Difference between revisions of "Team:TU Darmstadt"

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<h2> Welcome to iGEM 2016! </h2>
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    <h2> iGEM TU Darmstadt 2016</h2>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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     <h3>Project Description</h3>
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     <h3>Glow before you go (working title)</h3>
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     <p>Hier Text einsetzen....</p>
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        The critical evaluation of the project’s safety is required from each iGEM Team participating in the competition. Therefore the iGEM HQ created an entire subpage on their website where the teams can find all the necessary information, such as risk levels or general safety requirements. Unfortunately there is no chance to look up complete, working safety approaches from previous teams.
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        <i>
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        It should be easy for teams to choose a well characterized safety approach which is suitable for their own project out of a catalog and directly see how to easily incorporate it. Our project is supposed to lead the way into that direction.
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        </i>
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        In our 2016 project we focus on easily enabling teams to work safely with <i>E.coli</i>. By integrating genetic circuits into the <i>E.coli</i> genome we ensure that genetically modified bacteria cannot survive outside of the required lab with the particular conditions they need. The genetic circuit is based on the availability of an unnatural amino acid (UAA) and is regulated within two steps:
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            <li>When the concentration of the unnatural amino acid is low a reporter protein is expressed which signalizes the low level of UAA.</li>
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            <li>When the UAA concentration reaches zero (which is also the case if bacteria get out of the lab) the expression of colic in is induced which then kills the bacteria.</li>
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        </ol>
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     <p>
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        Additionally we hope to facilitate and accelerate the molecular cloning process of DNA through a new standard based on the RFC10 standard. We use riboswitches to show a successful ligation without additional testing procedures.
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<h5>Before you start: </h5>
 
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<p> Please read the following pages:</p>
 
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<li>  <a href="https://2016.igem.org/Requirements">Requirements page </a> </li>
 
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<li> <a href="https://2016.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
 
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<li> <a href="https://2016.igem.org/Resources/Template_Documentation"> Template Documentation </a></li>
 
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<h5> Styling your wiki </h5>
 
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
 
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
 
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<h5> Wiki template information </h5>
 
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
 
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<h5> Editing your wiki </h5>
 
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
 
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<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> Click here to edit this page! </a></p>
 
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<h5>Tips</h5>
 
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
 
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<li>Be clear about what you are doing and how you plan to do this.</li>
 
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
 
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
 
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
 
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
 
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<li>Have lots of fun! </li>
 
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<h5>Inspiration</h5>
 
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
 
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
 
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
 
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
 
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
 
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
 
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
 
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<h5> Uploading pictures and files </h5>
 
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<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
 
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
 
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Revision as of 09:07, 27 June 2016

MENU ▤

iGEM TU Darmstadt 2016

Glow before you go (working title)

The critical evaluation of the project’s safety is required from each iGEM Team participating in the competition. Therefore the iGEM HQ created an entire subpage on their website where the teams can find all the necessary information, such as risk levels or general safety requirements. Unfortunately there is no chance to look up complete, working safety approaches from previous teams. It should be easy for teams to choose a well characterized safety approach which is suitable for their own project out of a catalog and directly see how to easily incorporate it. Our project is supposed to lead the way into that direction. In our 2016 project we focus on easily enabling teams to work safely with E.coli. By integrating genetic circuits into the E.coli genome we ensure that genetically modified bacteria cannot survive outside of the required lab with the particular conditions they need. The genetic circuit is based on the availability of an unnatural amino acid (UAA) and is regulated within two steps:

  1. When the concentration of the unnatural amino acid is low a reporter protein is expressed which signalizes the low level of UAA.
  2. When the UAA concentration reaches zero (which is also the case if bacteria get out of the lab) the expression of colic in is induced which then kills the bacteria.

Additionally we hope to facilitate and accelerate the molecular cloning process of DNA through a new standard based on the RFC10 standard. We use riboswitches to show a successful ligation without additional testing procedures.