Difference between revisions of "Team:Cambridge-JIC/Motivation"

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     <p style="font-family:Open Sans; font-size:150%; text-align:center;">Various proteins have already been successfully expressed in chloroplasts, including:</p>
 
     <p style="font-family:Open Sans; font-size:150%; text-align:center;">Various proteins have already been successfully expressed in chloroplasts, including:</p>
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    <p style="font-family:Arvo; font-size: 150%; text-align:right">Transgene expression in microalgae can total up to 30-50% of a cell’s dry biomass, as unlike in higher plants and mammals, metabolic energy in microalgae is not directed towards maintaining complex differentiated structures.</p>
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Revision as of 17:06, 18 October 2016

Cambridge-JIC

OUR MOTIVATION...

I. Microalgal chlroplasts as an alternative expression system

Chloroplasts hold a massive potential as an alternative protein expression system, due to their outstanding expression yields, diversity of post-translational modifications and auto/mixotrophic lifestyles of plants and microalgae.

Various proteins have already been successfully expressed in chloroplasts, including:

  • monoclonal antibodies
  • antigens
  • anti-toxins
  • growth factors

Transgene expression in microalgae can total up to 30-50% of a cell’s dry biomass, as unlike in higher plants and mammals, metabolic energy in microalgae is not directed towards maintaining complex differentiated structures.

I. Microalgal chlroplasts as an alternative expression system

I. Microalgal chlroplasts as an alternative expression system