Entrepreneurship - TAS Taipei iGEM Wiki

PROJECT

Background

Achievements

Collaborations

Parts

Cataracts - the leading cause of blindness. Find out how we can non-invasively treat and prevent cataract formation.
EXPERIMENTAL

Lens Cataract Model

Prevention and Treatment Constructs

Delivery Prototype

Notebook

We build constructs to make our great ideas become reality. Follow along our discovery of exciting science!
MODEL

GSR Function

Prototype Delivery

CH25H Treatment

Calculator

Computational Biology provides us models that we cannot easily test experimentally. Click to find out the results of our modeling, and the math behind it!
HUMAN PRACTICE

Research

Outreach

Impact

We don't just grow cool bacteria. We make a difference. Find out how we tackled social aspects of this project.
SAFETY

Overview

Biosafety

Risk Reduction Methods

Further Questions

Safety first. Especially in a lab. Here's how we maintained and investigated the integrity and security of our work environment.
TEAM

Members

About

Attributions

Wiki Standard Pages

Every iGEM project is the accumulation of an entire year's hard work by a group of cheerful students. Meet the team!

C◎UNTERACTS

Attributions

All lab work was conducted at Taipei American School Sandy R. Puckett Memorial Research Laboratory by team members of the 2016 TAS-Taipei iGEM team, unless stated otherwise

National Yang Ming University - NYMU_Taipei team (click to see collaboration page)
- Consultation for troubleshooting our cloning procedure
- Ran summer camp to overview entire iGEm process from start to finish
- Ran nanoparticle calculator to give advice and troubleshoot problems and misunderstandings
ASIJ - ASIJ_Tokyo team
- Testing our cataract treatment and prevention calculator and providing user feedback
Dr. Jason Cyster - Professor at UCSF University Department of Microbiology and Immunology
- Advice on working with 25HC and exploring its properties in terms of cataracts treatment
Dr. Tsu Chieh Cheng - Optomologist at Chang Cheng Eye Hospital
- Information on challenges with current drug delivery systems and cataracts surgery
- Feedback on our prototype plan
Dr. Wei-Chu Wu - Retina Specialist, Associate Professor at Chang Gung Memorial Hospital
- Information on current cataracts treatments and post operational complications
Dr. Li Guo Min - Veterinarian at Nicholas Animal Hospital
- Information on cataract development in animals and current treatments, such as the Ocluvet eye drops
Dr. Jason Gestwicki - Professor at UCSF School of Medicine
- Advice on 25HC regarding protein aggression and molecular interaction
Dr. Eric (Ricky) P. Lee - Senior member of Technical Staff at Maxim Integrated
- Assistance with troubleshooting problems encountered during nanoparticle synthesis and protein encapsulation
Mrs. Michelle Bruce - Economics Teacher at Taipei American School
- Reviewing and providing feedback on our business plan
Mr. Alexander kaufman - Former intern at RA Capital
- Feedback on our business plan
Dr. Catriona Moran and Mrs. Sharon Clapper
- Sharing their experiences as cataracts patients and feedback on our final product
Mission Biotech
- Internal cutting sites removal for GSR and CH25H
Integrated DNA Technologies
- CH25H gene fragment, CRYAB gene fragment, GFP full construct, CH25H full construct
Tri-I biotech
- Sequencing and primers synthesis
- Primer synthesis to remove stop codon (every gene we ordered)
- Origene
- cDNA for CRYAA and GSR

People involved in our bioethics panel
- Mr. Steve Anderson
- Ms. Anisha Vinod
- Dr. Nathaniel Smith
- Dr. Evonne Vidal
- Mr. Brandon Maguire
- Dr. Annemarie Costello

Some parts of this wiki have been derived from the 2014 and 2015 TAS_Taipei wiki, which was designed entirely by the 2014 and 2015 teams. All other components were designed by students of the 2016 team.