Difference between revisions of "Team:Pasteur Paris"

 
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<h1><center><span class="cursive">A biosilica-based detection device</span><span>for (re)emerging arboviral infectious diseases</span></center></h1>
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<h1><B>MOS(KIT)O</B> <span>A biosilica-based detection device </br>for (re)emerging arboviral infectious diseases</span></h1>
  
  
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<img src="https://static.igem.org/mediawiki/2016/4/46/ARBOVIRUS_PROPA.png" alt="" width="640" height="310" /><figcaption>  The global distribution of arboviruses. </figure><!--
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<img src="https://static.igem.org/mediawiki/2016/8/8a/T--Pasteur_Paris--Arbovirus_map.png" alt="" width="640" height="310" /><figcaption>  The global distribution of arboviruses. </figure><!--
 
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<img src="https://static.igem.org/mediawiki/2016/2/22/INSECTICIDES.png" alt="" width="640" height="310" /><figcaption> The massive use of insecticides causes resistance in mosquitoes.</figcaption>
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<img src="https://static.igem.org/mediawiki/2016/d/dc/T--Pasteur_Paris--INSECTICIDES.jpg" alt="" width="640" height="310" /><figcaption> The massive use of insecticides causes resistance in mosquitoes.</figcaption>
 
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<img src="https://static.igem.org/mediawiki/2016/3/32/Team.png" alt="" width="640" height="310" />
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<img src="https://static.igem.org/mediawiki/2016/f/f0/T--Pasteur_Paris--Team.png" alt="" width="640" height="310" />
 
<figcaption>After many brainstorming sessions and after an exhaustive literature search...</figcaption>
 
<figcaption>After many brainstorming sessions and after an exhaustive literature search...</figcaption>
 
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<img src="https://static.igem.org/mediawiki/2016/0/0d/Our_project.png" alt="" width="640" height="310" />
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<img src="https://static.igem.org/mediawiki/2016/5/5f/T--Pasteur_Paris--Our_project.png" alt="" width="640" height="310" />
 
<figcaption>MOS(KIT)O emerged!! </figcaption>
 
<figcaption>MOS(KIT)O emerged!! </figcaption>
 
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<h2><B>Abstract</span></B></h2>
  
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<FONT size "25px"><p><B>Vector-borne (re) emerging diseases</B> are responsible for severe epidemics worldwide. In most cases, vaccines or treatments are not available, and insecticides are the primary source for vector control. Consequently, <B>over-spraying of insecticides</B> impacts the environment and leads to the selection of insecticide-<B>resistant mosquitoes</B>. Therefore, we developed a novel diagnostic device, <B>Mos(kit)o</B>, that includes a fixed or mobile mosquito trap and a <B>biosilica cellulose composite patch</B> from genetically modified <i>E. coli</i> bacteria. The design of the patch creates a <B>multilayered matrix</B> coated with antibodies able to detect a wide panel of vector-borne pathogens and insecticide-resistant proteins from captured mosquitoes. Additionally, the patch will have 2D barcoded readouts, generating an environmental <B>surveillance database</B>. A precise map of vector hot spots will provide a better assessment and response to vector-borne diseases, assisting local health authorities with <B>anticipating</B> and preparing for an epidemic. Our tool will be <B>user-friendly</B>, <B>safe</B>, and <B>applicable</B>.</p></FONT>
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<div class=text3>
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<p>
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</br></br></br></br>
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<B></a>MOS(KIT)O in the press</br>
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<a href="http://www.lemonde.fr/sciences/article/2016/11/14/la-biologie-synthetique-fait-son-casting_5030987_1650684.html">Le monde</a></br>
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<a href="http://www.makery.info/2016/11/08/ligem-recompense-le-kit-moskito-des-etudiants-pour-linstitut-pasteur/">Makery</a></br>
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<a href="http://frenchculture.org/visual-and-performing-arts/news/moskito-wins-four-awards-igem-2016-championship-boston">French embassy in the United States</a></br>
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<a href="https://www.france-science.org/iGEM-la-biologie-de-synthese-dans.html">Office for Science & Technology at the Embassy of France in the United States</a></br>
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<a href="http://www.di2c.u-psud.fr/evenements/evenement/victoire-des-etudiants-du-m1-pidn-promo-2015-2016-a-la-competition-igem-organisee-a-boston">University of Paris Saclay</a></br>
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<a href="http://www.etsl.fr/accueil.html">Laboratory Techniques school</a></br></B>
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<B><a href="http://www.pasteur.fr/igem">iGEM at Institut Pasteur</a></B></br></br></br></br>
  
  
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Latest revision as of 16:21, 1 December 2016