(13 intermediate revisions by 5 users not shown) | |||
Line 306: | Line 306: | ||
<a href="https://2016.igem.org/Team:LambertGA/Team" class="dropbtn">Team</a> | <a href="https://2016.igem.org/Team:LambertGA/Team" class="dropbtn">Team</a> | ||
<div class="dropdown-content"> | <div class="dropdown-content"> | ||
+ | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Team">Team</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Collaborations">Collaborations</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Collaborations">Collaborations</a> | ||
</div> | </div> | ||
Line 316: | Line 317: | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Experiments">Experiments</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Experiments">Experiments</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Proof">Proof of Concept</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Proof">Proof of Concept</a> | ||
− | |||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Results">Results</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Results">Results</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Notebook">Notebook</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Notebook">Notebook</a> | ||
Line 324: | Line 324: | ||
<a href="https://2016.igem.org/Team:LambertGA/Parts" class="dropbtn">Parts</a> | <a href="https://2016.igem.org/Team:LambertGA/Parts" class="dropbtn">Parts</a> | ||
<div class="dropdown-content"> | <div class="dropdown-content"> | ||
+ | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Parts">Parts</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Basic_Part">Basic Parts</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Basic_Part">Basic Parts</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Composite_Part">Composite Parts</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Composite_Part">Composite Parts</a> | ||
Line 333: | Line 334: | ||
<a href="https://2016.igem.org/Team:LambertGA/Human_Practices" class="dropbtn">Human Practices</a> | <a href="https://2016.igem.org/Team:LambertGA/Human_Practices" class="dropbtn">Human Practices</a> | ||
<div class="dropdown-content"> | <div class="dropdown-content"> | ||
+ | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Human_Practices">Human Practices</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/HP/Silver">Silver</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/HP/Silver">Silver</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/HP/Gold">Gold</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/HP/Gold">Gold</a> | ||
<a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Integrated_Practices">Integrated Practices</a> | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Integrated_Practices">Integrated Practices</a> | ||
− | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Engagement"> | + | <a class="drplink" style="transition: color 0.5s ease-in-out;" href="https://2016.igem.org/Team:LambertGA/Engagement">Engagement</a> |
</div> | </div> | ||
</li><!-- | </li><!-- | ||
Line 377: | Line 379: | ||
<div class="img-left"> | <div class="img-left"> | ||
<table> | <table> | ||
− | <!--<img class="img-responsive" style="width: | + | <!--<img class="img-responsive" style="width:650px" src="https://static.igem.org/mediawiki/2016/5/51/T--LambertGA--techlogo.jpg">--> |
− | <img src="https://static.igem.org/mediawiki/2016/5/51/T--LambertGA--techlogo.jpg" style="width: | + | <img src="https://static.igem.org/mediawiki/2016/5/51/T--LambertGA--techlogo.jpg" style="width:450px"> |
</table> | </table> | ||
</div> | </div> | ||
<table> | <table> | ||
− | Our iGEM team | + | Our iGEM team was inspired for our project by the work in the Styczynski Lab at the Georgia Institute of Technology. Professor Styczynski and his graduate students, Monica McNerney and Daniel Watstein are currently working on engineering a zinc biosensor. (Watstein, McNerney and Styczynski 2015) Their use of the violacein and carotenoid pathway as a biosensor for zinc micronutrient deficiencies led us to investigate other visual detection sensors. Chromoproteins from the Uppsala 2013 collection seemed to be a natural place to start. The Endy Lab and Edinburgh's 2014 projects into "degrons" or degradation tags were also inspirations for our project. |
<!--<br><br> | <!--<br><br> | ||
.--> | .--> | ||
<br><br> | <br><br> | ||
− | In addition, | + | In addition, Dr. Styczynski and Monica McNerney have been mentors and advisors to us. They have met with us multiple times to revise our project and troubleshoot issues both in person and by Skype calls. Dr. Styczynski has also generously provided materials that a high school lab does not have access to, and has periodically allowed us use of his lab for training and use of specialized equipment. We could not have completed our project without this collaboration! |
</p> | </p> | ||
</table> | </table> | ||
Line 400: | Line 402: | ||
</div> | </div> | ||
<table> | <table> | ||
− | In order to further understand the impact of our project, we discussed | + | In order to further understand the impact of our project, we discussed micronutrient deficiencies with Dr. Ralph Whitehead, a researcher from the CDC. During the interview we asked questions about micronutrient |
+ | deficiencies in multiple regions around the globe. The insightful answers gave us a better understanding of the micronutrient problems that affect different areas. Micronutrient deficiencies are often unspecified through different regions because micronutrient amounts available in the soil can vary between agricultural fields within the same village. He shared the specific process of blood analysis for micronutrient amounts. He also named other organizations that are working on the development of a household indicator for blood analysis. The process from blood sampling to results and actions to resolve the deficiencies can take weeks and has enormous resource costs. The blood samples must stay refrigerated and travel long distances to clinics or labs. The results of the tests then needs to be delivered back to the patient and caretakers. Dr. Whitehead also touched on the CDC’s specific process for blood analysis in targeted areas and was interested in micronutrient biosensors as a promising solution to an ever growing problem. | ||
</table> | </table> | ||
<br><br><br> | <br><br><br> | ||
Line 412: | Line 415: | ||
</div> | </div> | ||
<table> | <table> | ||
− | In the spring, a representative from New England Biolabs, Chris Cook, came to our school to discuss restriction enzymes and other products that we use in our lab. The presentation was helpful not only on the scientific side, but | + | In the spring, a representative from New England Biolabs, Chris Cook, came to our school to discuss restriction enzymes and other products that we use in our lab. The presentation was helpful not only on the scientific side, but also because he discussed career opportunities beyond a research lab. |
</table> | </table> | ||
<br><br><br> | <br><br><br> |
Latest revision as of 21:01, 19 October 2016
Collaborations
![](https://static.igem.org/mediawiki/2016/2/26/T--LambertGA--purpleline.jpg)