Difference between revisions of "Team:ShanghaitechChina/Human Practice"

 
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Thinking beyond laboratory is one of the key factors that would affect the yield of scientific researches into real social interests. Thankfully, this idea has been recognized by the iGEM community for a very long time. Not only should every team participate in various social activities, but also we need to keep a real time interaction with the society, the place that we ultimately hope to create magnificence.<p></p>
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<h1 align="center">Human Practice Overview</h1>
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This year, our team applied the knowledge of synthetic biology to seek feasible solutions to the energy issue. Urgent as it is, the energy issue is more than a regional problem, but has raised global concerns. It is not just the difficulty we are now faced with, but the huge challenge that would greatly restrain the development of our future generations. Lots of researches and studies have been already devoted into the field. However, the challenge still remains, mainly due to the formidable gap between the research studies and the real industrial application. Thus, what our team wants to achieve is not only demonstrating our platform on the lab bench, but also gradually improving the system in the real social context. With this idea in minds, our team kept interacting with people from all walks of life, the industrial community, the academic experts, and the administrative governments, hearing their voice and learning from their comments.<p></p>
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At the very early stage, when we were still brainstorming the idea, our team members actively talked to several top research groups all over the world. It was their insightful words that continuously stimulated our inspirations and promoted our improvements. Some of those groups have closely worked with photovoltaic materials for long; some of them are the leaders in electron transferring in organisms. Also, some of the team members have relatives working in the energy-related industry, so we took the advantages of these connections, searching for advices from an industrial aspect. Through these social dialogues, we not only discussed about the relevant technological operations; besides the team also learnt about the biggest obscures dragging the real application and industrialization with regards of the energy issue. Three criteria for a feasible solution were figured in the conversations, which are reasonable cost, satisfying efficiency, and the most importantly sustainability. With these objectives in heart, we thought over and over again during the whole research process to keep modifying the idea and make it more and more adaptable to the real industrial application. In assistance of these social interactions, lots of progresses and breakthroughs occurred, including the ultimate application of biofilm, a self-assemble, high-resistant, adhesive bio-material, which realize the relative high conductivity as well as the regenerative ability of the system.<p></p>
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Then, soon after we finished the first version of the project, “Solar Hunter I”, we proposed and conducted a public questionnaire, where we further learnt about the public attitude towards the energy issue as well as our project. A serious of general and detailed topics was investigated. From the analysis of the questionnaire, we learnt the biggest two public concerns of the wide application of hydrogen, that was safety and expense. Also, further communications with the industrial community, the academic experts, and the responsible authority were suggested as well.<p></p>
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In response to the subsequent need for further field investigation from various angles, our team then carried out a series of interviews with people working with the energy issue but from different points of view. Not only did we continue to be connected with more and more field experts academically, but also we spared plenty of time and efforts to be in touch with people in the industrial community as well as the government. Through the talks and discussions, we further developed the understanding on the mainstream opinions with regards of the safety concern for hydrogen application both academically and industrially. As those field experts replied, benefiting from some of the characteristics hydrogen possessed, including low density nontoxicity, and zero pollutant emission, hydrogen demonstrated terrific potential as an ideal energy source. Also, with those mature techniques in hydrogen transport and storage, the safety concern is not necessary. However, in terms of the industrial application, most of them laid strong emphasis on the applicability, efficiency, expense and the sustainability about our platform. Reminded by these conversations, our team further considered our system in the context of real industrial use. After a series of brainstorming, we planned to try another co-culture approach where the anaerobic condition was not necessary, instead of the original strategy that extracted the target protein directly. With this improvement, our platform was able to operate under normal aerobic environment, where the manufacture would be much easier and also obviously cost less. Moreover, attracted by our passion as well as the feasible idea, future collaboration with these industrial companies and the local authority would be very likely to be put into real actions later on.<p></p>
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Later on, when we demonstrated the project to some of these field experts again, they were pretty impressed by our soon improvements. As they commented, our new system demonstrated huge potential in massive industrial application. For the next step, they suggested us to work more on the efficiency. Since the electron transfer operated as key step in our system, we then tried to cultivate the biofilm on some small beads, increasing the contact area to achieve a better efficiency. Also, with the application of these small beads, the NRs attached on the biofilm were more easily to be collected and recycled, simply by spinning down the beads.<p></p>
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Additionally, while conducting our research with the interaction in the social context, our team also participated in a variety of educational propagation and public engagements. As the first-ever iGEM team at ShanghaiTech, this year we established the iGEM Day for Public Interests (iDPI), where we held a Lab Open House Day for the visiting high school student from Shanghai Coordinate International School, aiming at arousing their interests in science, especially in synthetic biology. Meanwhile, we introduced the iGEM to them as well, and are now helping them to build their first-ever high school team. Besides, out team collaborated another two iGEM team in China, one at Jiangsu Normal University, and the other at Tsinghua University. <p></p>
