Difference between revisions of "Team:NUDT CHINA"
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<meta name="HandheldFriendly" content="True" /> | <meta name="HandheldFriendly" content="True" /> | ||
<meta name="MobileOptimized" content="320" /> | <meta name="MobileOptimized" content="320" /> | ||
| − | + | <meta name="viewport" content="width=device-width, initial-scale=1.0" /> | |
<meta content="on" http-equiv="cleartype" /> | <meta content="on" http-equiv="cleartype" /> | ||
<meta property="og:title" content="Home" /> | <meta property="og:title" content="Home" /> | ||
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<a class="nav-global__link" title="" href="#">AWARDS</a></li> | <a class="nav-global__link" title="" href="#">AWARDS</a></li> | ||
</ul> | </ul> | ||
| − | <style> | + | <style>#menu06{width:200px;right:0px;} #menu07{width:200px;right:0px;} |
| − | + | ||
| − | + | ||
| − | + | ||
| − | #menu06{width:200px;right:0px;} #menu07{width:200px;right:0px;} | + | |
#menu01 .arrow-up{margin-right:6.429rem;} | #menu01 .arrow-up{margin-right:6.429rem;} | ||
#menu02 .arrow-up{margin-right:90px;} #menu03 .arrow-up{margin-right:90px;} #menu06 .arrow-up{margin-right:120px;} #menu07 .arrow-up{margin-right:27px;} #menu01{width:200px;right:31rem;} #menu02{width:200px;right:27rem;} #menu03{width:200px;right:21.3rem;} | #menu02 .arrow-up{margin-right:90px;} #menu03 .arrow-up{margin-right:90px;} #menu06 .arrow-up{margin-right:120px;} #menu07 .arrow-up{margin-right:27px;} #menu01{width:200px;right:31rem;} #menu02{width:200px;right:27rem;} #menu03{width:200px;right:21.3rem;} | ||
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</nav> | </nav> | ||
<style>.nav-global ul li a{ font-size:0.85rem; } @media screen and (max-width: 865px) { .nav-global ul li a{ font-size:0.85rem; } } | <style>.nav-global ul li a{ font-size:0.85rem; } @media screen and (max-width: 865px) { .nav-global ul li a{ font-size:0.85rem; } } | ||
| − | + | ||
| + | |||
#feature{ | #feature{ | ||
background-size:100%; | background-size:100%; | ||
} | } | ||
| − | @media screen and (max-width: | + | @media screen and (max-width: 1280px) { |
#feature{ | #feature{ | ||
| − | background-size: | + | background-size:1280px; |
} | } | ||
| − | } | + | } |
</style> | </style> | ||
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<!-- end .row --></div> | <!-- end .row --></div> | ||
<!-- end #header-outer-wrap--> | <!-- end #header-outer-wrap--> | ||
| − | <div id="feature" class="row collapse text-light feature-footer-active" style="background-color: rgb(3,13,38);background-image:url(https://static.igem.org/mediawiki/2016/thumb/3/3f/NUDT_CHINA2016_FILES-img-banner-3.0.png/800px-NUDT_CHINA2016_FILES-img-banner-3.0.png) | + | <div id="feature" class="row collapse text-light feature-footer-active" style="background-color: rgb(3,13,38);background-image:url(https://static.igem.org/mediawiki/2016/thumb/3/3f/NUDT_CHINA2016_FILES-img-banner-3.0.png/800px-NUDT_CHINA2016_FILES-img-banner-3.0.png);background-repeat:no-repeat;"> |
<div class="inner-wrap medium-24 columns"> | <div class="inner-wrap medium-24 columns"> | ||
<!--TYPO3SEARCH_begin--> | <!--TYPO3SEARCH_begin--> | ||
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<div class="carousel " id="slideshow-4811" data-cycle-log="false" data-cycle-auto-height="calc" data-cycle-prev="#prev-4811" data-cycle-next="#next-4811" data-cycle-pager="#cycle-pager-4811" data-cycle-easing="easeInOutQuad" data-cycle-fx="scrollVertUp" data-cycle-center-horz="true" data-cycle-speed="1000" data-cycle-timeout="8000" data-cycle-paused="true" data-cycle-slides="> div.slide"> | <div class="carousel " id="slideshow-4811" data-cycle-log="false" data-cycle-auto-height="calc" data-cycle-prev="#prev-4811" data-cycle-next="#next-4811" data-cycle-pager="#cycle-pager-4811" data-cycle-easing="easeInOutQuad" data-cycle-fx="scrollVertUp" data-cycle-center-horz="true" data-cycle-speed="1000" data-cycle-timeout="8000" data-cycle-paused="true" data-cycle-slides="> div.slide"> | ||
