Difference between revisions of "Team:Bordeaux"

Line 1: Line 1:
 
{{Bordeaux}}
 
{{Bordeaux}}
−
<html>
+
<html lang="en">
  
−
<div class="column full_size" >
+
<head>
−
<img src="http://placehold.it/800x300/d3d3d3/f2f2f2">
+
−
</div>
+
  
−
<div class="column full_size" >
+
    <meta charset="utf-8">
−
<h2> Welcome to iGEM 2016! </h2>
+
    <meta http-equiv="X-UA-Compatible" content="IE=edge">
−
<p>Your team has been approved and you are ready to start the iGEM season! </p>
+
    <meta name="viewport" content="width=device-width, initial-scale=1">
 +
    <meta name="description" content="Homepage of iGEM Bordeaux 2016">
 +
    <meta name="author" content="Team Wiki (Savandara BESSE & Jérémy LE COZ)">
  
−
</div>  
+
    <title>Homepage</title>
  
−
<div class="column half_size" >
+
    <!-- Bootstrap Core CSS à ajouter dans un template -->
−
<h5>Before you start: </h5>
+
    <link href="css/bootstrap.min.css" rel="stylesheet">
−
<p> Please read the following pages:</p>
+
−
<ul>
+
−
<li>  <a href="https://2016.igem.org/Requirements">Requirements page </a> </li>
+
−
<li> <a href="https://2016.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
+
−
<li> <a href="https://2016.igem.org/Resources/Template_Documentation"> Template Documentation </a></li>
+
−
</ul>
+
−
</div>
+
  
−
<div class="column half_size" >
+
    <!-- Custom CSS à ajouter dans un template -->
−
<div class="highlight">
+
    <style>
−
<h5> Styling your wiki </h5>
+
−
<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
+
−
<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
+
−
</div>
+
−
</div>
+
  
−
<div class="column full_size" >
+
/*
−
<h5> Wiki template information </h5>
+
* Start Bootstrap - Grayscale Bootstrap Theme (http://startbootstrap.com)
−
<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
+
* Code licensed under the Apache License v2.0.
 +
* For details, see http://www.apache.org/licenses/LICENSE-2.0.
 +
*/
  
−
</div>
+
/*Global part*/
  
 +
body {
 +
    width: 100%;
 +
    height: 100%;
 +
    font-family: Raleway,"Helvetica Neue",Helvetica,Arial,sans-serif;
 +
    color: #000;
 +
    background-color: #d4dce4;
 +
}
  
 +
html {
 +
    width: 100%;
 +
    height: 100%;
 +
}
  
 +
h1,
 +
h2,
 +
h3,
 +
h4,
 +
h5,
 +
h6 {
 +
    margin: 0 0 35px;
 +
    text-transform: uppercase;
 +
    font-family: Montserrat, cursive,"Helvetica Neue",Helvetica,Arial,sans-serif;
 +
    font-weight: 700;
 +
    letter-spacing: 1px;
 +
}
  
−
<div class="column half_size" >
+
p {
−
<h5> Editing your wiki </h5>
+
    margin: 0 0 25px;
−
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
+
    font-size: 18px;
−
<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> Click here to edit this page! </a></p>
+
    line-height: 1.5;
 +
}
  
−
</div>
+
@media(min-width:768px) {
 +
    p {
 +
        margin: 0 0 35px;
 +
        font-size: 20px;
 +
        line-height: 1.6;
 +
    }
 +
}
  
 +
a {
 +
    color: #42dca3;
 +
    -webkit-transition: all .2s ease-in-out;
 +
    -moz-transition: all .2s ease-in-out;
 +
    transition: all .2s ease-in-out;
 +
}
  
−
<div class="column half_size" >
+
a:hover,
−
<h5>Tips</h5>
+
a:focus {
−
<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
+
    text-decoration: none;
−
<ul>
+
    color: #1d9b6c;
−
<li>State your accomplishments! Tell people what you have achieved from the start. </li>
+
}
−
<li>Be clear about what you are doing and how you plan to do this.</li>
+
−
<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
+
−
<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
+
−
<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
+
−
<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
+
−
<li>Have lots of fun! </li>
+
−
</ul>
+
−
</div>
+
  
 +
.light {
 +
    font-weight: 400;
 +
}
  
−
<div class="column half_size" >
+
.navbar-custom {
−
<h5>Inspiration</h5>
+
    margin-bottom: 0;
−
<p> You can also view other team wikis for inspiration! Here are some examples:</p>
+
    border-bottom: 1px solid rgba(255,255,255,.3);
−
<ul>
+
    text-transform: uppercase;
−
<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
+
    font-family: Montserrat, cursive,"Helvetica Neue",Helvetica,Arial,sans-serif;
−
<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
+
    background-color: #;
−
<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
+
}
−
<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
+
−
<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
+
−
<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
+
−
</ul>
+
−
</div>
+
  
