Difference between revisions of "Team:ShanghaitechChina/HP/Gold"

 
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This year, our team applied the knowledge of synthetic biology to seek feasible solutions to the energy issue. Urgent as it is, the energy issue is more than a regional problem, but has raised global concerns. It is not just the difficulty we are now faced with, but the huge challenge that would greatly restrain the development of our future generations. Lots of researches and studies have been already devoted into the field. However, the challenge still remains, mainly due to the formidable gap between the research studies and the real industrial application. Thus, what our team wants to achieve is not only demonstrating our platform on the lab bench, but also gradually improving the system in the real social context. With this idea in minds, our team kept interacting with people from all walks of life, the industrial community, the academic experts, and the administrative governments, hearing their voice and learning from their comments.<p></p>
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This year, our team applied the knowledge of synthetic biology to seek feasible solutions to the energy issue. Urgent as it is, the energy issue is more than a regional problem, but has raised global concerns. It is not just the difficulty we are now faced with, but the huge challenge that would greatly restrain the development of our future generations. Lots of researches and studies have been already devoted into the field. However, the challenge still remains, mainly due to the formidable gap between the research studies and the real industrial application. Thus, what our team wants to achieve is not only <strong>demonstrating our platform on the lab bench, but also gradually improving the system in the real social context.</strong> With this idea in minds, <strong>our team kept interacting with people from all walks of life, the industrial community, the academic experts, and the administrative governments, hearing their voice and learning from their comments.</strong><p></p>
At the very early stage, when we were still brainstorming the idea, our team members actively talked to several top research groups all over the world. It was their insightful words that continuously stimulated our inspirations and promoted our improvements. Some of those groups have closely worked with photovoltaic materials for long; some of them are the leaders in electron transferring in organisms. Also, some of the team members have relatives working in the energy-related industry, so we took the advantages of these connections, searching for advices from an industrial aspect. Through these social dialogues, we not only discussed about the relevant technological operations; besides the team also learnt about the biggest obscures dragging the real application and industrialization with regards of the energy issue. Three criteria for a feasible solution were figured in the conversations, which are reasonable cost, satisfying efficiency, and the most importantly sustainability. With these objectives in heart, we thought over and over again during the whole research process to keep modifying the idea and make it more and more adaptable to the real industrial application. In assistance of these social interactions, lots of progresses and breakthroughs occurred, including the ultimate application of biofilm, a self-assemble, high-resistant, adhesive bio-material, which realize the relative high conductivity as well as the regenerative ability of the system.<p></p>
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<strong>At the very early stage, when we were still brainstorming the idea, our team members actively talked to several top research groups all over the world. It was their insightful words that continuously stimulated our inspirations and promoted our improvements</strong>. Some of those groups have closely worked with photovoltaic materials for long; some of them are the leaders in electron transferring in organisms. Also, some of the team members have relatives working in the energy-related industry, so we took the advantages of these connections, searching for advices from an industrial aspect. Through these social dialogues, we not only discussed about the relevant technological operations; besides the team also learnt about the biggest obscures dragging the real application and industrialization with regards of the energy issue. Three criteria for a feasible solution were figured in the conversations, which are reasonable cost, satisfying efficiency, and the most importantly sustainability. With these objectives in heart, we thought over and over again during the whole research process to keep modifying the idea and make it more and more adaptable to the real industrial application. In assistap4nce of these social interactions, lots of progresses and breakthroughs occurred, including <strong>the ultimate application of biofilm, a self-assemble, high-resistant, adhesive bio-material, which realize the relative high conductivity as well as the regenerative ability of the system.</strong><p></p>
Then, soon after we finished the first version of the project, “Solar Hunter I”, we proposed and conducted a public questionnaire, where we further learnt about the public attitude towards the energy issue as well as our project. A serious of general and detailed topics was investigated. From the analysis of the questionnaire, we learnt the biggest two public concerns of the wide application of hydrogen, that was safety and expense. Also, further communications with the industrial community, the academic experts, and the responsible authority were suggested as well.<p></p>
