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Kill Switch Database
We already started to investigate the mechanisms behind different kill switch classes. Building on that we created a database for the whole scientific community to improve the search for reliable and stable kill switch designs. Together with the tool developed in our modeling section, we provide a great framework to improve safety of projects in Synthetic Biology.
The database includes all kill switches ever implemented in iGEM since 2004 delivering a pictured topology, part numbers, kill switch classes and links to the wiki on which the system was described. Figures 1 to 4 show navigation through the database.
This intuitively usable tool will help teams all around the world to implement these essential safety mechanisms in their projects in Synthetic Biology and biotechnological applications. Find the kill switch database here: