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− | < | + | <h5 class="smallHd">Biosensor</h5> |
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<p>A biosensor is an integrated and autonomous measurement device or system in which a biological element is used for specific stimulus recognition and quantification. This element can be a macro-molecule, an organ or a cell. Here, we use bacteria as the biological element and thus it is a « whole cell biosensor » [1] [3]. A biosensor is composed of a detector element and a reporter element/ The input stimulus will be recognized by the detector, which in turn stimulate the transcription of the reporter gene triggering an output signal.</p> | <p>A biosensor is an integrated and autonomous measurement device or system in which a biological element is used for specific stimulus recognition and quantification. This element can be a macro-molecule, an organ or a cell. Here, we use bacteria as the biological element and thus it is a « whole cell biosensor » [1] [3]. A biosensor is composed of a detector element and a reporter element/ The input stimulus will be recognized by the detector, which in turn stimulate the transcription of the reporter gene triggering an output signal.</p> | ||
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<img src="https://static.igem.org/mediawiki/2016/e/e4/T--Ionis_Paris--BioBiosensorFig1.png" alt=""> | <img src="https://static.igem.org/mediawiki/2016/e/e4/T--Ionis_Paris--BioBiosensorFig1.png" alt=""> | ||
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<p>When using a biosensor, some factors have to be taken in account as they affect the responsiveness of the system. These factors include the choice of host organism, culture medium composition, the growth phase of the harvested bacteria, and the number of bacteria per measurement. It may be possible to improve the performance of biosensors by individually optimizing these factors. [3]</p> | <p>When using a biosensor, some factors have to be taken in account as they affect the responsiveness of the system. These factors include the choice of host organism, culture medium composition, the growth phase of the harvested bacteria, and the number of bacteria per measurement. It may be possible to improve the performance of biosensors by individually optimizing these factors. [3]</p> | ||
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− | <p><b> | + | <p><b>References (Links are provided when available):</b></p> |
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Revision as of 11:28, 17 October 2016
A biosensor is an integrated and autonomous measurement device or system in which a biological element is used for specific stimulus recognition and quantification. This element can be a macro-molecule, an organ or a cell. Here, we use bacteria as the biological element and thus it is a « whole cell biosensor » [1] [3]. A biosensor is composed of a detector element and a reporter element/ The input stimulus will be recognized by the detector, which in turn stimulate the transcription of the reporter gene triggering an output signal. When using a biosensor, some factors have to be taken in account as they affect the responsiveness of the system. These factors include the choice of host organism, culture medium composition, the growth phase of the harvested bacteria, and the number of bacteria per measurement. It may be possible to improve the performance of biosensors by individually optimizing these factors. [3] References (Links are provided when available):Biosensor
What is it ?