Team:TAS Taipei/Software

Software - TAS Taipei iGEM Wiki





Software

Generalized Nanoparticle Customizer

We built a nanoparticle customizer, which allows you to track the concentration and rates of drug delivery to any part of the body using nanoparticles. You can customize your own design of nanoparticles, and analyze its function inside the body.

These software tools are based off our model results. The specific equations used in this calculator can be found, in the collapsible details in the Model page.

This computational software can be used by future iGEM teams who are interested in using nanoparticles to efficiently deliver their synthesized proteins. The calculational tool is programmed on a Google Spreadsheet. Click the button below to visit the spreadsheet. Please make a copy of the spreadsheet to freely use it.

Cataract - Specific Calculator Tool

We also built two calculators, one for prevention, one for treatment, that is specific to our project.

CALCULATOR

Prevention

LOCS Score Threshold:
We guarentee that by applying this prevention eyedrop daily, your LOCS score will remain below your threshold for 50 years.


Prevention Results
Variable Value Source
Allowable LOCS    
Crystallin Damage       c.d. Model 1
GSR Maintained      uM Model 2
Nanoparticle Conc.      uM Model 3
Eyedrop Conc.      mM Model 4
Eyedrop Result      mg/mL

Treatment

Your current LOCS Score:
By applying the following treatment, leaving an hour before each dose of eyedrops, we guarentee that it will lower your LOCS score to essentially 0.


Treatment Results
Variable Value Source
Allowable LOCS    
Crystallin Damage       c.d. Model 2
Absorbance      a.u. Model 1
CH25H      uM Model 5
Eyedrop Conc.      uM Model 4
Eyedrop Result      mg/mL Model 4
# of Eyedrops      drops (of 0.8 mg/mL eyedrop)



Prevention

GSR Eyedrop

Treatment

25HC Eyedrop

LOCS: 0      


Eyedrops




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