−
<div class="column half_size" >
+
.navbar-custom .navbar-brand {
−
<h5> Uploading pictures and files </h5>
+
    font-weight: 700;
−
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
+
}
−
When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
+
  
 +
.navbar-custom .navbar-brand:focus {
 +
    outline: 0;
 +
}
  
−
<div class="button_click"  onClick=" parent.location= 'https://2016.igem.org/Special:Upload '"> 
+
.navbar-custom .navbar-brand .navbar-toggle {
−
UPLOAD FILES
+
    padding: 4px 6px;
−
</div>
+
    font-size: 16px;
 +
    color: #fff;
 +
}
  
−
</div>
+
.navbar-custom .navbar-brand .navbar-toggle:focus,
 +
.navbar-custom .navbar-brand .navbar-toggle:active {
 +
    outline: 0;
 +
}
  
 +
.navbar-custom a {
 +
    color: #fff;
 +
}
  
 +
.navbar-custom .nav li a {
 +
    -webkit-transition: background .3s ease-in-out;
 +
    -moz-transition: background .3s ease-in-out;
 +
    transition: background .3s ease-in-out;
 +
}
  
 +
.navbar-custom .nav li a:hover {
 +
    outline: 0;
 +
    color: rgba(255,255,255,.8);
 +
    background-color: transparent;
 +
}
  
 +
.navbar-custom .nav li a:focus,
 +
.navbar-custom .nav li a:active {
 +
    outline: 0;
 +
    background-color: transparent;
 +
}
  
