Difference between revisions of "Team:CGU Taiwan"

 
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{{CGU_Taiwan}}
 
 
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<html>
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<h2> Welcome to iGEM 2016! </h2>
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<head>
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
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<style>
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body {
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</head>
  
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<script>
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<h5>Before you start: </h5>
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/* Dynamic top menu positioning
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<p> Please read the following pages:</p>
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*
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*/
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<li>  <a href="https://2016.igem.org/Requirements">Requirements page </a> </li>
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var num = 110; //number of pixels before modifying styles
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<li> <a href="https://2016.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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$(window).bind('scroll', function () {
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<li> <a href="https://2016.igem.org/Resources/Template_Documentation"> Template Documentation </a></li>
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    if ($(window).scrollTop() > num) {
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</ul>
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        $('.header-subnav').addClass('fixed1');
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<div class="highlight">
 
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<h5> Styling your wiki </h5>
 
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
 
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
 
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</div>
 
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<div class="column full_size" >
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//USE SCROLL WHEEL FOR THIS FIDDLE DEMO
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<h5> Wiki template information </h5>
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</script>
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<p>We have created these wiki template pages to help you get started and to help you think about how your team will be evaluated. You can find a list of all the pages tied to awards here at the <a href="https://2016.igem.org/Judging/Pages_for_Awards/Instructions">Pages for awards</a> link. You must edit these pages to be evaluated for medals and awards, but ultimately the design, layout, style and all other elements of your team wiki is up to you!</p>
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</div>  
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<body>
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<a name='anchor1'></a>
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<div class="top">
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<img style="margin-top:-2%;width:100%;height:140%;position:absolute;" src="https://static.igem.org/mediawiki/2016/0/0b/CGU_Taiwan--top.jpg">
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</div>
  
 +
<header class="top">
 +
    <div class="header-subnav">
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan">HOME</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Achievements">ACHIEVEMENTS</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Description">PROJECT</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Software">MODELING</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Human_Practices">HUMAN PRACTICES</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Team">PEOPLE</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Interlab">INTERLAB</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Safety">SAFETY</a></li>
 +
    <li><a href="https://2016.igem.org/Team:CGU_Taiwan/Parts">PARTS</a></li>
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  </div>
 +
</header>
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<br><br><br>
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<div>
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<br><br><br><br>
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<video margin-top="5%" width="100%" height="700px" controls  autoplay>
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<source src="https://static.igem.org/mediawiki/2016/4/41/CGU_Taiwan--video4.mp4" type="video/mp4">
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</video>
 +
</div>
  
 +
<br><br><br>
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<div class="mid">
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<div style="font-size:60px;color:#140731;text-decoration:none;margin-left:45%;">
 +
<br><br><br><br>
 +
Abstract
 +
</div>
 +
<br></br>
 +
<br></br>
 +
<b style="color:black;font-size:25px;margin-left:10%;">Leijuvant- A Revolutionary Choice of Vaccine Helper</b><br><br>
 +
<div style="color:black;font-size:18px;margin-left:10%;text-align:justify;">
 +
For many infectious diseases that still don’t have an effective vaccine, enhancing T cell immune response may be the key point to solve this problem. Leijuvant represents a whole new perspective of adjuvant that uses Leishmania as an effective T cell stimulator. Leishmania is a parasite that specifically lives within macrophage, a professional antigen presenting cell (APC). As a potential vaccine adjuvant, Leishmania possess many advantages, including APC recruitment, pattern recognition receptor (PRR) activation, inflammasome activation, activation of MHC-presenting pathway and most important of all, T cell activation. Genetically-engineered Leishmania that can be inactivated by light exposure acts as a safe carrier to deliver specific antigens to APCs for activation of T cells and B cell stimulation. Based on this concept, we established a new model system to generate antigen-specific Leishmania adjuvant-- Leijuvant. We further designed a user-friendly MHC peptide prediction software to integrate key protein information and optimize the presentation of antigen peptides by MHC molecules. Our ultimate goal is to introduce Leijuvant as an effective, safe, and antigen-specific adjuvant to the vaccine industry and the general public.
 +
</div>
 +
<br><br>
 +
</div>
  
