VolkerMorath (Talk | contribs) (→Sponsors) |
VolkerMorath (Talk | contribs) (→Sponsors) |
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<li class="sponsor">[[Image:Muc16_Sponsor_Qiagen.png|link=http://www.qiagen.com/|alt=Quiagen]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_Qiagen.png|link=http://www.qiagen.com/|alt=Quiagen]]</li> | ||
<li class="sponsor">[[Image:Muc16_Sponsor_BioRad.JPG|link=http://www.bio-rad.com/|alt="Bio Rad]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_BioRad.JPG|link=http://www.bio-rad.com/|alt="Bio Rad]]</li> | ||
+ | <li class="sponsor">[[Image:Muc16_Sponsor_CarlRoth.png|link=http://www.carlroth.com|alt=Carl Roth]]</li> | ||
<li class="sponsor">[[Image:Muc16_Sponsor_Faust.jpeg|link=http://www.faustlabscience.de/|alt=Faust]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_Faust.jpeg|link=http://www.faustlabscience.de/|alt=Faust]]</li> | ||
<li class="sponsor">[[Image:Muc16_Sponsor_Eppendorf.png|link=http://www.eppendorf.com/|alt=Eppendorf]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_Eppendorf.png|link=http://www.eppendorf.com/|alt=Eppendorf]]</li> | ||
<li class="sponsor">[[Image:Muc16_Sponsor_ibidi.gif|link=http://www.ibidi.com/|alt=Ibidi]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_ibidi.gif|link=http://www.ibidi.com/|alt=Ibidi]]</li> | ||
<li class="sponsor">[[Image:Muc16_Sponsor_Satorius.jpeg|link=http://www.sartorius.de|alt=Sartorius]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_Satorius.jpeg|link=http://www.sartorius.de|alt=Sartorius]]</li> | ||
− | |||
<li class="sponsor">[[Image:Muc16_Sponsor_Abcam.png|link=http://www.abcam.com/|alt=Abcam]]</li> | <li class="sponsor">[[Image:Muc16_Sponsor_Abcam.png|link=http://www.abcam.com/|alt=Abcam]]</li> | ||
</ul> | </ul> |
Revision as of 17:47, 30 November 2016
Abstract: biotINK - rethINK tissue printing
We are living in an aging society that is facing a decreasing supply of donor organs. To confront this pressing issue, we developed a game-changing approach to bioprint tissues for biomedical applications. Our interdisciplinary work aims to create a unique ink, named biotINK, to revolutionize bioprinting. The printing process uses a hijacked 3D printer and two components of biotINK to induce an instantaneous polymerization reaction, creating three-dimensional multi-cellular structures in a user-definable manner. The principle of this two-component glue relies on the rapid and specific interaction of biotin and its tetrameric binding protein avidin. To make use of this high biotin-avidin affinity for cell-cell cross-linking, we engineered cells presenting biotin moieties or biotin-binding proteins on their surfaces as well as recombinant matrix proteins, which co-polymerize upon printing. Furthermore, we explored different genetic circuits which allow us to functionalize the bio-synthetic tissue and install biosafety mechanisms.
Altogether, we are confident that our system provides the necessary means to advance the SynBio community to the next level – the tissue level.