Difference between revisions of "Team:LMU-TUM Munich"

Line 1: Line 1:
 
{{LMU-TUM_Munich|navClass=home}}
 
{{LMU-TUM_Munich|navClass=home}}
=LMU and TU Munich 2016=
+
=LMU & TU Munich 2016=
  
 
<ul class="slider">
 
<ul class="slider">

Revision as of 01:22, 17 October 2016

LMU & TU Munich 2016

  • Team Photo
  • Another Team Photo

Abstract: biotINK - rethINK tissue printing

Living in an aging society and facing the increasing organ shortage, we have developed a game-changing approach to bioprint tissues for biomedical application. Our interdisciplinary work entails creating a novel bioink that exploits the rapid and specific interaction of biotin and its tetrameric binding protein streptavidin. By employing this affinity, we have engineered cells presenting biotin moieties or biotin binding proteins on their surfaces and recombinant biotinylated proteins as spacer molecules, which both co-polymerize upon contact with streptavidin. Furthermore, we have explored different cellular circuits, which allow us to control pancreatic cell lines, induce tissue vascularization, or install biosafety mechanisms for printed tissues. To deliver these cells, we employ a hijacked 3D printer that enables us to manufacture three-dimensional multi-cellular structures in a user-definable manner. Altogether, we are confident that our system provides the necessary means to advance the SynBio community to the next level – the tissue level.


Sponsors

up button Back to top

LMU & TUM Munich

Technische Universität MünchenLudwig-Maximilians-Universität München

United team from Munich's universities

Contact us:

Address

iGEM Team TU-Munich
Emil-Erlenmeyer-Forum 5
85354 Freising, Germany