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For more details about our Human Practice and Social Engagements, please find the following pages as well as the attached links.<p></p>
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https://2016.igem.org/Team:ShanghaitechChina/HP/Silver
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Thinking beyond laboratory is one of the key factors that would affect the yield of scientific researches into real social interests. Thankfully, this idea has been recognized by the iGEM community for a very long time. Not only should every team participate in various social activities, but also we need to keep a real time interaction with the society, the place that we ultimately hope to create significance.<p></p>
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   As we described in the introduction and background session, the importance and urgency to work on the energy issue is obvious. The energy issue is neither just a regional nor national problems, but instead a global. In response to the urgent need, lots of scientific researches have devoted vast efforts and time to those relevant studies, however, only few of which are really able to be put into real usage. Therefore, the key issue for the energy issue is not only the technological advancements, but also the awareness to integrate the scientific results into industrial application to yield concrete social values. With this idea in mind that also accord with the requirements for iGEM Human Practice, this year our team conducted the social research on the energy issue, along with our biofilm based artificial photosynthesis platform.<p></p>
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This year, our team applied the knowledge of synthetic biology to seek feasible solutions to the energy issue. Urgent as it is, the energy issue is more than a regional problem, but has raised global concerns.  In this social context, converting solar energy into chemical energy is undoubtedly of fundamental and industrial importance. Our original interest on this topic was initially sparked by recent cutting-edge research in artificial photosynthesis. To enhance our understandings about energy issues, and meanwhile, arouse public awareness of synthetic biology, we raised multiple public questionnaires and dialogues within academe and industry. In communications with industrial community, field experts as well as administrative authority afterwards, we realized that development of a robust, sustainable and scalable approach for hydrogen production would be socially relevant, industrially important, but technically challenging. This has led us to set our ultimate goals to solve such challenge by leveraging the power of synthetic biology. We eventually proposed and demonstrated a sun-powered biofilm-interfaced artificial hydrogen-producing system, Solar Hunter. Benefiting from the real time social interactions, we kept modifying the system to be more and more adaptable to the scalable industrial application. This new system will in return, introduce a synthetic biology-based approach towards energy applications in industrial context.<p></p>
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The main objectives of this social research aim at socially figuring out the background information of the energy issue as well as getting prepared for the further industrialization of our project. To understand the situation more comprehensively, we want to hear various point of views from different aspects, the public, the academic, the industrial, and also the authority. Only when opinions from all these parties are heard, could we fully understand the issue in reality and then figure out a series of feasible solutions to contribute to our society.<p></p>
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Additionally, while conducting the research, our team not only kept real-time interactions with the society regarding to the project itself, but also we actively participated in a variety of educational propagation and public engagements. As the first-ever iGEM team at ShanghaiTech, this year we established the iGEM Day for Public Interests (iDPI), a special social activity for every iGEMers at ShanghaiTech. For this year’s iDPI, a Lab Open House Day was held where delegating high school students from Shanghai Coordinate International School paid a visit, aiming at arousing their interests in science, especially in synthetic biology. Moreover, we introduced the iGEM to them during the day, and are now helping them to build up their first-ever high school team for the future iGEM. Besides, this year our team closely collaborated with two iGEM teams in China, JSNU-China at Jiangsu Normal University and Tsinghua-A at Tsinghua University.<p></p>
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This social research were performed briefly in two parts, public questionnaire and interviews. A public questionnaire was firstly implemented to collect general information from the public. Then, we carefully analyzed the data collected. And according to the main concerns and opinions we found through the questionnaire, experts from different walk of life were invited to participate in the interview. Our interviewees included scientists working at the cutting-edge in the field, industrial representatives dedicating to the energy conservation, as well as from the administrative government. With the participation of not only the public and the academic, but also the industrial and the authority, we deeply explored the social background to prepare to integrate and industrialize our project as well as built up necessary social connections for the future supports. <p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Gold">Click here to find our Integrated Human Practice.</a>
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<h1 align="center"> Social Research on the Energy Issue </h1>
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In response to the strong necessity to get connected with the industrial, the academics, and the authority, so as to better promote and prepare for the real application and integration of our energy conversion platform and sever the mankind, a series of interviews with the industrial community, academic scientists, and administration and supervision departments were carried out. Taking the chance here, our team would like to extend our sincere gratitude to all those individuals and groups for their assistance and cooperation.
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<h2 align="center">Background & Introduction </h2>