 +
<div class="mid2" style="background-color:#d0d0d0;top:130%;">
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<div style="font-size:60px;color:#140731;margin-left:35%;margin-top:2%;">
 +
<br>
 +
Start the Journey
 +
</div>
 +
<br></br>
 +
<br></br>
 +
<a href="https://2016.igem.org/Team:CGU_Taiwan/Description"><img style="border-radius:50%;border:10px solid #140731;padding:5px;width:20%;height:25%;position:absolute;margin-left:10%;" src="https://static.igem.org/mediawiki/2016/4/40/CGU_Taiwan--t4.jpg">
 +
<h2 style="font-size:35px;color:#140731;position:absolute;left:15%;top:490px;z-index:+1;text-decoration:none;">PROJECT</h2></a>
 +
<a href="http://facebook.com/igemcgu"><img style="border-radius:50%;border:10px solid #140731;padding:5px;width:20%;height:25%;position:absolute;margin-left:38%;" src="https://static.igem.org/mediawiki/2016/c/cd/CGU_Taiwan--macrophage.jpg">
 +
<h3 style="font-size:35px;color:#140731;position:absolute;left:45%;top:490px;text-decoration:none;">NEWS</h3></a>
 +
<a href="https://2016.igem.org/Team:CGU_Taiwan/Results"><img style="border-radius:50%;border:10px solid #140731;padding:5px;width:20%;height:25%;position:absolute;margin-left:66%;" src="https://static.igem.org/mediawiki/2016/7/7c/CGU_Taiwan--HA.jpg">
 +
<h4 style="font-size:35px;color:#140731;position:absolute;left:72%;top:490px;text-decoration:none;">RESULTS</h4></a>
 +
</div>
  
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<div class="column half_size" >
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<div class="end" style="top:190%;">
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<h5> Editing your wiki </h5>
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<div style="font-size:20px;color:white;text-decoration:none;margin-left:20%;margin-top:5%;">
−
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
+
Chang Gung University
−
<p> <a href="https://2016.igem.org/wiki/index.php?title=Team:Example&action=edit"> Click here to edit this page! </a></p>
+
</div>
 +
<br>
 +
<div style="color:white;font-size:15px;margin-left:10%;text-align:justify;">
 +
No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan (R.O.C.)
 +
<br>
 +
TEL: +886-3-2118800 FAX:+886-3-2118700
 +
<img src="https://static.igem.org/mediawiki/2016/e/eb/CGU_Taiwan--sponsor0.6.jpg" style="position:absolute;top:0%;margin-left:25%;width:35%;height:45%;margin-top:3%;">
 +
</div>
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</div>
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<br><br><br><br><br>
  
 +
<div class="end2" style="top:210%;">
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<br>
 +
<ul class="list3" class="margin-left:1%;margin-top:2%;">
 +
<li><a href="#anchor1"><b style="color:white;font-size:28px;margin-left:7%;">TOP</a></li>
 +
</ul>
 +
<br>
 +
<div class="sitemap" style="margin-left:5%;">
 +
<br>
 +
<b style="color:white;font-size:28px;margin-top:5%;margin-left:4%;text-decoration:none;">SITE MAP</b><br>
 +
<br><br>
 +
<img style="background-color:#0D014D;margin-left:20%;border-radius:50%;border:6px solid white;padding:5px;width:50%;height:90%;position:absolute;margin-left:2%;" src="https://static.igem.org/mediawiki/2016/0/03/CGU_Taiwan--leishmania3.jpg">
 
</div>
 
</div>
  
−
 
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<div class="sitemap" style="margin-left:22%;margin-top:-1%;">
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<div class="column half_size" >
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<ul class="list" class="margin-left:5%;">
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<h5>Tips</h5>
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<li><a href="https://2016.igem.org/Team:CGU_Taiwan"><b style="color:white;font-size:18px;margin-left:20%;">HOME</li></a>
−
<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Achievements"><b style="color:white;font-size:18px;margin-left:20%;">ACHIEVEMENTS</li></a>
−
<ul>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Interlab"><b style="color:white;font-size:18px;margin-left:20%;">INTERLAB</li></a>
−
<li>State your accomplishments! Tell people what you have achieved from the start. </li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Safety"><b style="color:white;font-size:18px;margin-left:20%;">SAFETY</li></a>
−
<li>Be clear about what you are doing and how you plan to do this.</li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Parts"><b style="color:white;font-size:18px;margin-left:20%;">PARTS</li></a>
−
<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
+
</ul>
−
<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
+
−
<li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li>
+
−
<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2016.igem.org/Calendar">iGEM 2016 calendar</a> </li>
+
−
<li>Have lots of fun! </li>
+
−
</ul>  
+
 
