Difference between revisions of "Team:IIT-Madras"

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<h5> Editing your wiki </h5>
 
<h5> Editing your wiki </h5>
 
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
 
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> Click here to edit this page! </a></p>
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<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> </a>Use WikiTools - Edit in the black menu bar to edit this page</p>
  
 
</div>
 
</div>
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<h5> Pictures and files </h5>
 
<h5> Pictures and files </h5>
 
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
 
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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When you upload, set the "Destination Filename" to <br><code>T--YourOfficialTeamName--NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
  
  
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<div class="column full_size" >
 
<div class="column full_size" >
<p>When we started to ideate for iGEM 2016, our goals were to tackle two of the fundamental issues being faced in  synthetic biology today -  estimating modularity of RBSs and predicting the variations in the protein expression levels and designing an efficient measurement device. Our final project will consist of 3 modules - RIBOS riboregulatory switches, efficient measurement device, and characterizing widely used RBSs for their modularity.</p>
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<p>When we started to ideate for iGEM 2016, our goals were to tackle two of the fundamental issues being faced in  synthetic biology today -  estimating modularity of RBSs and predicting the variations in the protein expression levels and designing an efficient measurement device. We have also designed efficient ribo switches and been using them for several potential applications e.g. inhibition of HGT etc. Our final project will consist of 3 modules - RIBOS riboregulatory switches, efficient measurement device, and characterizing widely used RBSs for their modularity.</p>
 
<br></br>
 
<br></br>
<p>RIBOS(RNA Inducible Boolean like Output Switches) is a regulatory system in which presence or absence of mRNA molecules of one gene can modulate the expression of other genes.RIBOS devices are triggered by RNA sequences and give output in the form of activation or repression of translation of specific RNA sequences. We have designed RIBOS for scalability, modularity, orthogonality and composability. We wish to characterize RIBOS for tunability and highly precise outputs. It can be game changing in the field of synthetic biology, it's applications range from detection and quantification of mRNA molecules to the design of extensive independent and modular genetic circuits using forward engineering.</p>
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<p>RIBOS(RNA Inducible Boolean like Output Switches) is a regulatory system in which presence or absence of mRNA molecules of one gene can modulate the expression of other genes. RIBOS devices are triggered by RNA sequences and give output in the form of activation or repression of translation of specific RNA sequences. We have designed RIBOS for scalability, modularity, orthogonality and composability. We wish to characterize RIBOS for tunability and highly precise outputs. It can be game changing in the field of synthetic biology, it's applications range from detection and quantification of mRNA molecules to the design of extensive independent and modular genetic circuits using forward engineering.</p>
  
  

Revision as of 09:07, 5 July 2016

Welcome to IIT Madras's wiki for iGEM 2016!

When we started to ideate for iGEM 2016, our goals were to tackle two of the fundamental issues being faced in synthetic biology today - estimating modularity of RBSs and predicting the variations in the protein expression levels and designing an efficient measurement device. We have also designed efficient ribo switches and been using them for several potential applications e.g. inhibition of HGT etc. Our final project will consist of 3 modules - RIBOS riboregulatory switches, efficient measurement device, and characterizing widely used RBSs for their modularity.



RIBOS(RNA Inducible Boolean like Output Switches) is a regulatory system in which presence or absence of mRNA molecules of one gene can modulate the expression of other genes. RIBOS devices are triggered by RNA sequences and give output in the form of activation or repression of translation of specific RNA sequences. We have designed RIBOS for scalability, modularity, orthogonality and composability. We wish to characterize RIBOS for tunability and highly precise outputs. It can be game changing in the field of synthetic biology, it's applications range from detection and quantification of mRNA molecules to the design of extensive independent and modular genetic circuits using forward engineering.