<div class="slide first"> | <div class="slide first"> | ||
| − | <link rel="stylesheet" href="/Team | + | <link rel="stylesheet" href="/Team:NUDT_CHINA/CSS3?action=raw&ctype=text/css" /> |
<!-- Quick initialize with theme color from first slide --> | <!-- Quick initialize with theme color from first slide --> | ||
<div class="row collapse " id="c6601" data-theme-class="bh-color__theme-c6601"> | <div class="row collapse " id="c6601" data-theme-class="bh-color__theme-c6601"> | ||
<div class="columns"> | <div class="columns"> | ||
| − | <section class="big-header bh__height-size-3 text-light bh__video | + | <section class="big-header bh__height-size-3 text-light bh__video"> |
<div class="bh__background bh__background-color "></div> | <div class="bh__background bh__background-color "></div> | ||
| − | <div class="bh__content-wrap | + | <div class="bh__content-wrap"> |
<div class="bh__content "> | <div class="bh__content "> | ||
<div class="bh__content-inner-wrap"> | <div class="bh__content-inner-wrap"> | ||
<!--h3 class="bh__subtitle"><a href="http#/explore/whats-here/exhibits/brick-by-brick/"><span class="line-wrap"><span class="line"><span class="bh__info">Exhibit / </span>Brick by Brick</span></span></a></h3--> | <!--h3 class="bh__subtitle"><a href="http#/explore/whats-here/exhibits/brick-by-brick/"><span class="line-wrap"><span class="line"><span class="bh__info">Exhibit / </span>Brick by Brick</span></span></a></h3--> | ||
| + | <h1 class="bh__title "> | ||
| + | <!--<a href="#">--> | ||
| + | <span class="line-wrap"> | ||
| + | <span class="line">Cancer,</span></span> | ||
| + | <br> | ||
| + | <span style="line-height:75px;" class="line-wrap"> | ||
| + | <span style="line-height:75px;" class="line">No More Hiding</span></span> | ||
| + | <!--</a>--> | ||
| + | </h1> | ||
<h2 style="font-size:36px;" class="bh__title "> | <h2 style="font-size:36px;" class="bh__title "> | ||
<!--<a href="#">--> | <!--<a href="#">--> | ||
| − | + | <span style="line-height:41px;" class="line-wrap"> | |
| − | + | <span style="line-height:41px;" class="line">Development of A Novel</span></span> | |
| − | + | <span style="line-height:41px;" class="line-wrap"> | |
| − | + | <span style="line-height:41px;" class="line">Blood-MicroRNA Handy Detection System with CRISPR</span></span> | |
| − | <!--</a>--></h2> | + | <!--</a>--> |
| + | </h2> | ||
</div> | </div> | ||
</div> | </div> | ||
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<div class="cycle-pager" id="cycle-pager-4811"></div> | <div class="cycle-pager" id="cycle-pager-4811"></div> | ||
</div> | </div> | ||
| − | + | <!--TYPO3SEARCH_end--></div> | |
| − | + | <!-- end .columns --></div> | |
<!-- end #feature --> | <!-- end #feature --> | ||
<!-- end .columns --></div> | <!-- end .columns --></div> | ||
| − | <div style="margin-top: | + | <div style="margin-top:80px;" id="content-wrap-ink"><!-- adjust in add_JS --> |
| − | + | <div class="row footer-link" style=""> | |
| + | <div style="background-color:rgb(10,31,84);float:right;height:250px;width:38%;font-weight:bold;line-height:64px;color:white;font-size:36px;"> | ||
| + | <br/> | ||
| + | <div style="margin-left:30px;line-height:48px;">PROJECT | ||
| + | <br/> BRIEF <br/> DESCRIPTION</div></div> | ||
| + | <div style="margin-left:-10px;color:black;font-size:16px;font-size:18px;width:60%;"> | ||