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Then, soon after we finished the first version of the project, “Solar Hunter I”, <strong>we proposed and conducted a public questionnaire</strong>, where we further learnt about the public attitude towards the energy issue as well as our project. A serious of general and detailed topics was investigated. From the analysis of the questionnaire, we learnt the biggest two public concerns of the wide application of hydrogen, that was safety and expense. Also, <strong>further communications with the industrial community, the academic experts, and the responsible authority were suggested as well</strong>.<p></p>
In response to the subsequent need for further field investigation from various angles, our team then carried out a series of interviews with people working with the energy issue but from different points of view. Not only did we continue to be connected with more and more field experts academically, but also we spared plenty of time and efforts to be in touch with people in the industrial community as well as the government. Through the talks and discussions, we further developed the understanding on the mainstream opinions with regards of the safety concern for hydrogen application both academically and industrially. As those field experts replied, benefiting from some of the characteristics hydrogen possessed, including low density nontoxicity, and zero pollutant emission, hydrogen demonstrated terrific potential as an ideal energy source. Also, with those mature techniques in hydrogen transport and storage, the safety concern is not necessary. However, in terms of the industrial application, most of them laid strong emphasis on the applicability, efficiency, expense and the sustainability about our platform. Reminded by these conversations, our team further considered our system in the context of real industrial use. After a series of brainstorming, we planned to try another co-culture approach where the anaerobic condition was not necessary, instead of the original strategy that extracted the target protein directly. With this improvement, our platform was able to operate under normal aerobic environment, where the manufacture would be much easier and also obviously cost less. Moreover, attracted by our passion as well as the feasible idea, future collaboration with these industrial companies and the local authority would be very likely to be put into real actions later on.<p></p>
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In response to the subsequent need for further field investigation from various angles, our team then carried out a series of interviews with people working with the energy issue but from different points of view. Not only did we continue to be connected with more and more field experts academically, but also we spared plenty of time and efforts to be in touch with people in the industrial community as well as the government. Through the talks and discussions, we further developed the understanding on the mainstream opinions with regards of the safety concern for hydrogen application both academically and industrially. As those field experts replied, benefiting from some of the characteristics hydrogen possessed, including low density nontoxicity, and zero pollutant emission, hydrogen demonstrated terrific potential as an ideal energy source. Also, with those mature techniques in hydrogen transport and storage, the safety concern is not necessary. However, in terms of the industrial application, most of them laid strong emphasis on the applicability, efficiency, expense and the sustainability about our platform. Reminded by these conversations, our team further considered our system in the context of real industrial use. <strong>After a series of brainstorming, we planned to try another co-culture approach where the anaerobic condition was not necessary, instead of the original strategy that extracted the target protein directly.</strong> With this improvement, our platform was able to operate under normal aerobic environment, where the manufacture would be much easier and also obviously cost less. Moreover, attracted by our passion as well as the feasible idea, future collaboration with these industrial companies and the local authority would be very likely to be put into real actions later on.<p></p>
Later on, when we demonstrated the project to some of these field experts again, they were pretty impressed by our soon improvements. As they commented, our new system demonstrated huge potential in massive industrial application. For the next step, they suggested us to work more on the efficiency. Since the electron transfer operated as key step in our system, we then tried to cultivate the biofilm on some small beads, increasing the contact area to achieve a better efficiency. Also, with the application of these small beads, the NRs attached on the biofilm were more easily to be collected and recycled, simply by spinning down the beads.<p></p>
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Later on, when we demonstrated the project to some of these field experts again, they were pretty impressed by our soon improvements. As they commented, our new system demonstrated huge potential in massive industrial application. For the next step, they suggested us to work more on the efficiency. <strong>Since the electron transfer operated as key step in our system, we then tried to cultivate the biofilm on some small beads, increasing the contact area to achieve a better efficiency. Also, with the application of these small beads, the NRs attached on the biofilm were more easily to be collected and recycled, simply by spinning down the beads</strong>.<p></p>
 
