Difference between revisions of "Team:UESTC-software/Future"
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<li><a href="https://2016.igem.org/Team:UESTC-software/Description">Description</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Description">Description</a></li> | ||
<li><a href="https://2016.igem.org/Team:UESTC-software/Design">Design</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Design">Design</a></li> | ||
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Features"> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Features">Features</a></li> |
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Model"> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Model">Modeling</a></li> |
<li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Proof">Proof</a></li> | <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Proof">Proof</a></li> | ||
<li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Demonstrate">Results</a></li> | <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Demonstrate">Results</a></li> | ||
<li><a href="https://2016.igem.org/Team:UESTC-software/Future">Future</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Future">Future</a></li> | ||
| + | <li><a href="https://2016.igem.org/Team:UESTC-software/Parts">Parts</a></li> | ||
<li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Extra_work">Extra Work—Bio2048</a></li> | <li class="three-nav"><a href="https://2016.igem.org/Team:UESTC-software/Extra_work">Extra Work—Bio2048</a></li> | ||
</ul> | </ul> | ||
</li> | </li> | ||
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Judging">JUDGING</a> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Judging?id=1">JUDGING</a> |
<ul class="sub-nav"> | <ul class="sub-nav"> | ||
<li><a href="https://2016.igem.org/Team:UESTC-software/Medal_requirements">Medal Requirements</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Medal_requirements">Medal Requirements</a></li> | ||
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Safety">Safety</a></li> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Safety?">Safety</a></li> |
</ul> | </ul> | ||
</li> | </li> | ||
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Team">TEAM</a> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Team?id=2">TEAM</a> |
<ul class="sub-nav"> | <ul class="sub-nav"> | ||
| − | <li><a href="https://2016.igem.org/Team:UESTC-software/Members">Team</a></li> | + | <li><a href="https://2016.igem.org/Team:UESTC-software/Members?id=2&index=0">Team</a></li> |
<li><a href="https://2016.igem.org/Team:UESTC-software/Collaborations">Collaborations</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Collaborations">Collaborations</a></li> | ||
<li><a href="https://2016.igem.org/Team:UESTC-software/Notebooks">Notebooks</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Notebooks">Notebooks</a></li> | ||
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<li><a href="https://2016.igem.org/Team:UESTC-software/HP">HUMAN PRACTICES</a> | <li><a href="https://2016.igem.org/Team:UESTC-software/HP">HUMAN PRACTICES</a> | ||
<ul class="sub-nav"> | <ul class="sub-nav"> | ||
| − | + | <li><a href="https://2016.igem.org/Team:UESTC-software/HP/Silver">Silver</a></li> | |
| − | + | <li><a href="https://2016.igem.org/Team:UESTC-software/HP/Gold">Gold</a></li> | |
| + | |||
<li><a href="https://2016.igem.org/Team:UESTC-software/Integrated_Practices">Integrated Practices</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Integrated_Practices">Integrated Practices</a></li> | ||
<li><a href="https://2016.igem.org/Team:UESTC-software/Engagement">Engagement</a></li> | <li><a href="https://2016.igem.org/Team:UESTC-software/Engagement">Engagement</a></li> | ||
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</header> | </header> | ||
<div class="content-top"> | <div class="content-top"> | ||
| − | <img src="https://static.igem.org/mediawiki/igem.org/1/15/Uestc_software- | + | <img src="https://static.igem.org/mediawiki/igem.org/1/15/Uestc_software-project_future2.png"> |
<p class="title">Future</p> | <p class="title">Future</p> | ||
</div> | </div> | ||
<div class="detail-content"> | <div class="detail-content"> | ||
| − | <p> Although Bio101 has fulfilled its design goals to encode and decode information in DNA sequences, there is a long way to put DNA information storage into practical usage. In the future, we will focus on two aspects to improve our software further, wet-lab | + | <p> Although Bio101 has fulfilled its design goals to encode and decode information in DNA sequences, there is a long way to put DNA information storage into practical usage. In the future, we will focus on two aspects to improve our software further,<b> wet-lab validation</b> of our<b> DNA editing protocol</b> and<b> integration</b> of Bio101 with hardware for on-site DNA synthesis and sequencing.</p> |
