iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave
Back to the origins
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− | <p style="text-align:center; font-size:18px;">iGEM Toulouse Team presents | + | <p style="text-align:center; font-size:18px;">iGEM Toulouse Team presents<br><i>Paleotilis, a shield for the Lascaux cave</i></p> |
<p style="text-align:center; font-size:18px;">Back to the origins<br><br><p> | <p style="text-align:center; font-size:18px;">Back to the origins<br><br><p> | ||
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+ | What if iGEM stepped 18,000 years back? <br> | ||
+ | At that time, cavemen painted extraordinary frescoes on the Lascaux cave (France). The cave remained stable until its discovery in 1940, | ||
+ | which deeply disturbed its ecosystem. It was closed shortly after mainly because of contamination by fungi that cause colored spots on | ||
+ | the frescoes.Nowadays, mechanical and chemical solutions are daily used and the cave is still in danger due to their limited efficiency. | ||
+ | <br> | ||
+ | At iGEM Toulouse, we thought about an innovative biological solution based on the last advances in synthetic biology. It consists in an | ||
+ | engineered <i>Bacillus subtilis</i> bacterium that develops from bacterial organisms present in the cave. It releases antifungals when in close | ||
+ | viscinity of fungi. Since we care about our environment, an inducible riboswitch-based double toxin/antitoxin system was created to prevent | ||
+ | DNA transmission and a physical device was designed to confine our strain. | ||
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+ | </div> | ||
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iGEM Toulouse Team presents
Paleotilis, a shield for the Lascaux cave
Back to the origins
Website by Team iGEM Toulouse 2016