>
+
                    <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/c/c7/NJU_China_2016_iGEM_Home_1.jpg"></a>
−
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/0/06/NJU_China_2016_test_2.jpg"></a>
+
                    <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/0/00/NJU_China_2016_iGEM_Home_2.JPG"></a>
−
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/c/cb/NJU_China_2016_test_3.jpg"></a>
+
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/a/a2/NJU_China_2016_iGEM_Home_3.jpg"></a>
−
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/f/f5/NJU_China_2016_test_4.jpg"></a>
+
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/a/a9/NJU_China_2016_iGEM_Home_4.jpg"></a>
 +
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/5/5a/NJU_China_2016_iGEM_Home_5.jpg"></a>
 +
                     <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/c/c6/NJU_China_2016_iGEM_Home_6.JPG"></a>
 +
                    <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/8/81/NJU_China_2016_iGEM_Home_7.JPG"></a>
 +
                    <a class="carousel-item"><img src="https://static.igem.org/mediawiki/2016/1/14/NJU_China_2016_iGEM_Home_8.jpg"></a>
 
                 </div>
 
                 </div>
 
             </div>
 
             </div>
 
             <div class="section">
 
             <div class="section">
 
                 <div class="row">
 
                 <div class="row">
−
                     <div class="card teal lighten-1 z-depth-3">
+
                     <div class="card z-depth-1" style="background-color: #fdeb9c">
−
                         <div class="card-content white-text">
+
                         <div class="card-content">
 
                             <span class="card-title">
 
                             <span class="card-title">
−
                                 Say goodbye to Mr. Tumor: targeted therapy for cancer based on siRNA-exosome drug system
+
                                 Goodbye, Mr. Tumor
 
                             </span>
 
                             </span>
−
                            <div class="card-action">
 
−
                                <a class="waves-effect waves-dark btn teal accent-4"><i class="material-icons left">vpn_key</i>Keyword 1</a>
 
−
                                <a class="waves-effect waves-dark btn teal accent-4"><i class="material-icons left">vpn_key</i>Keyword 2</a>
 
−
                                <a class="waves-effect waves-dark btn teal accent-4"><i class="material-icons left">vpn_key</i>Keyword 3</a>
 
−
                            </div>
 
 
                             <p>Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.</p>
 
                             <p>Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.</p>
 
                         </div>
 
                         </div>
Line 155: Line 159:
 
         </div>
 
         </div>
 
     </main>
 
     </main>
−
    <footer class="page-footer">
 
−
        <div class="container">
 
−
            <div class="row">
 
−
                <div class="col l6 s12">
 
−
                    <h5 class="white-text">Acknowledgement</h5>
 
−
                    <p class="grey-text text-lighten-4">We would like to express our most sincere gratitude to every person and institute that helped us during this whole project.</p>
 
−
                </div>
 
−
                <div class="col l4 offset-l2 s12">
 
−
                    <h5 class="white-text">Links</h5>
 
−
                    <ul>
 
−
                        <li> <a class="grey-text text-lighten-3" href=""><img src="" alt=""></a> </li>
 
−
                        <li> <a class="grey-text text-lighten-3" href=""><img src="" alt=""></a> </li>
 
−
                        <li> <a class="grey-text text-lighten-3" href=""><img src="" alt=""></a> </li>
 
−
                        <li> <a class="grey-text text-lighten-3" href=""><img src="" alt=""></a> </li>
 
−
                    </ul>
 
−
                </div>
 
−
            </div>
 
−
        </div>
 
−
        <div class="footer-copyright">
 
−
            <div class="container">
 
−
                2016 iGEM NJU-China
 
−
            </div>
 
−
        </div>
 
−
    </footer>
 
−
    <!-- 理论上应用 2.1.4 版本的 jQuery，但是iGEM官方提供 1.11.1 -->
 
−
    <!-- jQuery 2.1.4 -->
 
−
    <!-- <script src="https://2016.igem.org/Team:NJU-China/mdlib/jquery214?action=raw&amp;ctype=text/javascript"></script> -->
 
−
    <!-- 自己上传的jQuery 1.11.1 -->
 
−
    <!-- <script src="https://2016.igem.org/Team:NJU-China/lib/jquery?action=raw&amp;ctype=text/javascript"></script> -->
 
 
     <script src="https://2016.igem.org/Team:NJU-China/mdlib/mdjs?action=raw&amp;ctype=text/javascript"></script>
 
     <script src="https://2016.igem.org/Team:NJU-China/mdlib/mdjs?action=raw&amp;ctype=text/javascript"></script>
 
     <script type="text/javascript">
 
     <script type="text/javascript">
 
     $("document").ready(function() {
 
     $("document").ready(function() {
−
        // Initialize collapse button
 
−
        $(".button-collapse").sideNav();
 
−
        // Initialize collapsible (uncomment the line below if you use the dropdown variation)
 
−
        $('.collapsible').collapsible();
 
 
         // Initialize carousel
 
         // Initialize carousel
 
         $('.carousel.carousel-slider').carousel({
 
         $('.carousel.carousel-slider').carousel({
 +
            time_constant: 400,
 
             full_width: true,
 
             full_width: true,
 
             indicators: true,
 
             indicators: true,
 
         });
 
         });
 +
        // auto play the carousel
 +
        window.setInterval(function() {
 +
            $('.carousel').carousel('next')
 +
        }, 4000);
 +
        let x = 9 * $('.carousel').width() / 16;
 +
        $('.carousel').height(x);
 +
        // Initialize collapse button
 +
        $(".button-collapse").sideNav();
 +
        // Initialize collapsible (uncomment the line below if you use the dropdown variation)
 +
        $('.collapsible').collapsible();
 
     })
 
     })
 +
    $(window).resize(function() {
 +
        let x = 0.5 * $('.carousel').width();
 +
        $('.carousel').height(x);
 +
    });
 
     </script>
 
     </script>
 
</body>
 
</body>
  
 
</html>
 
</html>

Latest revision as of 03:33, 20 October 2016

add
Goodbye, Mr. Tumor

Cancers, as the most frightening death threats, are aggressive and malignant. However, a perfect treatment of cancer has not appeared so far. The goal of our project is to develop a strategy to treat cancers, with building a transplantable drug system targeting a specific molecule that functions in cancer. We packed siRNA into exosomes (nano-sized vesicles secreted by human cells) to deliver our drug into certain part of a patient's body. Then we modified our exosome with iRGD to act as integrin-specific targeting tool. Our validation experiments will be carried out at the level of cells and animals to prove both the targeting and silencing function of this drug. Eventually, we expect to see a specific accumulation of the siRNA in the mice’s tumor tissues and the decreased expression of the oncogenes at the transcription level. This project may provide new insights into future treatment of cancer.