1. An Enzyme-Coupled Biosensor Snables (S)-Reticuline Productions in Yeast from Glucose (Nature Chemical Biology. DOI: 10.1038/NCHEMBIO.1816)

1. An Enzyme Coupled Biosensor - Landon Getz and Emma Finlayson-Trick

1. John E. Dueber uses yeast cells to generate (S)-reticuline, an important metabolic step on the pathway to producing morphine. A biosensor coupled to the pathway allows them to detect, via a yellow pigment, how much (L)-DOPA is being produced, which is another metabolite in the pathway. Overall they have suceeded in creating this metabolic pathway in yeast and created a new phentypic marker for synthetic biology

2. DNA-guided genome editing using the Natronobacterium gregoryi Argonaute (Nature Biotechnology. DOI: 10.1038/nbt.3547)

2. DNA-guided Genome Editing using NgArgo

2. Our PI Dr. Cheng and our team member Mackenzie outline a new form of DNA-guided genome editing discovered by Gao et al. According to Gao et al, This technique functions similarly to CRISPR-Cas9 but has some advantages in it's specificity.

3.An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae. (Science. DOI: 10.1126/science.1214547)

3. An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae

3. Description Here.

4. Microbial Sequencing - Emily Lamoureux

4. Microbial Seqeuncing

4. This presentation is not a Journal Club presentation, but it was helpful for our sequencing experiments. Emily gave us an overview of Illumina sequencing and what the bioinformatic pipeline looked like.

5. Microbiome Data Presentation - Landon Getz

5. Shubenacadie Microbiome Survey

5. While not a Journal Club paper, Landon presented the data we collected from our microbiome survey at one of our meetings. This presentation was a rough overview and brainstorm session for our microbiome data.