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<img src="https://static.igem.org/mediawiki/2016/d/d2/T--HokkaidoU_Japan--project_description.png" | <img src="https://static.igem.org/mediawiki/2016/d/d2/T--HokkaidoU_Japan--project_description.png" | ||
− | width="300px" height=" | + | width="300px" height="110px" alt="Project description"> |
− | < | + | <p><font face="Avenir"font color="#333"font size="5">H<font size="4">ydrogel is used in contact lenses and diapers. |
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Some kinds of hydrogel are made of self-assembling peptides. | Some kinds of hydrogel are made of self-assembling peptides. | ||
They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. | They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. | ||
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They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. | They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. | ||
So, we need another approach including biosynthesis.</p> | So, we need another approach including biosynthesis.</p> | ||
− | <p><font size="5">I<font size="4">n this research, we expressed self-assembling peptides such as | + | <p><font face="Avenir" font size="5">I<font face="Avenir" font size="4">n this research, we expressed self-assembling peptides such as |
− | <br><font | + | <br><font face="Avenir" font size="5"><CENTER>RADA-16 I<font face="Avenir" font size="4"> |
− | and <font face=" | + | and <font face="Avenir" font size="5">P<sub>11</sub>-4<font face="Avenir" font size="4"></CENTER> |
in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/> | in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/> | ||
− | <p><font size="5">W<font size="4">e also considered the application of hydrogel to immobilized proteins, | + | <p><font face="Avenir" font size="5">W<font face="Avenir" font size="4">e also considered the application of hydrogel to immobilized proteins, |
which may enhance the stability of proteins. | which may enhance the stability of proteins. | ||
Immobilized proteins will be used in medicine and environmental study in the future.</font></p> | Immobilized proteins will be used in medicine and environmental study in the future.</font></p> | ||
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</html> | </html> |
Latest revision as of 07:12, 30 August 2016
Team:HokkaidoU Japan
Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. So, we need another approach including biosynthesis.
In this research, we expressed self-assembling peptides such as
We also considered the application of hydrogel to immobilized proteins, which may enhance the stability of proteins. Immobilized proteins will be used in medicine and environmental study in the future.