Difference between revisions of "Team:UESTC-software/Future"

 
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                 <li><a href="https://2016.igem.org/Team:UESTC-software/Project?id=0">PROJECT</a>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/Project?id=0">PROJECT</a>
 
                     <ul class="sub-nav">
 
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Description?id=0&index=0">Description</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Description">Description</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Design?id=0&index=1">Design</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Design">Design</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Features?id=0&index=2">Features</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Features">Features</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Model">Model</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Model">Modeling</a></li>
 
                          
 
                          
 
                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Proof">Proof</a></li>
 
                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Proof">Proof</a></li>
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                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Demonstrate">Result</a></li>
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                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Demonstrate">Results</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Future?id=0&index=5">Future</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Future">Future</a></li>
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                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Extra_work?id=0&index=7;">Extra Work—Bio2048</a></li>
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                        <li><a href="https://2016.igem.org/Team:UESTC-software/Parts">Parts</a></li>
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                         <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Extra_work">Extra Work—Bio2048</a></li>
 
                     </ul>
 
                     </ul>
 
                 </li>
 
                 </li>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/Judging?id=1">JUDGING</a>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/Judging?id=1">JUDGING</a>
 
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Medal_requirements?id=1&index=0">Medal Requirements</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Medal_requirements">Medal Requirements</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Safety?id=1&index=1">Safety</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Safety?">Safety</a></li>
 
                     </ul>
 
                     </ul>
 
                 </li>
 
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Members?id=2&index=0">Team</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Members?id=2&index=0">Team</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Collaborations">Collaborations</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Collaborations">Collaborations</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Notebooks?id=2&index=2">Notebooks</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Notebooks">Notebooks</a></li>
 
                     </ul>
 
                     </ul>
 
                 </li>
 
                 </li>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/HP">HUMAN PRACTICES</a>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/HP">HUMAN PRACTICES</a>
 
                     <ul class="sub-nav">
 
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                        <li><a href="https://2016.igem.org/Team:UESTC-software/HP/Gold">Gold</a></li>
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<li><a href="https://2016.igem.org/Team:UESTC-software/HP/Silver">Silver</a></li>                      
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                        <li><a href="https://2016.igem.org/Team:UESTC-software/HP/Silver">Silver</a></li>
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<li><a href="https://2016.igem.org/Team:UESTC-software/HP/Gold">Gold</a></li>
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                         <li><a href="https://2016.igem.org/Team:UESTC-software/Integrated_Practices">Integrated Practices</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Integrated_Practices">Integrated Practices</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Engagement">Engagement</a></li>
 
                         <li><a href="https://2016.igem.org/Team:UESTC-software/Engagement">Engagement</a></li>
 
                     </ul>
 
                     </ul>
 
                 </li>
 
                 </li>
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                 <li><a href="https://2016.igem.org/Team:UESTC-software/Document?id=3&index=0">DOCUMENT</a></li>
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                 <li><a href="https://2016.igem.org/Team:UESTC-software/Document">DOCUMENTS</a></li>
 
                  
 
                  
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/Attributions">ATTRIBUTIONS</a></li>
 
                 <li><a href="https://2016.igem.org/Team:UESTC-software/Attributions">ATTRIBUTIONS</a></li>
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</header>
 
</header>
 
<div class="content-top">
 
<div class="content-top">
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     <img src="https://static.igem.org/mediawiki/igem.org/4/41/Uestc_software-attributions.png">
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     <img src="https://static.igem.org/mediawiki/igem.org/1/15/Uestc_software-project_future2.png">
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     <p class="title">Attributions</p>
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     <p class="title">Future</p>
 
