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<br> Views below were collected from three iGEM team members in the past. We truly appreciate their | <br> Views below were collected from three iGEM team members in the past. We truly appreciate their | ||
<br> insightful input. | <br> insightful input. | ||
− | |||
<br> | <br> | ||
<br>"Detrimental gene mutation leading to cancer has been a problem that perplex human for a long time, | <br>"Detrimental gene mutation leading to cancer has been a problem that perplex human for a long time, | ||
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<br> together and solve them together, which made the whole team grow together. I wish you a good luck, iGEM | <br> together and solve them together, which made the whole team grow together. I wish you a good luck, iGEM | ||
<br> 2016 Tsinghua team!", Xiong Sihan. | <br> 2016 Tsinghua team!", Xiong Sihan. | ||
+ | <br> | ||
+ | <br>"Finding ways to surveil and respond to genetic mutations is one of the most pivotal mission for all living | ||
+ | <br> creatures along the river of evolution, also for scientists today, who have been sparing no effort in | ||
+ | <br> seeking ways to prevent and treat cancer. In addressing this challenging question, Tsinghua Team raised a | ||
+ | <br> pioneering idea of using a RNA-targeting CRISPR/Cas9 system to detect critical genetic mutations and induce | ||
+ | <br> the suicide of the mutated cells. Creating Cas9 protein with GAL4 binding ability and precise discrimination | ||
+ | <br> of normal and mutated genes are two highlights of the project. Delicate control of the whole system is | ||
+ | <br> never easy, however, Tsinghua Team has successfully proved the concept in baking yeast. The next goal may | ||
+ | <br> be mammalian systems. From my perspectives, techniques like the suvCas9 have great potential in next | ||
+ | <br> generation of cancer therapy because they could work together with the hosts’ immune system to prevent | ||
+ | <br> malignancy at the first line.", Liu Yue. | ||
+ | <br> | ||
+ | <br>"Congratulations that you have done a really cool job! I am fascinated by what you have brought to the iGEM | ||
+ | <br> society. Surveillance is a rather important idea, that you're treating a cellular system, or your genetic | ||
+ | <br> machine, less like a pool of interactions but more like a sophisticated and well-functioning system, with | ||
+ | <br> top-down self regulation. This, I believe, will be one of the foundations for future genetic machines, and | ||
+ | <br> your delecate work will provide huge help for future iGEMers and researchers. Look so much forward to your | ||
+ | <br> presentation this year!", Wang Jiawei | ||
+ | <br> | ||
+ | <br> | ||
+ | |||
</div> | </div> | ||
</div> | </div> |
Revision as of 01:59, 20 October 2016