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<h1 align="center">Brief Time Line</h1>
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1. Social investigation on background as well as brief counseling with field experts. <p></p>
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2. Finalization of the topic we plan to work on, the energy issue. <p></p>
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3. Further talks with field experts. <p></p>
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4. The application of biofilm. <p></p>
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5. Public Questionnaire. <p></p>
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6. Interviews with people from different aspects. <p></p>
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7. The application of the co-culture system. <p></p>
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8. Further social talks and connections. <p></p>
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9. The application of biofilm coated beads. <p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Silver">You can click here to learn more about the analysis on the questionnaire.</a><p></p>
 
<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Silver">You can click here to learn more about the analysis on the questionnaire.</a><p></p>
 
Meanwhile, in response to the strong necessity to get connected with the industrial, the academics, and the authority, so as to better promote and prepare for the real industrialization, a series of interviews from various aspects were carried out. Our interviewees included scientists exploring in energy field, industrial representatives dedicating to the energy conservation, as well as administrative officers from the relevant governmental departments. Some of the representative interviews were displayed on the page.<p></p>
 
Meanwhile, in response to the strong necessity to get connected with the industrial, the academics, and the authority, so as to better promote and prepare for the real industrialization, a series of interviews from various aspects were carried out. Our interviewees included scientists exploring in energy field, industrial representatives dedicating to the energy conservation, as well as administrative officers from the relevant governmental departments. Some of the representative interviews were displayed on the page.<p></p>
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To sum up, <strong>it is the real time social interactions with various aspects guiding us to gradually improve the project adjusting the system to be closer and closer to the real industrialization</strong>. This is just the true essence lying behind the Human Practice.
 
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<strong>Interview with Professor Qixi Mi</strong>
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<strong>Interview with Professor Qixi Mi</strong><p></p>
 
We met Professor Mi (Qixi Mi), assistant professor from the school of physical science and technology at ShanghaiTech University. Prof. Mi earned his B.S. degree from Peking University in applied chemistry in 2003 and his Ph.D. degree from Northwestern University in chemistry in 2009. Later he performed postdoctoral research on new souse energy at California Institute of Technology, taking advantage of a fellowship of the NSF Center for Chemical Innovation (CCI Solar), and then briefly at the Argonne–Northwestern Solar Energy Research (ANSER) Center.<p></p>
 
We met Professor Mi (Qixi Mi), assistant professor from the school of physical science and technology at ShanghaiTech University. Prof. Mi earned his B.S. degree from Peking University in applied chemistry in 2003 and his Ph.D. degree from Northwestern University in chemistry in 2009. Later he performed postdoctoral research on new souse energy at California Institute of Technology, taking advantage of a fellowship of the NSF Center for Chemical Innovation (CCI Solar), and then briefly at the Argonne–Northwestern Solar Energy Research (ANSER) Center.<p></p>
 
Firstly, team delegation asked about the reasons that guided Pro. Mi to devote himself to the energy research field. As Pro. Mi responded, without any doubt, the energy issue was one of the biggest global challenges we mankind were facing and urgently needed to be solved. The significance of the relevant researches and studies were emphasized in terms of the sustainable development for the whole industry, because the energy source was the very fundamental matters of all sorts of industrial productions. Then, speaking of the possible solutions to the energy issue, Pro. Mi emphasized the importance of the utilization of the solar energy for the sun was the ultimate way that we human beings could get sustainable source of energy. As he further stated, thanks to the development of the modern technologies, for now lots of simi-conductive materials people had discovered showed a relative high efficiency to collect sun light. However the central problems laid on how to efficiently utilize that solar energy we collected. Similar to what we applied in our project, Pro. Mi considered hydrogen gas as a good choice for the solar energy conversion. With its high molecular energy density as well as the simple chemical constituents, hydrogen demonstrated ideal characteristics to be an energy source. Also, without the participation of the carbon, the only product of the combustion of hydrogen was only water which had no side effect to the environment. This made hydrogen the complete clean energy source.<p></p>
 
