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Revision as of 01:25, 17 October 2016
Wichtiger Kommentar: Polymerization wird Proof-of-Principle page.
Introduction to polymerization
Design: Why we chose the Avidin & Biotin affinity pair
- Vergleich mit anderen Polymerisationsmöglichkeiten die wir diskutiert hatten
- Tabelle mit Literaturwerten zu Assoziationsraten
Affinity pair | Kind of interaction | Dissociation constant | Association rate | Comment |
Avidin - Biotin | non covalent | 10-15M [1] | 55 440 | |
SpyCatcher - SpyTag | covalent | not applicable | ||
StrepTactin - Strep-tag II |
Multivalency and avidity as major principles for polymerization
- Strukturmodeling
Different polymers possible with biotINK polymerization
- Mesh-Bilder von Luisa
Results: Polymerizationexperiments
In the Micromanipulator
File:Muc16 Mikromanipulator Poly.mov
References
- ↑ Green, N. M. (1963). Avidin. 1. The use of [14C] biotin for kinetic studies and for assay. Biochemical Journal, 89(3), 585.