Team:Lubbock TTU/HP/Gold
Human Practices Gold
Our original idea for this project was to engineer a bacteria that we
could place within the wound beds of chronic wounds that would secrete therapeutic factors. After further conversations with professionals within the field, such as Dr. Kendra Rumbaugh, we decided to move away from actually placing bacteria within the wound because E. coli has a negative public connotation, and a probiotic would be a better option. E. coli can also cause a severe immune response. We decided as a team, that working in E. coli would be one of the easier model organism to work with as we are a first year iGEM team and had plenty to learn. Instead of designing bacteria to be placed inside a wound, we designed and built a bioreactor for our bacteria to grow and produce our therapeutic proteins for further isolation and purification. Dr. Kendra Rumbaugh’s expertise in the wound care field also helped us in braining storming our approach to creating a scaffold that mimics the wound matrix and guided us to appropriate articles about the subject.
Many thanks to the Rambaugh Lab!