</div>
 
</div>
 
<div class="detail-content">
 
<div class="detail-content">
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                 <p>This summer, a team composed of fifteen members from UESTC, also from different hometowns, took part in the iGEM international competition. We gathered together to explore biological storage, to seek more accurate algorithms for simulating gene circuits, to optimize user interface more and more, again and again. During the process, every one made an effort. We also received a lot of help from other people, which encouraged us to create our best work, beyond this</p>
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                 <p> Although Bio101 has fulfilled its design goals to encode and decode information in DNA sequences, there is a long way to put DNA information storage into practical usage. In the future, we will focus on two aspects to improve our software further,<b> wet-lab validation</b> of our<b> DNA editing protocol</b> and<b> integration</b> of Bio101 with hardware for on-site DNA synthesis and sequencing.</p>
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                <h2 id="Member Attribution" style="text-align: center!important;">----------------------------Member Attributions----------------------------</h2>
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                 <h2 id="DNA Editing">DNA Editing </h2>
−
                <strong>Project</strong>
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                 <p>To prove the <b>feasibility</b> of data editing protocol, we plan to do a wet-lab validation. Bio101 provides a BioBrick part for the small-guide RNA (sgRNA) expression and we will test its efficiency and accuracy working together with <b>CRISPR/CAS9 system</b> to erase the DNA fragments which encoding the old data to be replace.</p>
−
                <br>
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                 <p class="img-p" ><img src="https://static.igem.org/mediawiki/2016/f/fd/UESTC-Software-future-1.png"style="font-size: 13px; width:80%; margin-left:20px;" /><br/><B>Fig.1.</B>Wet-lab validation of DNA editing.</p>
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                <strong style="font-style: italic;">Bio101 design</strong>
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                 <h2 id="System Integration">System Integration</h2>
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                <p class="one-line" style="margin-bottom:0;">Front-Web: Jianwei Xu, Jun Li, Meng Liu</p>
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                 <p>Currently, Bio101 provides a solution to the IT part of the DNA information storage system. For practical usage, we need to <b>integrate both the IT part and BT part</b>, including coding, synthesis, sequencing, decoding and editing, into one system. The latest development in the areas of DNA synthesis and sequencing and lab-on-chip provides us possibility. We will investigate some possible integration ideas in the future.  </p>
−
                <p class="one-line" style="margin:0;">Back-end and Webpage Framework: Dongkai Pu, Jianwei Xu</p>
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                 <p class="img-p" style="font-size: 13px;"><img src="https://static.igem.org/mediawiki/2016/7/7e/UESTC-Software-future-2.png"/><br/><B>Fig.2.</B>Integration of DNA information storage system. </p>
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                <p class="one-line" style="margin:0;">Modeling: Dongkai Pu, Meng Liu, Chenxiang Zheng, Hao Xu, Wei Zhao</p>
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−
                <p class="one-line" style="margin:0;">Testing and validation: Zhongtian Ma, Jianwei Xu</p>  
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                 <p class="one-line" style="margin:0;">Art Design: Xin Ma, Zining Wu</p>
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−
                 <p class="one-line" style="margin:0;">Documentation: Meng Liu, Jun Li, Yuening Yan, Caixi Xi</p>
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−
                <strong style="font-style: italic;">Bio2048 design</strong>
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−
                <p class="one-line" style="margin-bottom:0;">User Interface: Xin Ma</p>
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                <p class="one-line" style="margin:0;">Programming: Xin Ma</p>
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                <p class="one-line" style="margin:0;">Icon Degisn：Haobo Zhou</p>
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                <p class="one-line" style="margin:0;">Hierarchical Conception: Zhongtian Ma</p>
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                <strong>Human Practices and Collaborations</strong>
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                <br>
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                <strong style="font-style: italic;">Development of Data-Processing Tool for UESTC-China</strong>
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                <p class="one-line" style="margin-bottom:0;">Programming and Documentation: Jianwei Xu, Dongkai Pu, Xin Ma</p>
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                <strong style="font-style: italic;">Support for TMMU_China</strong>
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                <p class="one-line" style="margin-bottom:0;">Programming and Documentation: Meng Liu</p>
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                <strong style="font-style: italic;">Collaboration with AHUT_ China</strong>
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                <p class="one-line" style="margin-bottom:0;">Video meeting: Jianwei Xu, Hao Xu</p>
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                <strong style="font-style: italic;">iGEM Southwest China Union Meetup</strong>
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                <p class="one-line" style="margin-bottom:0;">Presentation: Chenxiang Zheng</p>
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                 <p class="one-line" style="margin:0;">Poster: Zining Wu</p>
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                <p class="one-line" style="margin:0;">Brief Introduction: Hui Che</p>
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                <strong style="font-style: italic;">Meet-up with TMMU_China and NJY-China</strong>
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                <p class="one-line" style="margin-bottom:0;">Presentation: Hui Che, Haobo Zhou</p>
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                <p class="one-line" style="margin:0;">Poster: Zining Wu</p>
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                <p class="one-line" style="margin:0;">Brief Introduction: Jianwei Xu</p>
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                <strong style="font-style: italic;">Science Lecture</strong>
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                <p class="one-line" style="margin-bottom:0;">Material Prepare: Caixi Xi, Hao Xu</p>
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                <p class="one-line" style="margin:0;">Presentation: Yuening Yan, Hui Che</p>
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                <p class="one-line" style="margin:0;">PPT Design: Zining Wu</p>
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                <p class="one-line" style="margin:0;">Photo: Haobo Zhou</p>
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                <p class="one-line" style="margin:0;">Documentation: Yuening Yan, Hui Che</p>
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                <strong>Lab-open day</strong>
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                <br>
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                <p class="one-line" style="margin-bottom:0;">Design and Plan: Hao Xu, Caixi Xi</p>
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                <strong style="font-style: italic;">Team’s microblog public platform</strong>
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                <p class="one-line" style="margin-bottom:0;">Management: Zhongtian Ma</p>
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                <strong style="font-style: italic;">Community propaganda</strong>
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                <p class="one-line" style="margin-bottom:0;">Design and Plan: Caixi Xi, Haobo Zhou</p>  
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                 <h2 id="Special Thanks to" style="text-align: center!important;">--------------------------------------Special Thanks to--------------------------------------</h2>
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                <strong>Professor Xianlong Wang, our primary PI</strong>
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−
               