 +
.navbar-custom .nav li.active {
 +
    outline: 0;
 +
}
  
 +
.navbar-custom .nav li.active a {
 +
    background-color: rgba(255,255,255,.3);
 +
}
 +
 +
.navbar-custom .nav li.active a:hover {
 +
    color: #fff;
 +
}
 +
 +
.dropdown:hover .dropdown-menu{
 +
  display: block;
 +
  padding: 3px 20px;
 +
  clear: both;
 +
  font-weight: normal;
 +
  line-height: 1.42857143;
 +
  white-space: nowrap;
 +
}
 +
 +
.dropdown-menu li:hover {
 +
  background: #337ab7;
 +
}
 +
 +
@media(min-width:768px) {
 +
    .navbar-custom {
 +
        padding: 20px 0;
 +
        border-bottom: 0;
 +
        letter-spacing: 1px;
 +
        background: 0 0;
 +
        -webkit-transition: background .5s ease-in-out,padding .5s ease-in-out;
 +
        -moz-transition: background .5s ease-in-out,padding .5s ease-in-out;
 +
        transition: background .5s ease-in-out,padding .5s ease-in-out;
 +
    }
 +
 +
    .navbar-custom.top-nav-collapse {
 +
        padding: 0;
 +
        border-bottom: 1px solid rgba(255,255,255,.3);
 +
        background: #000;
 +
    }
 +
}
 +
 +
.intro {
 +
    display: table;
 +
    width: 100%;
 +
    height: auto;
 +
    padding: 100px 0;
 +
    text-align: center;
 +
    color: white;
 +
    text-shadow: #000000 1px 1px, #000000 -1px 1px, #000000 -1px -1px, #000000 1px -1px;
 +
    /*background: url(../img/Bdx_by_Marie.jpg) no-repeat bottom center scroll;*/
 +
    background: url(../img/worms.gif) no-repeat bottom center scroll;
 +
    background-color: #000;
 +
    -webkit-background-size: cover;
 +
    -moz-background-size: cover;
 +
    background-size: cover;
 +
    -o-background-size: cover;
 +
}
 +
 +
.intro .intro-body {
 +
    display: table-cell;
 +
    vertical-align: middle;
 +
}
 +
 +
.intro .intro-body .brand-heading {
 +
    font-size: 40px;
 +
}
 +
 +
.intro .intro-body .intro-text {
 +
    font-size: 18px;
 +
}
 +
 +
.intro-team {
 +
    display: table;
 +
    width: 100%;
 +
    height: auto;
 +
    padding: 100px 0;
 +
    text-align: center;
 +
    text-shadow: #000000 1px 1px, #000000 -1px 1px, #000000 -1px -1px, #000000 1px -1px;
 +
    color: #fff;
 +
    background: url(../img/downloads-bg.jpg) no-repeat bottom center scroll;
 +
    background-color: #000;
 +
    -webkit-background-size: cover;
 +
    -moz-background-size: cover;
 +
    background-size: cover;
 +
    -o-background-size: cover;
 +
}
 +
 +
#sponsors {
 +
    display: table;
 +
    width: 100%;
 +
    height: auto;
 +
    padding: 100px 0;
 +
    text-align: center;
 +
    color: black;
 +
    background-color: white;
 +
    -webkit-background-size: cover;
 +
    -moz-background-size: cover;
 +
    background-size: cover;
 +
    -o-background-size: cover;
 +
 +
}
 +
 +
 +
@media(min-width:768px) {
 +
    .intro {
 +
        height: 100%;
 +
        padding: 0;
 +
    }
 +
 +
    .intro .intro-body .brand-heading {
 +
        font-size: 100px;
 +
    }
 +
 +
    .intro .intro-body .intro-text {
 +
        font-size: 26px;
 +
    }
 +
}
 +
 +
.btn-circle {
 +
    width: 70px;
 +
    height: 70px;
 +
    margin-top: 15px;
 +
    padding: 7px 16px;
 +
    border: 2px solid #fff;
 +
    border-radius: 100%!important;
 +
    font-size: 40px;
 +
    color: #fff;
 +
    background: 0 0;
 +
    -webkit-transition: background .3s ease-in-out;
 +
    -moz-transition: background .3s ease-in-out;
 +
    transition: background .3s ease-in-out;
 +
}
 +
 +
.btn-circle:hover,
 +
.btn-circle:focus {
 +
    outline: 0;
 +
    color: #fff;
 +
    background: rgba(255,255,255,.1);
 +
}
 +
 +
.btn-circle i.animated {
 +
    -webkit-transition-property: -webkit-transform;
 +
    -webkit-transition-duration: 1s;
 +
    -moz-transition-property: -moz-transform;
 +
    -moz-transition-duration: 1s;
 +
}
 +
 +
.btn-circle:hover i.animated {
 +
    -webkit-animation-name: pulse;
 +
    -moz-animation-name: pulse;
 +
    -webkit-animation-duration: 1.5s;
 +
    -moz-animation-duration: 1.5s;
 +
    -webkit-animation-iteration-count: infinite;
 +
    -moz-animation-iteration-count: infinite;
 +
    -webkit-animation-timing-function: linear;
 +
    -moz-animation-timing-function: linear;
 +
}
 +
 +
@-webkit-keyframes pulse {   
 +
    0% {
 +
        -webkit-transform: scale(1);
 +
        transform: scale(1);
 +
    }
 +
 +
    50% {
 +
        -webkit-transform: scale(1.2);
 +
        transform: scale(1.2);
 +
    }
 +
 +
    100% {
 +
        -webkit-transform: scale(1);
 +
        transform: scale(1);
 +
    }
 +
}
 +
 +
@-moz-keyframes pulse {   
 +
    0% {
 +
        -moz-transform: scale(1);
 +
        transform: scale(1);
 +
    }
 +
 +
    50% {
 +
        -moz-transform: scale(1.2);
 +
        transform: scale(1.2);
 +
    }
 +
 +
    100% {
 +
        -moz-transform: scale(1);
 +
        transform: scale(1);
 +
    }
 +
}
 +
 +
.content-section {
 +
    padding-top: 100px;
 +
}
 +
 +
.team-section {
 +
    width: 100%;
 +
    padding: 50px 0;
 +
    color: #fff;
 +
    background: url(../img/downloads-bg.jpg) no-repeat center center scroll;
 +
    background-color: #000;
 +
    -webkit-background-size: cover;
 +
    -moz-background-size: cover;
 +
    background-size: cover;
 +
    -o-background-size: cover;
 +
}
 +
 +
 +
@media(min-width:767px) {
 +
    .content-section {
 +
        padding-top: 250px;
 +
    }
 +
 +
    .team-section {
 +
        padding: 100px 0;
 +
    }
 +
 +
    #map {
 +
        height: 400px;
 +
        margin-top: 250px;
 +
    }
 +
}
 +
 +
.btn {
 +
    border-radius: 0;
 +
    text-transform: uppercase;
 +
    font-family: Montserrat,"Helvetica Neue",Helvetica,Arial,sans-serif;
 +
    font-weight: 400;
 +
    -webkit-transition: all .3s ease-in-out;
 +
    -moz-transition: all .3s ease-in-out;
 +
    transition: all .3s ease-in-out;
 +
}
 +
 +
.btn-default {
 +
    border: 1px solid #42dca3;
 +
    color: #42dca3;
 +
    background-color: transparent;
 +
}
 +
 +
.btn-default:hover,
 +
.btn-default:focus {
 +
    border: 1px solid #42dca3;
 +
    outline: 0;
 +
    color: #000;
 +
    background-color: #42dca3;
 +
}
 +
 +
ul.banner-social-buttons {
 +
    margin-top: 0;
 +
}
 +
 +
@media(max-width:1199px) {
 +
    ul.banner-social-buttons {
 +
        margin-top: 15px;
 +
    }
 +
}
 +
 +
@media(max-width:767px) {
 +
    ul.banner-social-buttons li {
 +
        display: block;
 +
        margin-bottom: 20px;
 +
        padding: 0;
 +
    }
 +
 +
    ul.banner-social-buttons li:last-child {
 +
        margin-bottom: 0;
 +
    }
 +
}
 +
 +
footer {
 +
    padding: 50px 0;
 +
}
 +
 +
footer p {
 +
    margin: 0;
 +
}
 +
 +
::-moz-selection {
 +
    text-shadow: none;
 +
    background: #fcfcfc;
 +
    background: rgba(255,255,255,.2);
 +
}
 +
 +
::selection {
 +
    text-shadow: none;
 +
    background: #fcfcfc;
 +
    background: rgba(255,255,255,.2);
 +
}
 +
 +
img::selection {
 +
    background: 0 0;
 +
}
 +
 +
img::-moz-selection {
 +
    background: 0 0;
 +
}
 +
 +
body {
 +
    webkit-tap-highlight-color: rgba(255,255,255,.2);
 +
}
 +
 +
/*Team part*/
 +
 +
.banner_team {
 +
padding : 250px 250px 350px 250px;
 +
background: url(../img/Team/Team.jpg) /*no-repeat center center fixed*/;
 +
    -webkit-background-size: cover;
 +
    -moz-background-size: cover;
 +
    -o-background-size: cover;
 +
    background-size: cover;
 +
}
 +
 +
.roundedImage {
 +
    display:inline-table;
 +
    overflow:hidden;
 +
    border-collapse: separate;
 +
    -webkit-border-radius:50px;
 +
    -moz-border-radius:50px;
 +
    border-radius:10px;
 +
    width:150px;
 +
    height:150px;
 +
}
 +
 +
li.roundedImage {
 +
    font-size : 1em;
 +
}
 +
 +
</style>
 +
    <!-- Custom Fonts -->
 +
    <link href="font-awesome/css/font-awesome.min.css" rel="stylesheet" type="text/css">
 +
    <link href="http://fonts.googleapis.com/css?family=Montserrat:400,700,400italic,700italic" rel="stylesheet" type="text/css">
 +
    <link href="http://fonts.googleapis.com/css?family=Raleway:400,700,400italic,700italic" rel="stylesheet" type="text/css">
 +
   