</div>
 
</div>
  
−
 
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<div class="sitemap" style="margin-left:40%;margin-top:-2%;">
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<div class="column half_size" >
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<ul class="list" class="margin-left:5%;">
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<h5>Inspiration</h5>
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<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Description"><b style="color:white;font-size:18px;margin-left:20%;">PROJECT</li></a>
−
<p> You can also view other team wikis for inspiration! Here are some examples:</p>
+
<br><br>
−
<ul>
+
<ul class="list2" class="margin-left:6%;margin-top:50%;">
−
<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Design"><b style="color:white;font-size:17px;margin-left:10%;">Design</li></a>
−
<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Background"><b style="color:white;font-size:17px;margin-left:10%;">Background</li></a>
−
<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Results"><b style="color:white;font-size:17px;margin-left:10%;">Results</li></a>
−
<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Proof"><b style="color:white;font-size:17px;margin-left:10%;">Proof</li></a>
−
<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Notebook"><b style="color:white;font-size:17px;margin-left:10%;">Notebook</li></a>
−
<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
+
<br><br>
 +
</ul>
 
</ul>
 
</ul>
 
</div>
 
</div>
  
−
<div class="column half_size" >
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<div class="sitemap" style="margin-left:55%;margin-top:-3.5%;">
−
<h5> Uploading pictures and files </h5>
+
<ul class="list" class="margin-left:5%;">
−
<p> You can upload your pictures and files to the iGEM 2016 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Human_Practices"><b style="color:white;font-size:18px;margin-left:20%;">HUMAN PRACTICES</li></a>
−
When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
+
<br><br>
−
 
+
<ul class="list2" class="margin-left:6%;margin-top:50%;">
−
 
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Human_Practices_Survey"><b style="color:white;font-size:17px;margin-left:10%;">Survey</li></a>
−
<div class="button_click" onClick=" parent.location= 'https://2016.igem.org/Special:Upload '">
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Human_Practices_Education"><b style="color:white;font-size:17px;margin-left:10%;">Education</li></a>
−
UPLOAD FILES
+
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Human_Practices_Communication"><b style="color:white;font-size:17px;margin-left:10%;">Communication</li></a>
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Entrepreneurship"><b style="color:white;font-size:17px;margin-left:10%;">Entrepreneurship</li></a>
 +
</ul>
 +
</ul>
 
</div>
 
</div>
  
 +
<div class="sitemap" style="margin-left:75%;margin-top:-3.5%;">
 +
<ul class="list" class="margin-left:5%;">
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Software"><b style="color:white;font-size:18px;margin-left:20%;">MODELING</li></a>
 +
<br><br>
 +
<ul class="list2" class="margin-left:6%;">
 +
<li><a href="http://163.25.92.36/igemcgu/igemwebhome.htm"><b style="color:white;font-size:17px;margin-left:10%;">McHug</li></a>
 +
</ul>
 +
</ul>
 +
<ul class="list" class="margin-left:1%;">
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Team"><b style="color:white;font-size:18px;margin-left:20%;">OUR TEAM</li></a>
 +
<br><br>
 +
<ul class="list2" class="margin-left:6%;margin-top:-5%;">
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Collaborations"><b style="color:white;font-size:17px;margin-left:10%;">Collaborations</li></a>
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Attributions"><b style="color:white;font-size:17px;margin-left:10%;">Attributions</li></a>
 +
<li><a href="https://2016.igem.org/Team:CGU_Taiwan/Team#anchor2"><b style="color:white;font-size:17px;margin-left:10%;">Sponsors</li></a>
 +
</ul>
 +
</ul>
 
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Latest revision as of 07:04, 2 December 2016

  • HOME
  • ACHIEVEMENTS
  • PROJECT
  • MODELING
  • HUMAN PRACTICES
  • PEOPLE
  • INTERLAB
  • SAFETY
  • PARTS














    • Abstract




    Leijuvant- A Revolutionary Choice of Vaccine Helper

    For many infectious diseases that still don’t have an effective vaccine, enhancing T cell immune response may be the key point to solve this problem. Leijuvant represents a whole new perspective of adjuvant that uses Leishmania as an effective T cell stimulator. Leishmania is a parasite that specifically lives within macrophage, a professional antigen presenting cell (APC). As a potential vaccine adjuvant, Leishmania possess many advantages, including APC recruitment, pattern recognition receptor (PRR) activation, inflammasome activation, activation of MHC-presenting pathway and most important of all, T cell activation. Genetically-engineered Leishmania that can be inactivated by light exposure acts as a safe carrier to deliver specific antigens to APCs for activation of T cells and B cell stimulation. Based on this concept, we established a new model system to generate antigen-specific Leishmania adjuvant-- Leijuvant. We further designed a user-friendly MHC peptide prediction software to integrate key protein information and optimize the presentation of antigen peptides by MHC molecules. Our ultimate goal is to introduce Leijuvant as an effective, safe, and antigen-specific adjuvant to the vaccine industry and the general public.



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    Chang Gung University

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