Difference between revisions of "Team:UCLA/Part Collection"
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<h6 align="center">Our parts collection features a small library of synthetic protein cages PC Quad 3.0 (obtained from the Yeates Lab) and O3-33 (obtained from the Baker Lab) and their various mutants. These mutants contain insertion mutations that produce a thrombin cleavage site on the exterior of the cage. In the presence of thrombin protease, these mutants are cleaved at the thrombin cleavage site, inducing disassembly of the cage and theoretically releasing an encapsulated molecule. | <h6 align="center">Our parts collection features a small library of synthetic protein cages PC Quad 3.0 (obtained from the Yeates Lab) and O3-33 (obtained from the Baker Lab) and their various mutants. These mutants contain insertion mutations that produce a thrombin cleavage site on the exterior of the cage. In the presence of thrombin protease, these mutants are cleaved at the thrombin cleavage site, inducing disassembly of the cage and theoretically releasing an encapsulated molecule. | ||
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Revision as of 18:08, 17 October 2016
Best Parts Collection
Our parts collection features a small library of synthetic protein cages PC Quad 3.0 (obtained from the Yeates Lab) and O3-33 (obtained from the Baker Lab) and their various mutants. These mutants contain insertion mutations that produce a thrombin cleavage site on the exterior of the cage. In the presence of thrombin protease, these mutants are cleaved at the thrombin cleavage site, inducing disassembly of the cage and theoretically releasing an encapsulated molecule.
| Name | Type | Description | Length |
|---|---|---|---|
| BBa_K2068000 | Generator | PCQuad 3.0 Wildtype | 1368 |
| BBa_K2068001 | Generator | PCQuad 3.0 Mutant 1 | 1389 |
| BBa_K2068002 | Generator | PCQuad 3.0 Mutant 2 | 1389 |
| BBa_K2068003 | Generator | PCQuad 3.0 Mutant 4 | 1389 |
| BBa_K2068004 | Generator | PCQuad 3.0 Mutant 13 | 1383 |
| BBa_K2068005 | Generator | O3-33 Wild Type | 576 |
| BBa_K2068006 | Generator | O3-33 Mutant aa88 | 597 |
| BBa_K2068007 | Generator | O3-33 Mutant aa118 | 597 |
| BBa_K2068008 | Generator | O3-33 Mutant aa173 | 603 |