 +
    <script type="text/javascript" src="jquery-1.12.3.min.js"></script>
 +
    <script type="text/javascript" src="alphabet.js"></script>
 +
 +
    <!-- HTML5 Shim and Respond.js IE8 support of HTML5 elements and media queries -->
 +
    <!-- WARNING: Respond.js doesn't work if you view the page via file:// -->
 +
    <!--[if lt IE 9]>
 +
        <script src="https://oss.maxcdn.com/libs/html5shiv/3.7.0/html5shiv.js"></script>
 +
        <script src="https://oss.maxcdn.com/libs/respond.js/1.4.2/respond.min.js"></script>
 +
    <![endif]-->
 +
 +
</head>
 +
 +
<body id="page-top" data-spy="scroll" data-target=".navbar-fixed-top">
 +
 +
<!--Navigation-->
 +
<div id="menu">
 +
{{Team:Bordeaux/menu}}
 +
</div>
 +
 +
    <!-- Header -->
 +
    <header class="intro">
 +
        <div class="intro-body">
 +
            <div class="container">
 +
                <div class="row">
 +
                    <div class="col-md-8 col-md-offset-2">
 +
                        <! -- <img src ="./img/iGEM_Bordeaux_logo_v2.png" width=75% height=75% title="iGEM Bordeaux 2016"> -->
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<p class="intro-text" style=" font-size: 3.5em"><b>Sleep with EpiC <I>Elegans</I></p>
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                <h2>Abstract</h2>
 +
 +
    <!--
 +
    French version
 +
  Qui n’a jamais souffert de troubles de sommeil ?
 +
 +
  D'après un rapport de l'INPES de 2008, 45% des 25-45 ans interrogés estiment ne pas dormir suffisament. Ce manque génère un nombre considérable d'impacts négatifs : Perte de concentration, affaiblissement du système immunitaire, augmentation du risque de maladie cardio-vasculaire... Malgré ces chiffres, la médecine n'est pas armée pour soigner les personnes atteintes de ces troubles.
 +
  Dans le cas où l'origine est une maladie, les traitements vont seulement corriger les symptomes. Par exemple pour l'insomnie chronique, des somnifères vont être prescrits cependant l'origine ne sera pas traitée.
 +
 +
  iGEM Bordeaux 2016 propose de travailler sur un petit peptide, le DSIP, qui est un inducteur du sommeil naturellement produit par notre organisme qui semble faire ses preuves.
 +
  Pour comprendre dans quels mécanismes il est impliqués, nous voulons étudier ses effets sur le nématode <I>C. elegans</I> après l'avoir produit via la bactérie <I>E. coli</I>.
 +
  Parallèlement à ça, une étude des mécanismes du sommeil chez le nématode se fera par le biais du système CRISPR-méthylase pour venir inhiber ou activer les gènes impliqués dans ce processus.
 +
  Ce système dérive du système CRISPR-CAS9 que nous allons détourner pour en faire un outil d'épigénétique très précis.
 +
    -->
 +
 +
  <p align="center">Who has never suffered from sleep disorders ?</p>
 +
 +
  <p align="justify">A 2008 report of INPES, a French public institute, has shown that 45% of the 25-45 year-old population think that they do not sleep enough.
 +
  This lack causes a fair bit of negative impacts : focus decreasing, immune system weakening, increasing the risk of cardiovascular diseases...
 +
  Even if these statistics are high, today's medecine is not efficient enough when it comes to heal people suffering from sleep disorders. A classic example would be sleeping pills for chronic insomnia. Actually, they only treat the symptoms, not the source.</p>
 +
 +
  <p align="justify">iGEM Bordeaux 2016 team's subject of study is the DSIP, a sleep-inducing peptid which seems to be promising.
 +
  In order to understand in which mecanisms this peptid is involved, it will be produced by the E. coli bacteria as a bio factory and then given to a nematode called <I>C. elegans</I>.
 +
 +
  The sleeping process of this so called nematode will be studied using a CRISPR-methylase system, which is a modified CRISPR-CAS9, with the purpose of activating or deactivating genes participating in this process.
 +
  </p>
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<h2>Who are iGEM Bordeaux ?</h2>
 +
                    <p>We are 27 students from Bordeaux University and the engineering school ENSTBB.</p>
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<p> On behalf of the entire team, we would like to thank our sponsors for allowing us to build this project and present it at the 2016 edition of the Internationnal Genetically Engineered Machine competition!</p>
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                <h2>How to contact us ?</h2>
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                <p>Feel free to email us to provide some feedback on our project, have some informations on the team and our work, or to just say hello !</p>
 +
                <p><a href="mailto:igembdx@gmail.com">igembdx@gmail.com</a></p>
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Revision as of 11:49, 9 June 2016