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                 <p>For helping the UESTC-Software team design and plan our project. His guidance to all 15 members is greatly appreciated. </p>
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−
 
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                <strong>Ling Quan,our instructor</strong>
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−
 
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                <p>For her leadership and teaching us how to build a team. She taught us how to become more friendly and united. Also, she gave us advice on travel to Boston and the contents of our presentation.</p>
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−
 
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                <strong>Kaiyue Zhang, the team leader of 2015 UESTC-China, and Yaocong Duan, the team leader of 2015 UESTC-Software.</strong>
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                <p>For giving us advice on building our team and disciplines, providing support to us outside of training, which encouraged us to perfect our project.</p>
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−
 
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                <strong>Xu Wang, system administrator in Xingchen studio</strong>
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                <p>For building the server and helping us set up backstage when we had problem during visualization design.</p>
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−
 
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                <strong>Bohan Li, Ziyun Guan, Jingyi Wang, Huanghao Yang, Wei Liu, the Preliminary Team Members (sophomores of UESTC).</strong>
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                <p>For helping us with human practice including the implementation of the visiting activity “To Be Scientists Tomorrow” and Community Advocacy. Their help is especially appreciated for taking photos, shooting videos and preparing materials. </p>
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−
 
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                <strong>Other teams taking part in the competition</strong>
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−
                 <br>
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                <a href="https://2016.igem.org/Team:SCU-China" style="color:#3C9CD3;text-indent:28px;font-size:15px;" target="_blank">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>·Sichuan University</b></a>
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−
                <br><br>
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                <a href="https://2016.igem.org/Team:Nanjing-China" style="color:#3C9CD3;text-indent:28px;font-size:15px;" target="_blank">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>·Nanjing University</b></a>
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                <br><br>
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                <a href="https://2016.igem.org/Team:TMMU_China" style="color:#3C9CD3;text-indent:28px;font-size:15px;" target="_blank">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>·Third Military Medical University</b></a>
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−
                <br><br>
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−
                <a href="http://www.sicau.com" style="color:#3C9CD3;text-indent:28px;font-size:15px;" target="_blank">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>·Sichuan Agricultural University</b></a>
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−
                <br><br>
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−
                <a href="https://2016.igem.org/Team:UESTC-China" style="color:#3C9CD3;text-indent:28px;font-size:15px;" target="_blank">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <b>·Experiment team from UESTC</b></a>
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−
                <p>For discussing our projects with us and putting forward some views and suggestions to improve our task. </p>
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−
                <strong>The Developers of Following Libraries</strong>
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                <br>
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                <p><a href="https://github.com/wout/svg.js" style="color:#3C9CD3;" target="_blank">wout/svg.js:</a>A lightweight library for manipulating and animating <a href="https://github.com/jquery/jquery" style="color:#3C9CD3;" target="_blank">SVG
+
−
                jquery/jquery:</a>jQuery JavaScript Library.
+
−
                </p>
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                <p>For the former making our work in generating SVG images more convenient, and help us encapsulate DOM and AJAX operation, as well as simplify grammar.</p>
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−
 
