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Revision as of 17:09, 18 October 2016
![](http://images.clipartpanda.com/gear-clipart-9T4eppGbc.png)
OUR MOTIVATION...
I. Microalgal chlroplasts as an alternative expression system
Chloroplasts hold a massive potential as an alternative protein expression system, due to their outstanding expression yields, diversity of post-translational modifications and auto/mixotrophic lifestyles of plants and microalgae.
![](https://static.igem.org/mediawiki/2016/8/8c/T--Cambridge-JIC--motivation--table1.jpg)
Various proteins have already been successfully expressed in chloroplasts, including:
- monoclonal antibodies
- antigens
- anti-toxins
- growth factors
Transgene expression in microalgae can total up to 30-50% of a cell’s dry biomass, as unlike in higher plants and mammals, metabolic energy in microalgae is not directed towards maintaining complex differentiated structures.
II. Microalgae chloroplasts as a model for higher plants
I. Microalgal chlroplasts as an alternative expression system