Sleep with EpiC elegans
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Sleep with EpiC Elegans

Abstract

Who has never suffered from sleep disorders ?

A 2008 report of INPES, a French public institute, has shown that 45% of the 25-45 year-old population think that they do not sleep enough. This lack causes a fair bit of negative impacts : focus decreasing, immune system weakening, increasing the risk of cardiovascular diseases... Even if these statistics are high, today's medecine is not efficient enough when it comes to heal people suffering from sleep disorders. A classic example would be sleeping pills for chronic insomnia. Actually, they only treat the symptoms, not the source.

iGEM Bordeaux 2016 team's subject of study is the DSIP, a sleep-inducing peptid which seems to be promising. In order to understand in which mecanisms this peptid is involved, it will be produced by the E. coli bacteria as a bio factory and then given to a nematode called C. elegans. The sleeping process of this so called nematode will be studied using a CRISPR-methylase system, which is a modified CRISPR-CAS9, with the purpose of activating or deactivating genes participating in this process.

Who are iGEM Bordeaux ?

We are 27 students from Bordeaux University and the engineering school ENSTBB.


Come here and meet us!

Sponsors

On behalf of the entire team, we would like to thank our sponsors for allowing us to build this project and present it at the 2016 edition of the Internationnal Genetically Engineered Machine competition!



How to contact us ?

Feel free to email us to provide some feedback on our project, have some informations on the team and our work, or to just say hello !

igembdx@gmail.com

Copyright © iGEM Bordeaux 2016

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