Team:BIT/Game
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GAME
Introduction
The purpose of synthetic biology is to create artificial biological systems. We connect a certain amount of gene to build gene network, making them run like a circuit. According to this principle, the game players play an engineering bacterium and look for gene fragments in each level of adventure, to form a complete genetic line, so that the engineering bacteria can be changed to special bacteria that are used to solve disease or environmental problems.
The operation of this game is simple and flexible. The left key controls the role move towards left and the right key controls it move towards right. In this game, player tries to find possible solutions about the disease and environmental problems which human beings pay close attention to. The game involves the knowledge of synthetic biology, including gene lines, transformation of engineering bacteria, disease monitoring and so on, which can introduce synthetic biology to a certain amount of teenagers, and deepen their understanding of the ways to solve disease and environmental problems.
The goal of making this game is embedding science into game, to expand the accepting crowd of scientific knowledge. This game is a 2D horizontal board scroll category casual games. Each level of the game contains the method of a specific disease environmental problem, and different levels have different story backgrounds and ways of playing, which make the game become more interesting to play.
Design
Dr. Lee has troubles when he solve environmental and disease problems by transforming engineering bacteria. So he decides to ask his students Keith to use VR technology to simulate the visual angle of Escherichia coli, looking for the genetic fragments to build the right genetic route, changing the engineering bacteria to special bacteria which can solve environmental and disease problems. Dr. Lee will give instructions to Keith while he looking for genetic fragments.
Postgraduate
Dr. Lee (NPC): Our research has encountered difficulties, so I need to investigate which step has problem in the genetic line. The whole device related on simulation system based VR that it gives prominence to the operation of the user. By which I need you to play the role of Escherichia coli to discover correct gene line, and I will give you instructions in the process.
Keith(Player): Cope that.
The first level: The treatment of UITS
Principle of the level: Treating UITS according to the solution to the antibiotic resistance.
Level feature: The level is for teaching novice. Players keep walking forward and follow the instructions to collect five genetic fragments, and then reach the terminal point to finish this level. Players play engineering bacterias to find the right genetic lines, to transform it into a special strain which can detect USTC. The scene of the level is suburb during the daytime.
The second level: detecting tuberculosis.
Principle of the level: Using the genetic lines to transform the Escherichia coli which infected by λ phage into the engineering bacteria which can detect tuberculosis.
When λ phage infects the Escherichia coli, Cro starts expressing and inhibiting the expression of CI, Leading the E. coli to lysis and release λ phage.
Level feature: There is new chase system added in this level. Player not only needs to collect genetic fragments, but also must catch the λ phage which can move freely. The scene of the level is suburb at night.
The third level: detecting aromatics and caffeine.
Principle of the level: Toxicity and persistence of aromatic pollutants in the environment can cause great harm to the human body. Building aromatic compounds sensor according to the genetic route can detect 44 different kinds of aromatic compounds. TF can activate the degradation of line as a transcription factor.
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Contact Us
Beijing Institute of Technology,
No. 5 South Zhong Guan Cun Street,
Haidian Beijing 100081, P. R. China
Twitter : @igem_BIT
Sina Weibo : @igem_BIT
Website : http://www.bit.edu.cn