+
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                <strong>Dean’s Office of University of Electronic Science and Technology of China</strong>
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−
                <p>It’s a great deal for us that the Dean’s Office provided our funds during the competition. The Dean’s Office covered the flight fees, accommodation, also Team Registration Fees and the Jamboree Attendance Fee, which greatly reduced our financial burden and motivated us to focus on the competition.</p>
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−
 
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                <strong>Thanks again to all people involved for helping us be a more successful iGEM team. This summer, because of your support, we can better ourselves.</strong>
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                <br>
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                <br>
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                <img src="https://static.igem.org/mediawiki/2016/7/7d/Uestc_software-mingxie1.PNG" style="width:70%;margin-left:140px;"></img>
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</div>
 
</div>
 
<footer class="footer">
 
<footer class="footer">
 
     <div class="footer-top">
 
     <div class="footer-top">
 
         <p>FOLLOW US：
 
         <p>FOLLOW US：
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             <a href="https://github.com/IGEM-UESTC-software" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/0/06/Uestc_software-github.png" /></a>
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             <a href="https://github.com/igemsoftware2016/UESTC-Software-2016" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/0/06/Uestc_software-github.png" /></a>
 
             <a href="http://www.uestc.edu.cn/" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/a/a4/Uestc_software-school.png" /></a>
 
             <a href="http://www.uestc.edu.cn/" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/a/a4/Uestc_software-school.png" /></a>
 
             <a href="http://weibo.com/u/5621240588?refer_flag=1001030101_&is_hot=1" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/b/b1/Uestc_software-weibo.png" /></a>
 
             <a href="http://weibo.com/u/5621240588?refer_flag=1001030101_&is_hot=1" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/b/b1/Uestc_software-weibo.png" /></a>
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             <a href="#Member Attribution">
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             <a href="#DNA Editing ">
 
                 <span></span>
 
                 <span></span>
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               Member Attribution
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               DNA Editing
 
             </a>
 
             </a>
 
         </li>
 
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         <li>
 
         <li>
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             <a href="#Special Thanks to">
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             <a href="#System Integration">
 
                 <span></span>
 
                 <span></span>
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              Special Thanks to
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            System Integration
 
             </a>
 
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Latest revision as of 01:42, 20 October 2016

三级页面

Future

Although Bio101 has fulfilled its design goals to encode and decode information in DNA sequences, there is a long way to put DNA information storage into practical usage. In the future, we will focus on two aspects to improve our software further, wet-lab validation of our DNA editing protocol and integration of Bio101 with hardware for on-site DNA synthesis and sequencing.

DNA Editing

To prove the feasibility of data editing protocol, we plan to do a wet-lab validation. Bio101 provides a BioBrick part for the small-guide RNA (sgRNA) expression and we will test its efficiency and accuracy working together with CRISPR/CAS9 system to erase the DNA fragments which encoding the old data to be replace.


Fig.1.Wet-lab validation of DNA editing.

System Integration

Currently, Bio101 provides a solution to the IT part of the DNA information storage system. For practical usage, we need to integrate both the IT part and BT part, including coding, synthesis, sequencing, decoding and editing, into one system. The latest development in the areas of DNA synthesis and sequencing and lab-on-chip provides us possibility. We will investigate some possible integration ideas in the future.


Fig.2.Integration of DNA information storage system.

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