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As previously addressed, the importance and urgency to seek a feasible solution to the energy issue is undebatable. The energy issue is neither just a regional nor national problem, but instead a global one. In response to the urgent need, vast efforts and time have already been devoted to those relevant studies, however, only few of which is really able to be put into real applications. Actually, the biggest obscure restraining the feasible solution to alleviate the energy stress is mainly due to the huge gap between the research results and the massive industrialization. In another word, not only should we emphasize the technological advancements, but also we ought to raise a strong awareness to integrate the scientific results into real industrial application to yield concrete social values.<p></p>  
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Established in 1985, Shanghai Energy Conservation Association (SECA) is a membership non-profitable organization that works on the sustainable energy development on behalf of the industrial firms. Most of the local industrial companies, including those very influential ones like Bao Steel, are the members of the association. The SECA is set for the potential industrial collaborations with regards of the energy issue, whose main duties include the industrialization of new energy technologies as well as the propagation of the idea of energy conservation. Most employees working at SECA, including the interviewee, previously worked in the real industry. With their sufficient experience in the field, and also benefits from their daily cooperation with industrial partners, the SECA is undoubtedly an excellent place for our team to seek more insights from the industrial point of view. Also, the comments from the SECA would be of great importance for the industrialization and scale application of our project to yield more social interests.<p></p>
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To understand the energy issue from a border aspect, our team carried out a social research discovering the gap between the academic research and the industrial application, especially in the context of the energy issue. The main objectives of this social research aim at socially figuring out the relevant background as well as getting the project prepared for the further industrialization. We hope to hear various opinions from different aspects, or to be concrete not only the public and the academic, but also the industrial and the authority. Only when we understand comprehensively, could we figure out a series of feasible solutions in the social context, to profoundly contribute to the world.<p></p>
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Our delegation visited the SECA in August, 2016, where we also organized an interview with Mr. Lan (Yujun Lan), director of the expert committee at SECA, and Ms. Chen (Meijuan Chen), vise director of the expert committee at SECA.<p></p>
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Our social research started as early as we just decided to work on the energy issue. We built up a long-term real-time interaction with the society, instead of just a simple glimpse, for the comprehensive understanding on the issue required continuous communications and thoughts exchanging. Generally speaking, this social research consisted of two main parts, the public questionnaire and interviews. The public questionnaire was implemented to be familiar with the general public attitudes. We carefully analyzed the data collected, and according to the main concerns and opinions we found through the data analysis, we then invited several experts from different walks of life to participate in the following theme interviews. Our interviewees included scientists working at the cutting-edge in the field, industrial representatives dedicating to the energy conservation, as well as from the administrative government. With their generous engagements, our team was able to further explore the project in a social context.<p></p>
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At the beginning of the meeting, team member Haolong delivered an brief introduction to our project first. Both Mr. Lan and Ms. Chen were deeply impressed by our dauntless but creative idea. As they commented, they had served for the energy industry for decades, but this was the very first time they heard about using biological platform to provide new energy source as hydrogen gas. From an industrial point of view, they could tell the great future potential and feasibility our project suggested to be further developed into real industrial application in a big scale, meanwhile they also point out that some modifications especially with regards of the working conditions as well as an adaptation to the flow line production would be necessary. Besides, as Mr. Lan further said, the mission of the SECA included the promotion and industrialization of new technology, with their abundant experience in the field, they were willing to assist our team to continuously modify the project and try to put it into industrial application. <p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Silver">Click here to know more about our social research.</a><p></p>
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Then, Mr. Lan and Ms. Chen briefly talked about the daily operation of the SECA. Additional to the modulation of the membership industrial companies that resulted in a series of collaborations, socially popularizing and promoting the idea of energy conservation was also one of their core objectives. Through their efforts, they were looking for a gradual improvement of social awareness of the energy issus, espceially among the young age group. Annually, a variety of theme activities were held by the SECA to achieve the goal. Every year, there is an Energy Awareness Week took place in Shanghai where the representative industrial delegates were invited to introduce their cutting edge energy technologies to the public, in communities, schools, or exhibitions. Mr. Lan warmly welcomed and invited our team to participate in the next year’s theme week. We were so much sure that this special chance would be an awesome opportunity for our team to not only further socialize and industrialize the project, but also integrate our own efforts into real social needs.<p></p>
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Finally, Mr Lan. And Ms. Chen again emphasized the creativity and huge potential of our project from an industrial aspect. They encouraged us to modulate in details and step further. They were willing to provide any necessary assistance from the industrial community.<p></p>
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A questionnaire about the energy issue was designed and then distributed online. In all, 37 questions were asked, and here, we performed the core analysis on the data we collected. We had eventually collected 231 samples, 15 of which were cancelled as invalid samples due to their short answering time (less than 180 seconds). The rest of 216 samples were regarded as valid responds that qualified for further analysis.<p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Silver#p3">Click here to view detailed questionnaire analysis.</a>
