Team:MIT

• BACKGROUND
• EXPERIMENTS
  Synthetic Promoters microRNA Recombinase Proof of Concept Collaborations
• FUTURE WORK
  Circuit Design Clinical Applications
• HUMAN PRACTICES
  Parts Toolbox Accessible Protocols Integrated Human Practices Public Outreach Interlab Study
• NOTEBOOK
  Lab Notebook Parts Mammalian Parts Collection Attributions Safety
• AWARDS
  HP Silver HP Gold Integrated HP Basic Part
• TEAM

Read more about endometriosis

This diagnostic process can be expedited by using the following synthetic biological tools to sense molecular markers in endometrial biopsy samples.

Respond to malfunctioning of hormone sensing in endometriosis




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  Identify cells in disease state through dysregulated miRNA activity
  
  
  
  
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  Give the circuit a form of memory through a biological latch system
  
  
  
  
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  Explore how our sensors interact logically by transfecting 4 to 5-unit genetic circuits into model cell cultures
  
  
  
  
  
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We've successfully created new, hormone-inducible mammalian promoters,
characterized miRNA sensors in a model cell line under varying estrogen conditions,
and tested the functionality of a serine integrase (TP901) in a mammalian line.

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  Read more about the future of our work through circuit design, clinical application, and iGEM collaborations
  
  

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