| + | |||
| + | |||
| + | <div style=”text-indent:22pt;”> | ||
| + | <p><span style="margin-left:22pt; line-height:2;font-family:Perpetua;font-size:18px;">MicroRNAs (miRNA), serve as critical gene expression regulators at the transcriptional and post-transcriptional levels, have also been found as important blood-based biomarkers for early detection of cancers. However, their current in vitro detection methods are relatively complex, costly and low sensitive. Our project attempts to establish a novel in vitro miRNA detection system which is efficient, sensitive, specific, low-cost and output-visible. In this system, CRISPR-Cas9 technique is modified to integrate with split-HRP systems. The advanced chain-replacement and rolling circle amplification technologies are also involved and optimized. </span> </p > | ||
| + | </div> | ||
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| − | </div> | + | </div> |
| − | + | <div class="row footer-link" style=""> | |
| − | + | <div style=”text-indent:22pt;”> | |
| − | < | + | <p><span style="margin-left:22pt;line-height:2;font-family:Perpetua;font-size:18px;">To proof our concept and demonstrate our designs, miR let-7a, a typical lung cancer biomarker in serum, was selected as a detection prototype. As expected, gradient dilution miR let-7a showed significant signal variation both resolved in water and serum. The results were exceedingly in consistent with the modeling data, which obtained parameters from experiment results and theoretical calculation and in turn provided important experimental conditions for wet-lab. Finally, our approach was resorted to the clinical amplification by comparing the serum miR let-7a concentrations between non-small cell lung cancer (NSCLC) and healthy volunteers. Results confirmed the significant miR let-7a down-regulation in NSCLC, and demonstrated the clinical practicability of our detection system. </span> </p > |
| + | <p><span style="margin-left:22pt;line-height:2;font-family:Perpetua;font-size:18px;">Not only for the analyses of miRNA, this system may ideally be compatible for the detection of various series of small non-coding RNAs. To our knowledge, we are the first to use the CRISPR-Cas9 system as a small non-coding RNA monitor in vitro. Its establishment and further development might provide a new approach for rapid and low-cost cancer screening, virus detection and curative efficacy assessment. </span> </p > | ||
| + | </div> | ||
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<br/> | <br/> | ||
| − | + | <br/> | |
| − | + | <video style="width:100%;" controls="controls" preload="auto"> | |
| − | + | <source src="/wiki/images/2/26/T--NUDT_CHINA--OPEN-UP_MOVIE.MOV" type="video/mp4" /> | |
| − | + | Your browser does not support the video tag. Please click <a href="/wiki/images/2/26/T--NUDT_CHINA--OPEN-UP_MOVIE.MOV">HERE</a> to open this video! | |
| − | + | </video> | |
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| − | + | <br/></div> | |
</div> | </div> | ||
<!-- end #content-wrap --> | <!-- end #content-wrap --> | ||
<div style="border:solid 1px rgb(10,31,84);background-color:rgb(10,31,84);"> | <div style="border:solid 1px rgb(10,31,84);background-color:rgb(10,31,84);"> | ||
<div class="row footer-link" style="border:solid 0px red;margin-top:100px;"> | <div class="row footer-link" style="border:solid 0px red;margin-top:100px;"> | ||
| − | <style> | + | <style>.menu-link-container a{ color:white; font-size:14px;line-height:26px; } |
.menu-link-container a:hover{ | .menu-link-container a:hover{ | ||
text-decoration:underline; | text-decoration:underline; | ||
Latest revision as of 15:37, 3 November 2016