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To deeply understand the energy issue from various aspects as well as further develop our system in the real social context, our team conducted a series of interviews with experts from all walks of life. Besides the general voices heard from the public, we discovered the opinions from the relevant industrial communit, the academic researchers and the administrative authority.<p></p>
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Our interviewees include the following: <p></p>
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Professor Qixi Mi from School of physical science and technology at ShanghaiTech University;<p></p>
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Researcher Fei Yu from CAS Key Laboratory of Low-Carbon Conversion Science and Engineering;<p></p>
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Mr. Yujun Lan from Shanghai Energy Conservation Association (SECA);<p></p>
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Ms. Chen from Shanghai Energy Conservation Association (SECA);<p></p>
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Ms. Yu Huang from Shanghai Environment and Energy Exchange CO., LTD;<p></p>
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Mr. Shengbo Chen from Shanghai Environment and Energy Exchange CO., LTD;<p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Gold#p3">Click here to find further information about our interviews.</a>
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This year, our team actively collaborated with two iGEM teams in China, which are the team Tsinghua-A from Tsinghua University and the JSNU-China from Jiangsu Normal University. The team Tsinghua-A focused on constructing a synthetic biology circuit to seek insights into noise propagation as well as measuring the capacity of parallel information channels. Our team members, Lechen Qian and Haolong Zhu, helped them to gain access to a better home-built computation platform, applied their knowledge to modify and operate the algorithm, and scanned two key parameters, Ka (dimer association rate) and Kd (dimer dissociation rate constant) relevant to their modeling project in use of Gillespie Algorithm. Meanwhile, we also helped JSNU-China from Jiangsu Normal University to culture a hela cell clone (the ninth generation) in our culture facility, which later on became an indivisible part in their project and gave them new thinking about utilizing new cell lines. We also benefited a lot through multiple interactions with the two teams during team collaboration. <p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/Collaborations">Click here for more details about our team collaborations.</a><p></p>
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<a href="https://2016.igem.org/Team:JSNU-China/Collaborations">Click here to see our assistance reported by the iGEM team at Jiangsu Normal University.</a><p></p>
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<a href="https://2016.igem.org/Team:Tsinghua-A/Collaborations">Click here to see our assistance reported by the iGEM team at Tsinghua University.</a><p></p>
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Aiming at spreading the iGEM as well as dedicating to various  social engagements, ShanghaiTech iGEM Day for Public Interests (iDPI) was found in 2016, along with the establishment of the first ever iGEM team at ShanghaiTech University. The iDPI at ShanghaiTech is set up to encourage every iGEM team to devote themselves not only into advanced scientific researches, but also active social practices.<p></p>
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In the acronym name iDPI, “D” stands for dedication, “P” stands for passion, and “I” stands for inspiration. We expect that with the establishment of iDPI, every iGEMer at ShanghaiTech would bear a strong social awareness in mind, yielding profound contributions and achieving valuable social interests.<p></p>
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This year, the iDPI collaborated with Shanghai Coordinate International School, holding an iGEM Lab Open House Day on Zhangjiang campus.<p></p>
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<a href="https://2016.igem.org/Team:ShanghaitechChina/HP/Gold#p5">Click here for more details about iDPI.</a>
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          <h1 align="center">iDPI</h1>
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      <h1 align="center">Self-developed Movie for Propagation Purpose</h1>
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https://2016.igem.org/Team:ShanghaitechChina/Collaborations <p></p>
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To better illustrate our strategy and mechanism behind the Solar Hunter, our team self designed, filmed and edited a movie. The movie can be viewed in the following to help you build a better understanding on our project.<p></p>
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      </div>
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Meanwhile, this video is used as propagational and educational tools to spread the iGEM competition as well as synthetic biology. Multimedia approach is undoubtedly the best way to arouse interests when it comes to the young generations. Through our efforts, we expect more and more people, especially young kids could know deeper about synthetic biology, eventually resulting in more social contributions and significance.<p></p>
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<div class="col-lg-6">
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</div>
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<img src="https://static.igem.org/mediawiki/2016/c/cf/Stu_%289%29.jpg" style="width:100%;">
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      <div class="col-lg-12">
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</div>
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<div class="col-lg-6">
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<video data-anchor-target="#vi" src="https://static.igem.org/mediawiki/2016/6/64/T--ShanghaitechChina--SolarHunter2.mp4
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<img src="https://static.igem.org/mediawiki/2016/a/ab/Stu_%2810%29.JPG" style="width:100%;">
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</div>
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" width="75%" style="margin-top:3%;margin-left:13%" controls="controls">
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</div>
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</video>
 +
      </div>  
 +
  </div>
 
</div>
 
</div>
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<script>
 
<script>
 
$('.pic3x').click(function(){
 
$('.pic3x').click(function(){

Latest revision as of 12:46, 1 December 2016

igem2016:ShanghaiTech