<h2 id="DNA Editing">DNA Editing </h2> | <h2 id="DNA Editing">DNA Editing </h2> | ||
| − | <p>To prove the feasibility of data editing protocol, we plan to do a wet-lab validation. | + | <p>To prove the <b>feasibility</b> of data editing protocol, we plan to do a wet-lab validation. Bio101 provides a BioBrick part for the small-guide RNA (sgRNA) expression and we will test its efficiency and accuracy working together with <b>CRISPR/CAS9 system</b> to erase the DNA fragments which encoding the old data to be replace.</p> |
| − | <p class="img-p | + | <p class="img-p" ><img src="https://static.igem.org/mediawiki/2016/f/fd/UESTC-Software-future-1.png"style="font-size: 13px; width:80%; margin-left:20px;" /><br/><B>Fig.1.</B>Wet-lab validation of DNA editing.</p> |
<h2 id="System Integration">System Integration</h2> | <h2 id="System Integration">System Integration</h2> | ||
| − | <p>Currently, Bio101 provides a solution to the IT part of the DNA information storage system. For practical usage, we need to integrate both the IT part and BT part, including coding, synthesis, sequencing, decoding and editing, into one system. The latest development | + | <p>Currently, Bio101 provides a solution to the IT part of the DNA information storage system. For practical usage, we need to <b>integrate both the IT part and BT part</b>, including coding, synthesis, sequencing, decoding and editing, into one system. The latest development in the areas of DNA synthesis and sequencing and lab-on-chip provides us possibility. We will investigate some possible integration ideas in the future. </p> |
<p class="img-p" style="font-size: 13px;"><img src="https://static.igem.org/mediawiki/2016/7/7e/UESTC-Software-future-2.png"/><br/><B>Fig.2.</B>Integration of DNA information storage system. </p> | <p class="img-p" style="font-size: 13px;"><img src="https://static.igem.org/mediawiki/2016/7/7e/UESTC-Software-future-2.png"/><br/><B>Fig.2.</B>Integration of DNA information storage system. </p> | ||
</div> | </div> | ||
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<div class="footer-top"> | <div class="footer-top"> | ||
<p>FOLLOW US： | <p>FOLLOW US： | ||
| − | <a href="https://github.com/ | + | <a href="https://github.com/igemsoftware2016/UESTC-Software-2016" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/0/06/Uestc_software-github.png" /></a> |
<a href="http://www.uestc.edu.cn/" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/a/a4/Uestc_software-school.png" /></a> | <a href="http://www.uestc.edu.cn/" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/a/a4/Uestc_software-school.png" /></a> | ||
<a href="http://weibo.com/u/5621240588?refer_flag=1001030101_&is_hot=1" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/b/b1/Uestc_software-weibo.png" /></a> | <a href="http://weibo.com/u/5621240588?refer_flag=1001030101_&is_hot=1" target="_blank"><img src="https://static.igem.org/mediawiki/igem.org/b/b1/Uestc_software-weibo.png" /></a> | ||
Latest revision as of 01:42, 20 October 2016
Future
Although Bio101 has fulfilled its design goals to encode and decode information in DNA sequences, there is a long way to put DNA information storage into practical usage. In the future, we will focus on two aspects to improve our software further, wet-lab validation of our DNA editing protocol and integration of Bio101 with hardware for on-site DNA synthesis and sequencing.
DNA Editing
To prove the feasibility of data editing protocol, we plan to do a wet-lab validation. Bio101 provides a BioBrick part for the small-guide RNA (sgRNA) expression and we will test its efficiency and accuracy working together with CRISPR/CAS9 system to erase the DNA fragments which encoding the old data to be replace.
Fig.1.Wet-lab validation of DNA editing.
System Integration
Currently, Bio101 provides a solution to the IT part of the DNA information storage system. For practical usage, we need to integrate both the IT part and BT part, including coding, synthesis, sequencing, decoding and editing, into one system. The latest development in the areas of DNA synthesis and sequencing and lab-on-chip provides us possibility. We will investigate some possible integration ideas in the future.
Fig.2.Integration of DNA information storage system.
CATALOGUE
CATALOGUE