Difference between revisions of "Team:HokkaidoU Japan"
| Line 1: | Line 1: | ||
{{HokkaidoU_Japan}} | {{HokkaidoU_Japan}} | ||
<html> | <html> | ||
| − | + | Project description | |
<p>Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amount. So, we need another approach including biosynthesis.</p> | <p>Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amount. So, we need another approach including biosynthesis.</p> | ||
<p>In this research, we expressed self-assembling peptides such as RADA-16 I and P<sub>11</sub>-4 in Escherichia coli and analyzed them by series of experiments. <p/> | <p>In this research, we expressed self-assembling peptides such as RADA-16 I and P<sub>11</sub>-4 in Escherichia coli and analyzed them by series of experiments. <p/> | ||
Revision as of 13:25, 3 July 2016
"
Team:HokkaidoU Japan
Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amount. So, we need another approach including biosynthesis.
In this research, we expressed self-assembling peptides such as RADA-16 I and P11-4 in Escherichia coli and analyzed them by series of experiments.
We also considered application of hydrogel to immobilized proteins, which may enhance the stability of proteins. Immobilized proteins will be used in medicine and environmental study in the future.