Firstly, team delegation asked about the reasons that guided Pro. Mi to devote himself to the energy research field. As Pro. Mi responded, without any doubt, the energy issue was one of the biggest global challenges we mankind were facing and urgently needed to be solved. The significance of the relevant researches and studies were emphasized in terms of the sustainable development for the whole industry, because the energy source was the very fundamental matters of all sorts of industrial productions. Then, speaking of the possible solutions to the energy issue, Pro. Mi emphasized the importance of the utilization of the solar energy for the sun was the ultimate way that we human beings could get sustainable source of energy. As he further stated, thanks to the development of the modern technologies, for now lots of simi-conductive materials people had discovered showed a relative high efficiency to collect sun light. However the central problems laid on how to efficiently utilize that solar energy we collected. Similar to what we applied in our project, Pro. Mi considered hydrogen gas as a good choice for the solar energy conversion. With its high molecular energy density as well as the simple chemical constituents, hydrogen demonstrated ideal characteristics to be an energy source. Also, without the participation of the carbon, the only product of the combustion of hydrogen was only water which had no side effect to the environment. This made hydrogen the complete clean energy source.<p></p>
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Aiming at spreading the iGEM as well as contributing to the local community, ShanghaiTech iGEM Day for Public Interests (iDPI) was found in 2016, along with the establishment of the first ever iGEM team at ShanghaiTech University. The iDPI at ShanghaiTech is set up to encourage every iGEM team to dedicate themselves not only into scientific researches, but also social practices. Sciences and technologies are used to serve people and the society; therefore the awareness to contribute to the social interests is of equal importance with the research explorations. In the acronym name iDPI, “D” stands for dedication, “P” stands for passion, and “I” stands for inspiration. Our hope is that with the establishment of iDPI, every iGEMer at ShanghaiTech would bear a strong social awareness in minds, to yield profound contributions and achieve social values.<p></p>
 
Aiming at spreading the iGEM as well as contributing to the local community, ShanghaiTech iGEM Day for Public Interests (iDPI) was found in 2016, along with the establishment of the first ever iGEM team at ShanghaiTech University. The iDPI at ShanghaiTech is set up to encourage every iGEM team to dedicate themselves not only into scientific researches, but also social practices. Sciences and technologies are used to serve people and the society; therefore the awareness to contribute to the social interests is of equal importance with the research explorations. In the acronym name iDPI, “D” stands for dedication, “P” stands for passion, and “I” stands for inspiration. Our hope is that with the establishment of iDPI, every iGEMer at ShanghaiTech would bear a strong social awareness in minds, to yield profound contributions and achieve social values.<p></p>
This year, iDPI collaborated with Shanghai Coordinate International School, holding an iGEM Lab Open House Day on Zhangjiang campus. The activity took place in the early September. At noon time, alone with another iGEM team at ShanghaiTech, our iGEM team members warmly welcomed the visiting delegation from Shanghai Coordinate International School at the conference room. Leaded by Dr. (Name), a leading science teacher at the Coordinate, the delegation consisted of 8 high school students from different grades.<p></p>
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This year, iDPI collaborated with Shanghai Coordinate International School, holding an iGEM Lab Open House Day on Zhangjiang campus. The activity took place in the early September. At noon time, along with another iGEM team at ShanghaiTech, our iGEM team members warmly welcomed the visiting delegation from Shanghai Coordinate International School at the conference room. Leaded by Teacher Gordon, a leading science teacher at the Coordinate, the delegation consisted of 8 high school students from different grades.<p></p>
An introduction speech to the ShanghaiTech was first delivered by the team member Haolong. Then he continued to further talked about the background of iGEM as well as synthetic biology. After that, delegates from two of the iGEM team conducted a brief presentation on the iGEM project subsequently. Finally an open discussion session was held, where the high school students demonstrated strong interests about synthetic biology and actively asked questions about the iGEM and our projects. Some of them even showed strong willingness to participate in the iGEM in the following year. As we responded at the meeting, we would be very happy to try to provide all sorts of assistance they may need to build up their own high school team for the iGEM. Also, if any of they were interested in real experience of hand-on lab operations, our iGEM lab was always open to them to visit and explore. Additionally, last week we were just informed by (Name) that their school would be very likely to build up their first-ever high school iGEM team; hopefully they may officially participate in the competition in the following years. We would keep providing them sufficient assistance and support as long as necessary.<p></p>
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An introduction speech to the ShanghaiTech was first delivered by the team member Haolong. Then he continued to further talked about the background of iGEM as well as synthetic biology. After that, delegates from two of the iGEM team conducted a brief presentation on the iGEM project subsequently. Finally an open discussion session was held, where the high school students demonstrated strong interests about synthetic biology and actively asked questions about the iGEM and our projects. Some of them even showed strong willingness to participate in the iGEM in the following year. As we responded at the meeting, we would be very happy to try to provide all sorts of assistance they may need to build up their own high school team for the iGEM. Also, if any of they were interested in real experience of hand-on lab operations, our iGEM lab was always open to them to visit and explore. Additionally, last week we were just informed by Teacher Gordon that their school would be very likely to build up their first-ever high school iGEM team; hopefully they may officially participate in the competition in the following years. We would keep providing them sufficient assistance and support as long as necessary.<p></p>
 
