Difference between revisions of "Team:Tel-Hai"
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<div class="flipper"><div class="front"> | <div class="flipper"><div class="front"> | ||
| − | <h3><span>Where<span> is the magic happening?</h3> | + | <h3><span>Where</span> is the magic happening?</h3> |
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<p>Tel-Hai and MIGAL's labs located in northen Israel</h3> | <p>Tel-Hai and MIGAL's labs located in northen Israel</h3> | ||
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<div class="flipper"><div class="front"> | <div class="flipper"><div class="front"> | ||
| − | <h3><span>Who<span> are we?</h3> | + | <h3><span>Who</span> are we?</h3> |
</div><div class="back"> | </div><div class="back"> | ||
<p>Group of dedicated students and researchers from the fields of biotechnology and biochemistry</p> | <p>Group of dedicated students and researchers from the fields of biotechnology and biochemistry</p> | ||
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<div class="flipper"><div class="front"> | <div class="flipper"><div class="front"> | ||
| − | <h3><span>What<span> is our goal?</h3> | + | <h3><span>What</span> is our goal?</h3> |
</div><div class="back"> | </div><div class="back"> | ||
<p>Correcting the most prevalent mutation in the CFTR protein, causing Cystic Fibrosis, in somatic cells</p> | <p>Correcting the most prevalent mutation in the CFTR protein, causing Cystic Fibrosis, in somatic cells</p> | ||
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<div class="flipper"><div class="front"> | <div class="flipper"><div class="front"> | ||
| − | <h3><span>Why<span> choose this?</h3> | + | <h3><span>Why</span> choose this?</h3> |
</div><div class="back"> | </div><div class="back"> | ||
<p>This is a "simple" missense mutation, leading the to loss of single amino acid, causing Cystic Fibrosis - a largely researched lethal genetic disease, found in every ethnic group world-wide.</p> | <p>This is a "simple" missense mutation, leading the to loss of single amino acid, causing Cystic Fibrosis - a largely researched lethal genetic disease, found in every ethnic group world-wide.</p> | ||
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<div class="flipper"><div class="front"> | <div class="flipper"><div class="front"> | ||
| − | <h3><span>Why now<span> of all times?</h3> | + | <h3><span>Why now</span> of all times?</h3> |
</div><div class="back"> | </div><div class="back"> | ||
<p>Only recently has genome editing become an affordable and practical tool for <strong>all researchers</strong>, to maximize efficiency in correcting diseases causing mutations.</p> | <p>Only recently has genome editing become an affordable and practical tool for <strong>all researchers</strong>, to maximize efficiency in correcting diseases causing mutations.</p> | ||
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| − | <h3><span>How<span>?</h3> | + | <h3><span>How</span>?</h3> |
</div><div class="back"> | </div><div class="back"> | ||
<p>Utilizing the Cholera toxin's non-toxic B Sub-unit as a delivery system for a plasmid containing a CRISPR/Cas9 apparatus, so as to specifically correct the defected DNA fragment with minimal collateral damage.</p> | <p>Utilizing the Cholera toxin's non-toxic B Sub-unit as a delivery system for a plasmid containing a CRISPR/Cas9 apparatus, so as to specifically correct the defected DNA fragment with minimal collateral damage.</p> | ||
Revision as of 09:47, 13 October 2016
iGEM Tel-Hai 2016
Where is the magic happening?
Tel-Hai and MIGAL's labs located in northen Israel
Who are we?
Group of dedicated students and researchers from the fields of biotechnology and biochemistry
What is our goal?
Correcting the most prevalent mutation in the CFTR protein, causing Cystic Fibrosis, in somatic cells
Why choose this?
This is a "simple" missense mutation, leading the to loss of single amino acid, causing Cystic Fibrosis - a largely researched lethal genetic disease, found in every ethnic group world-wide.
Why now of all times?
Only recently has genome editing become an affordable and practical tool for all researchers, to maximize efficiency in correcting diseases causing mutations.
How?
Utilizing the Cholera toxin's non-toxic B Sub-unit as a delivery system for a plasmid containing a CRISPR/Cas9 apparatus, so as to specifically correct the defected DNA fragment with minimal collateral damage.
