Difference between revisions of "Team:HokkaidoU Japan/Overview"
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<div id="Project_Description"><img src="https://static.igem.org/mediawiki/2016/d/d2/T--HokkaidoU_Japan--project_description.png" | <div id="Project_Description"><img src="https://static.igem.org/mediawiki/2016/d/d2/T--HokkaidoU_Japan--project_description.png" | ||
width="300px" height="110px" alt="Project description"></div> | width="300px" height="110px" alt="Project description"></div> | ||
| − | <p> | + | <p>Hydrogel is used in contact lenses and diapers. |
Some kinds of hydrogel are made of self-assembling peptides. | Some kinds of hydrogel are made of self-assembling peptides. | ||
They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. | They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. | ||
| Line 12: | Line 12: | ||
They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. | They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. | ||
So, we need another approach including biosynthesis.</p> | So, we need another approach including biosynthesis.</p> | ||
| − | <p> | + | <p>In this research, we expressed self-assembling peptides such as |
| − | <br | + | <br><CENTER>RADA-16 I |
| − | and | + | and P11-4</CENTER> |
in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/> | in <i>Escherichia coli</i> and analyzed them by a series of experiments. <p/> | ||
| − | <p> | + | <p>We also considered the application of hydrogel to immobilized proteins, |
which may enhance the stability of proteins. | which may enhance the stability of proteins. | ||
Immobilized proteins will be used in medicine and environmental study in the future.</font></p> | Immobilized proteins will be used in medicine and environmental study in the future.</font></p> | ||
Revision as of 17:47, 1 October 2016
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Team:HokkaidoU Japan
Hydrogel is used in contact lenses and diapers. Some kinds of hydrogel are made of self-assembling peptides. They are amphiphilic peptides and they form nanostructured hydrogel under physiochemical conditions. Recently, they have been considered as a good biological scaffold for cell culturing and drug delivering. They are synthesized chemically such as solid-state synthesis, but it’s not efficient for production in large amounts. So, we need another approach including biosynthesis.
In this research, we expressed self-assembling peptides such as
We also considered the application of hydrogel to immobilized proteins, which may enhance the stability of proteins. Immobilized proteins will be used in medicine and environmental study in the future.
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