After the speech and discussion, a lab visiting was scheduled as the second session of the Open House Day. Our team members paired with the visiting high school students, guiding them around the research center at school. We introduced the equipment to them one by one, from the cell disruptor to the ultra-centrifuge, from the FACS to TEM, explaining the mechanisms behind in popular and easy-to-understand language. Part of our lab results were demonstrated as well, so as to help them build a better understanding on our projects.<p></p>
 
After the speech and discussion, a lab visiting was scheduled as the second session of the Open House Day. Our team members paired with the visiting high school students, guiding them around the research center at school. We introduced the equipment to them one by one, from the cell disruptor to the ultra-centrifuge, from the FACS to TEM, explaining the mechanisms behind in popular and easy-to-understand language. Part of our lab results were demonstrated as well, so as to help them build a better understanding on our projects.<p></p>
 
The Open House Day ended around 6 in the evening. As one of the visiting students commented, this lab tour was very impressive and amazing which greatly aroused his curiosity to explore the secrets of nature. And this was just the core value shared by iDPI to pass the knowledge and inspire the interests to the next young generations.<p></p>
 
The Open House Day ended around 6 in the evening. As one of the visiting students commented, this lab tour was very impressive and amazing which greatly aroused his curiosity to explore the secrets of nature. And this was just the core value shared by iDPI to pass the knowledge and inspire the interests to the next young generations.<p></p>
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       <h1 align="center">Movie</h1>
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       <h1 align="center">Self-developed Movie for Propagation Purpose</h1>
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To better illustrate our strategy and mechanism behind the Solar Hunter, our team self designed, filmed and edited a movie. The movie can be viewed in the following to help you build a better understanding on our project.<p></p>
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Meanwhile, this video is used as propagational and educational tools to spread the iGEM competition as well as synthetic biology. Multimedia approach is undoubtedly the best way to arouse interests when it comes to the young generations. Through our efforts, we expect more and more people, especially young kids could know deeper about synthetic biology, eventually resulting in more social contributions and significance.<p></p>
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Movie<p></p>
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<p></p>*Along with the HP Page for Silver Award, this page is designed according to the requirement on Human Practice for Gold Award.
 
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Latest revision as of 03:28, 20 October 2016

igem2016:ShanghaiTech